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World Health Organization warns Gonorrhea Could Join HIV as 'Uncurable'
U.S.News & World Report ^ | June 6, 2012 | Jason Koebler

Posted on 06/07/2012 9:30:08 AM PDT by neverdem

Both the WHO and the CDC say it's time to "sound the alarm" on the increase in drug-resistant gonorrhea

First, it was the Centers for Disease Control—now, the World Health Organization is warning that Gonorrhea could join herpes and HIV/AIDS as "uncurable" sexually-transmitted diseases.

"We're sitting on the edge of a worldwide crisis," says Manjula Lusti-Narasimhan, of WHO's department of reproductive health and research. "There's a general complacency around sexually transmitted infections in general, and this doesn't have the same political or social pressure as HIV. That's because gonorrhea has been so easily curable so far, but in the future, that won't be the case."

Gonorrhea is estimated to infect more than 100 million people worldwide each year and can cause infertility, ectopic pregnancy, painful urination, and severe eye infections to babies born to women infected with the disease.

[Antibiotic-resistant bacteria found in 37 states]

So far, drug-resistant strains of gonorrhea have shown up in the United States, Norway, Sweden, Austria, the United Kingdom and other countries.

All of those cases were cured with cephalosporins, an antibiotic that doctors say is the "last line of defense" against gonorrhea before moving on to injectable antibiotics. Last year, there was one published case of a strain of gonorrhea that showed resistance to injectable antibiotics as well. Lusti-Narasimhan says those cases will soon be the norm.

In February, the CDC estimated that about 1.7 percent of gonorrhea samples (taken from men with gonorrhea at STD clinics in 30 U.S. cities) was resistant to cephalosporins, a 17-fold increase since 2006.

"If [gonorrhea] didn't cause so much trouble, it'd be a really fascinating organism to study—it's a superbug, a really smart organism," she says. "It not only develops resistance rapidly, but it retains memory of past resistance, so you can't say 'Let's try out penicillin' because [the bacteria] has a memory for it."

[Hospital Rooms Crawling With Drug-Resistant Germs.]

The bacteria's penchant for building up resistance has put drug companies in a tough place—developing a new antibiotic is expensive and unlikely to be profitable, and within a few years, gonorrhea would likely develop a resistance to any new drugs used on it, she says.

"Drug manufacturers are in a bizarre scenario—why would they spend a ton of money developing a new drug for what was, until now, one of the most easily treatable STI's?" she says. "They know if they do develop a new drug, it's going to rapidly develop resistance."

So far, every case of gonorrhea in the United States has been treatable through some combination of antibiotics, according to the CDC. In an E-mail, CDC spokesperson Nikki Mayes says it's time for the international health community to "sound the alarm" that untreatable gonorrhea is on the way.

"The bottom line is that treatment of gonorrhea with cephalosporins remains effective [in the United States], and no cases of treatment failures have been seen in the U.S," she wrote. "But we do want people to be aware that if new treatments aren't developed, we may see untreatable gonorrhea in the future."

Jason Koebler is a science and technology reporter for U.S. News & World Report. You can follow him on Twitter or reach him at jkoebler@usnews.com.



TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: cephalosporins; gonorrhea; microbiology; moralabsolutes; rkselection; std

1 posted on 06/07/2012 9:30:17 AM PDT by neverdem
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To: neverdem
This makes me wonder. Is there any fool proof way to avoid catching a sexually transmitted disease?

Hmmmm...

2 posted on 06/07/2012 9:38:49 AM PDT by Rides_A_Red_Horse
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To: neverdem

Well, I’ll guess we’ll just have to tax having pre-marital sex and/or having multiple partners like we do tobacco.

That could also be part of those “wellness plans” that insurance companies have and will be force-majeur as part of obamacare.


3 posted on 06/07/2012 9:48:02 AM PDT by fruser1
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To: Rides_A_Red_Horse

“Is there any fool proof way to avoid catching a sexually transmitted disease?”

