This is the natural, normal-state condition for humans, along with need for rest and relaxation and the twin desire to experience pleasure and avoid pain.
Otoh, excessive self-medication, whether with substance or activity, is more likely a symptom of underlying problems in the environment, rather than being the actual problem itself.
Those responsible for creating these environments that are harmful to the human spirit also like easy scapegoats to blame for their resulting problems.
So, the symptoms become the problems to be treated, while the actual cause goes unaddressed and the problems get worse, creating evermore symptoms requiring more and more solutions.
We're from GovCo and we're here to help.
Rest assured that we're not satisfied till you're not satisfied.
That, you can count on!
The classic Christian explanation is that humanity chose, as a group, to figure out for itself what was right, rather than letting the good Lord show them. And this was a failure.
However the good Lord did not cease to desire to bless humanity. The catch is that the Lord can only bless what is conducive to carrying out His good will. There is a certain way the Lord created humanity to work, and other ways lead to tragedy, not blessing.
Is it possible in principle that a person could use some things that are currently banned by man (but not by God) in a moderate, controlled way that would be blessed? Yes. Are actual addicts disposed to do that? No.
What needs to have an onus on it is misbehavior, not things that are misused.