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Smallpox vaccinations urged (MSNBC) - Offer to general population represents a shift in policy
http://www.msnbc.com/news/817382.asp ^ | 10-5-02 | MSNBC

Posted on 10/05/2002 6:34:56 PM PDT by bonesmccoy

WASHINGTON, Oct. 5 — The Bush administration’s top bioterrorism advisers said yesterday they support a voluntary smallpox vaccination program that would begin with 500,000 health care workers, expand to 10 million emergency responders and extend to the rest of the population as early as 2004.

IT WAS THE first time high-ranking administration officials acknowledged they are considering offering the risky vaccine to the public prior to an attack and it represented a profound shift in thinking from the June recommendations of a government advisory panel to inoculate about 20,000 medical personnel.

“We live in a society that values individual choice,” said Julie L. Gerberding, director of the Centers for Disease Control and Prevention. “If we have vaccine and we have data to accurately assess the safety, one school of thought is that informed people may want to have the choice of getting vaccine or not.”

In a 90-minute briefing at the Department of Health and Human Services, the group of officials responsible for implementing a bioterror response plan laid out the options before President Bush, stressing that he has yet to make a decision on who could be vaccinated and when. If a smallpox case were detected, officials would assume the nation was under attack and would quickly move to nationwide vaccination.

Developing a “pre-attack” vaccination policy, however, has proven to be “extremely difficult” because of the challenge in balancing the possible risks of the vaccine against the risks of an attack, said Jerome M. Hauer, assistant secretary for emergency health preparedness.

THREAT OVERCOMES CONCERNS

Although they have no way of knowing the likelihood of a smallpox attack, health experts fear such an attack because the virus is so contagious and so deadly. About one-third of people who get the disease die, yet the vaccine itself can cause serious, sometimes fatal, complications.

Concerns that Iraq or another hostile nation may have acquired the virus have added urgency to the vaccination debate. “We need to be mindful that the context of this decision has changed a bit” since the far more conservative June recommendations, Gerberding said.

Vice President Cheney has speculated that the threat from Iraqi President Saddam Hussein may necessitate mass vaccination. Privately, sources said Cheney has vigorously advocated a broad vaccination policy. White House spokesman Scott McClellan said last night the policy “is under review” but he could not elaborate on a timetable or factors involved in the decision.

Since last fall’s anthrax attacks, federal health officials have moved swiftly to build up the nation’s smallpox vaccine stockpile. If an attack occurred today, they said they could safely dilute the existing supply to inoculate every American. By the end of next year, they expect to have 209 million doses of new vaccine on hand. None of the vaccine has been licensed by the Food and Drug Administration, but officials expect the first batches will be approved by November.

MILITARY FIRST IN LINE

At the request of the Department of Defense, Hauer said HHS will provide the first 1 million doses of licensed smallpox vaccine to the military within the month. Pentagon spokesman James Turner refused to comment.

For civilians, the HHS team favors a policy of “ever-expanding access to vaccine” that could be phased in as more vaccine is licensed and scientists have time to monitor early reactions to it. Using licensed vaccine would be much easier logistically than administering it as an experimental treatment that involves tricky liability issues.

The approach envisions vaccinating the people considered to be at greatest risk if an outbreak occurs. That would include public health investigators, emergency room workers and even janitors and security guards at local hospitals.

The goal in the early stages, Gerberding said, “is to maximize our ability to respond to an attack should one occur.”

In the second phase, as many as 7.5 million medical workers would be offered vaccine, along with the nation’s 3 million firefighters, police officers and rescue workers, Hauer said. Inoculating that many emergency personnel “would make it even easier to respond” to an attack, Gerberding explained. It is possible Bush would combine the first two phases and opt to inoculate the majority of first responders immediately.

At some later date, perhaps in early 2004, vaccine could be offered to every American. “Right now, our thinking is in favor of making vaccine available to the general public,” Gerberding said.

Federal health officials rejected the advice of its advisory panel to designate certain smallpox hospitals because Hauer said it was unrealistic to think patients would follow those guidelines.