No. The propaganda tells us that it has nothing to do with actions or behavior.


4 posted on 06/07/2012 9:49:47 AM PDT by mikey_hates_everything
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To: mikey_hates_everything

“The propaganda tells us that it has nothing to do with actions or behavior.”

Exactly, and as an RN, I know they were seeing this antibiotic resistance in the 80’s not long after they discovered AIDS. Political correctness should have nothing to do with medicine.


5 posted on 06/07/2012 10:03:16 AM PDT by pops88 (Standing with Breitbart for truth.)
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To: Rides_A_Red_Horse

“And the Gods of the Copybook Headings said ‘The wages of sin is death’”.


6 posted on 06/07/2012 10:19:27 AM PDT by M1903A1 ("We shed all that is good and virtuous for that which is shoddy and sleazy... and call it progress")
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To: mikey_hates_everything

Umm, doorknobs or toilet flush handles, maybe?

There is a form of treatment, not widely used in the West, that attacks the pathogens directly, rather than through the antibiotic therapy regimen. Disease organisms, pathogens, are themselves subject to deadly diseases that attack them at the cellular level, invading the central living portion of the cell. This bacteriophage therapy has been developed in Eastern Europe and the Russian Federation, and is highly specific for each microorganism species. Things like MRSA, resistant to the usual antibiotics, are treated successfully by an infusion of this specific culture.

So far as I understand the biological action, these bacteriophages are almost considered a virus, and in the absence of the host cell, they revert to a dormant state.


7 posted on 06/07/2012 10:33:13 AM PDT by alloysteel (Fear and intimidation work. At least on the short term.)
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To: neverdem

When they first started reporting about AIDS in the media, they told us in 20 years we will all have a close friend or relative dead of AIDS. Well, here it is 30 years later and this disease still infects a MINISCULE number of americans.

15 years ago(maybe more) the media started telling us about a new “superbug” version of tuberculosis that came out of soviet prisons that was drug resistant and highly virulent. They said there was no cure for it and it would soon become a pandemic. Well, here it is 15 years later and virtually no one in america has this disease.

SARS, west nile virus, hantavirus, swine flu, bird flu, lyme disease, Ebola...all of these were supposed to be the next pandemic. Never happened.

Polio and leprosy were supposedly making a comeback in the third world and would spread to the developed world due to vaccines no longer being produced. Never happened.


8 posted on 06/07/2012 10:40:54 AM PDT by mamelukesabre
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To: alloysteel

“Umm, doorknobs or toilet flush handles, maybe?”

Maybe, but then it’s not an STD—spread by actions or behavior.


9 posted on 06/07/2012 10:48:39 AM PDT by mikey_hates_everything
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To: neverdem

Action and consequence.


10 posted on 06/07/2012 11:15:39 AM PDT by ThinkingBuddha
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To: neverdem

Incurable not uncurable


11 posted on 06/07/2012 11:19:20 AM PDT by Mashood
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To: alloysteel
So far as I understand the biological action, these bacteriophages are almost considered a virus,...

A bacteriophage is a virus that infects bacteria.

12 posted on 06/07/2012 11:53:16 AM PDT by neverdem (Xin loi minh oi)
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To: mamelukesabre
15 years ago(maybe more) the media started telling us about a new “superbug” version of tuberculosis that came out of soviet prisons that was drug resistant and highly virulent. They said there was no cure for it and it would soon become a pandemic. Well, here it is 15 years later and virtually no one in america has this disease.

Thanks to the grace of God and our surveillance systems. IMHO, multidrug-resistant, mdrtb, and extensively drug-resistant, xdrtb forms of tuberculosis are more prevalent than you appreciate.