America stopped routine vaccination in 1972, which means about 45 percent of the population has never been inoculated. It is unclear how much immunity remains from vaccines given 30 or 40 years ago.

Between 30 million and 50 million Americans should not be given the vaccine because they have weak immune systems, said Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases. That includes people who have received chemotherapy, have eczema or are infected with the AIDS virus. For every 1 million vaccinated, 15 people are likely to suffer life-threatening complications and one or two would die.

Because there is limited scientific data, it is difficult to predict the risks of a person spreading the virus in the vaccine to others. Administration aides are still grappling with the liability issues of reviving a vaccination program.

State health officials have until Dec. 1 to file plans for mass vaccination within five to 10 days of an attack, Hauer said. In the event of an attack, he observed, “Five days might be a luxury.”

(Excerpt) Read more at msnbc.com ...


TOPICS: Activism/Chapters; Announcements; Breaking News; Business/Economy; Foreign Affairs; Front Page News; Government; Miscellaneous; News/Current Events
KEYWORDS: bioterrorism; wmd
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To: Fred Mertz
for anthrax is what I was referring to.
41 posted on 10/05/2002 8:37:08 PM PDT by Fred Mertz
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To: Robert_Paulson2
I think the new vaccine is at least as good as the old vaccine. I guess the most generous interpretation of this is to say that, the estimated 1,000 deaths that would follow from immunizing the entire population might have been justified when smallpox was a concrete (natural) threat, but, in the face of a hypothetical threat, it's a tough call, and waiting till after an attack might be a better strategy.

Another interpretation, which I have suggested, is that the remote, hypothetical smallpox threat makes a convenient cover story or stalking horse for rolling out civil defense measures against the very concrete threat presented in the anthrax letters, and presented by Saddam Hussein's known heavy investment in anthrax as a poor man's alternative to nukes. I don't want to oversell this, because I think the first interpretation is arguable, but I couldn't help but be amused by the CDC director's apparent freudian slip during the interview, substituting "anthrax" for "smallpox." It does fit with my idea that their is a disconnect between what these people are worried about behind the scenes, and the comfortably hypothetical proxy threats they talk about in public (smallpox, suitcase nukes, dirty nukes, etc.)

42 posted on 10/05/2002 8:40:18 PM PDT by The Great Satan
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To: Fred Mertz
Other antibiotics work on it too, I was told.
But I think "cipro" is the current "cadillac" of antibiotics...
43 posted on 10/05/2002 8:42:41 PM PDT by Robert_Paulson2
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To: Fred Mertz
I thought Cipro was the day after treatment of convenience.

Well, the government also put in an order for 100 million doses of Cipro after the anthrax attacks of last year, so that's in the stockpile already (U.S. buying 100 million doses of anthrax antibiotic). The problem is that it is generally very easy to add antibiotic resistance to bacteria -- it doesn't require sophisticated genetic engineering, just routine lab techniques -- so it's all too possible that they only used antibiotic-susceptible anthrax for the warning letters for operational reasons, i.e. to protect the senders from accidental death and subsequent exposure. I bought 60-day supplies of Doxy and Cipro after the anthrax scare, but I honestly don't have that much faith they would be much help in a real attack. The anthrax vaccine has a completely differnt mode of action and probably would save a lot of lives -- if we can put in place the infrastructure to deliver it to millions of people in a very short space of time and if we can figure out how to avoid complet, Panic in the Streets-style social disintegration when the news hits of the first few hundred people checking into St. Vincent's with respiratory problems. Those are big ifs, IMO.

44 posted on 10/05/2002 8:51:04 PM PDT by The Great Satan
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To: The Great Satan
With half us already "vetted" with the old vaccine which I am told is remarkably strong even after forty or fifty years, and the other half selectively immunized in pockets where attacks have occured... there would probably not be nearly as many as 1000 dead, I am guessing. More like 250 sick, with a few immuno deficiency types and elderly "already on death's door" being at risk of death... probably LESS than the west nile virus deaths.