13 posted on 06/07/2012 1:15:13 PM PDT by neverdem (Xin loi minh oi)
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To: neverdem

well, I did not know it was happening in east asia...but as you can see by this map, it is essentially ZERO in the USA. Looks to be the worst in sub sahara africa.

http://en.wikipedia.org/wiki/File:Tuberculosis-prevalence-WHO-2009.svg


14 posted on 06/07/2012 1:52:55 PM PDT by mamelukesabre
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To: neverdem
Wonder why they left out drug resistant syphilis? That one has had them stumped since the late seventies.
15 posted on 06/07/2012 2:37:29 PM PDT by MrEdd (Heck? Geewhiz Cripes, thats the place where people who don't believe in Gosh think they aint going.)
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To: mamelukesabre; alloysteel

I think, looking at the chart that it must have something to do with being able to speak English.

http://en.wikipedia.org/wiki/File:Tuberculosis-prevalence-WHO-2009.svg


16 posted on 06/09/2012 8:15:24 AM PDT by B4Ranch (There's Two Choices... Stand Up and Be Counted ... Or Line Up and Be Numbered .)
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To: M1903A1

Excellent. It isn’t funny that two generations of school children will be forced to relearn millenia of human wisdom.

They’ve jailed Natural Law, but the walls and bars won’t hold that monster.


17 posted on 06/09/2012 2:08:43 PM PDT by 1010RD (First, Do No Harm)
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To: neverdem

Sometimes I get the feeling the world is purposely designed to be K-selected, in a way we can’t imagine, since we can’t see the alternatives.

Let things get too “r” for too long, and a myriad of things happen, which all seem perfectly designed to unavoidably turn the balance back towards K-selection.


18 posted on 06/09/2012 7:32:24 PM PDT by AnonymousConservative (Why did Liberals evolve within our species? www.anonymousconservative.com)
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To: alloysteel

Phages are cool. I believe Neisseria (gonorrhea) is actually one genus which they still don’t have a phage for though, at least as of a few years ago. But I might be mistaken.

I wonder if infected people will begin trying to infect others through door handles in public toilets, putting the seat down and contaminating it, etc.

I remember a few people infecting innocents with AIDs back in the 80’s, with the idea that if everybody had it they would be more likely to get a cure. I think the type of people who are most likely to get these things, also have psychologies which can be exceedingly selfish, and evil.

Buy stock in Purell.


19 posted on 06/09/2012 7:42:53 PM PDT by AnonymousConservative (Why did Liberals evolve within our species? www.anonymousconservative.com)
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To: Rides_A_Red_Horse

Natural Law - making the case for heterosexual marriage, one disease at a time.


20 posted on 06/09/2012 8:42:19 PM PDT by 1010RD (First, Do No Harm)
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To: AnonymousConservative

You have an interesting theory, but according to biologists neither strategy is superior. If so, how do they account for human dominance of the planet?


21 posted on 06/09/2012 8:49:32 PM PDT by 1010RD (First, Do No Harm)
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To: 1010RD

They don’t. My opinion, based on the evidence, is this, and I hold it very strongly.

r-strategists were first characterized because scientists wanted to understand invasive species, and why they exploded in number in a new environment, while other species would multiply more slowly. It turns out invasive species followed the r-strategy, and as a result, they could multiply incredibly fast - but only in times of ease, and free resource availability. And they didn’t produce the kind of evolutionary complexity and fitness which would allow them to take over harsher, more fitness-requiring environments.

K-s produce fitness, due to their embrace of competition, but they multiply slower, so they don’t spread as well.

The advantage humans had was our pre-Liberal r’s took off when our home territory overpopulated, and turned K. They spread into every area where resources were freely available, and the environment didn’t require high fitness. They were a human version of an invasive species, and their r-strategy fueled their spread.

As the r’s exhausted each new areas’ resources, things got competitive and they fled, and behind them emerged the K’s who then competed with each other for resources, and established fitter populations which multiplied slower, more in harmony with the environment. As the whole planet fell to us, fitter, more able K’s also spread into, and colonized harsher environments, which required higher levels of fitness to survive.

Humans gained superiority because we combined the invasive species qualities of r at the edge of our spread, with the fitness of K as we acquired a firm foot hold in each new territory. Once established worldwide, our K-natures embraced competition, and evolved us to this state, with the fittest periodically spreading out and taking land over from the less adapted, worldwide.

The main advantage of my work to politics is that Liberals can’t dispute it. Liberalism embraces every value of “r” and Conservatism embraces every value of “K.” And telling everyone that freaks Liberals out, since they can’t refute it.


22 posted on 06/11/2012 9:52:41 AM PDT by AnonymousConservative (Why did Liberals evolve within our species? www.anonymousconservative.com)
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To: AnonymousConservative

True liberals do not reproduce rapidly. The slugs who leach off of society and vote for liberals to keep the free stuff coming DO reproduce rapidly. But those are not true liberals. They are just barely conscious marginally useful bags of meat who do not really have any agenda that extends beyond next week’s paycheck.


23 posted on 06/12/2012 10:48:56 AM PDT by mamelukesabre
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To: 1010RD; Natural Law
They’ve jailed Natural Law, but the walls and bars won’t hold that monster.

Dude ... Seriesly?

24 posted on 06/12/2012 10:57:14 AM PDT by ArrogantBustard (Western Civilization is Aborting, Buggering, and Contracepting itself out of existence.)
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To: Rides_A_Red_Horse

>This makes me wonder. Is there any fool proof way to avoid catching a sexually transmitted disease?<

Good thing rape is illegal...


25 posted on 06/12/2012 10:58:42 AM PDT by Darnright ("I don't trust liberals, I trust conservatives." - Lucius Annaeus Seneca)
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To: ArrogantBustard; 1010RD
"They’ve jailed Natural Law, but the walls and bars won’t hold that monster."

"But on arriving at the jail, the officers did not find them there. So they went back and reported, “We found the jail securely locked, with the guards standing at the doors; but when we opened them, we found no one inside.”" - Acts 5:22-23

26 posted on 06/12/2012 11:56:38 AM PDT by Natural Law (Jesus did not leave us a Bible, He left us a Church.)
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To: mamelukesabre

“True liberals do not reproduce rapidly. “

Yes, but why do true Liberals reproduce more slowly? Less mating? Less promiscuity? Some K-aspect to their nature? Nope, it’s birth control and abortion.

GSS and gallup data show Libs are more likely to be more promiscuous and support single parenting and out of wedlock births more. In a state of nature that would increase birth rates. It still will, among the more impulsive, less intelligent, less responsible, and less conscientious, who don’t stick to a birth control regime.

But the intelligent and conscientious Liberal’s birth rates are cut because one of the r-strategy’s traits is to seek to minimize parental investment. In nature, where sex always leads to preganncy, this would raise reproductive rates, because you spend less on each child, and can therfore produce more total children.

Modern Liberals, though can use birth control and abortion to eliminate parental investment. And they do. Abortion has killed 50 million, who were probably mostly Lib offspring.

Add in a hundred million or two hundred million, or more whose conception was prevented through birth control, and you would have higher Lib birth rates. Imagine how these urges to promiscuity and low-investment rearing played in primitive times, before we even were conscious of the fact that sex made babies, and you would have even more births.

Of course, my point is not that Libs are “r” (though you can argue that). If you want to extrapolate, you can een argue that Libs probably descended from r’s, and you would probably be right, since they have all the urges.

But my core observation, which is wholly inarguable, is that Liberalism as an ideology embodies every “r” trait, even if the minimizing parental investment trait cuts birthrates among some Liberals, when combined with modern technology. And this is why issues of family intertwine as they do with issues of economics, issues of foreign policy, and issues of personal freedom.


27 posted on 06/12/2012 1:25:36 PM PDT by AnonymousConservative (Why did Liberals evolve within our species? www.anonymousconservative.com)
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