Their goal is not just our death... it's to cripple our commerce and infrastructure... They are terrified of our ability to work and make a living... and export FREEDOM to the world. The world they think is THEIRS... to rule over.
45 posted on 10/05/2002 8:54:58 PM PDT by Robert_Paulson2
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To: The Great Satan
any idea how long after weaponized anthrax were used, we would have to get a useful dose of the vaccine... 48 hours, or less?
46 posted on 10/05/2002 8:56:57 PM PDT by Robert_Paulson2
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To: Robert_Paulson2
I really think that al-Qaeda is pretty ineffectual. Yeah, I think we should find these muslim whackos and lock 'em up and throw away the key whenever we do -- I'm all for that. But I think the best way to conceptualize this is that al-Qaeda is a gang of fanatical morons who are largely incapable of doing anything themselves, but who provide a convenient repository of muscle for much more sophisticated thugs, notably Saddam Hussein. There is an enormous gap in sophistication between the 9-11 operation and most of the other al-Qaeda activities we have seen, such as the shoe bomber or the LAX shooter. It's the same if you look back to the original attempt on the WTC. A bunch of dim-witted losers were planning pipe bomb attacks on Jews in Brooklyn, and then all of a sudden this very mysterious, sophisticated, very un-Islamic figure, "Ramzi Yousef" (to use one of his many names) appears out of nowhere (actually, he was carrying an Iraqi passport) and redirects them into an attempt to knock down the WTC and kill 200,000 people. Something else is going on here, something quite different from what most people imagine.

This is not to say that al-Qaeda is not dangerous. In the first place, the establishment of an "Assassination Bureau" of would-be suicidal human missiles, ready to be contracted out to generic anti-Jewish and anti-American missions, is a revolutionary military development. Mate these suicidists to low-tech, biological WMD, and you have something every bit as revolutionary as the nuclear-tipped ICBM. In the second place, the impressive discipline and economy of means demonstrated in the 9/11 attacks may educate and inspire them to higher things. (Note, however, that the Islamists will never learn how to build jet airliners and skyscrapers -- there are limits to the "monkey see, monkey do" principle.) But, I think we need to get real: these people did not go from being a ragtag bunch of miscreants to an efficient, hyper-intelligent mobile fighting force overnight. They are still dorks. But smart people can build great empires on the backs of dorks, after all. Our real concern should be the "brain bug" in Baghdad, not a bunch of wankers living in a bedsit in Joisey.

47 posted on 10/05/2002 9:12:33 PM PDT by The Great Satan
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To: Robert_Paulson2
Well, there is only one way an attack can occur, and that is if someone in the United States or Russia makes the virus available to terrorists

Does this mean that someone in the United States or Russian government couldn't use the virus for a direct attack? Without going through terrorists as a third party? It would be so easy for either government to launch an attack and avoid repurcussions by just blaming it on faceless terrorists.

48 posted on 10/05/2002 9:19:17 PM PDT by templar
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To: Miss Marple
At some point you have to have a little trust, and this administration is trustwowrthy.

How so?

49 posted on 10/05/2002 9:21:21 PM PDT by templar
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To: Robert_Paulson2
any idea how long after weaponized anthrax were used, we would have to get a useful dose of the vaccine... 48 hours, or less?

I don't know the answer to that question. 1-3 days would be my stab-in-the-dark guess. Part of the problem is that the efficacy of any post-attack treatment, whether it be a vaccine, an antitoxin, or an antibiotic, is going to drop off the longer after the attack it is given. That means that, after an attack, everyone is going to be very conscious that it's a race against time, and a race against the other fellow, with literally life-and-death stakes. I really don't see any way around that, unless the meds can be pre-distributed, but I've never seen any sign of willingness to do that. The authorities have always gone out of their way to discourage people from acquiring medications prospectively. Of course, that may change when a showdown with Saddam is in the offing. Perhaps there is some kind of intermediate solution. For example, if we have enough stocks on hand, they could be distributed to every corner drug store, so that everybody could have some reasonable assurance of getting treatment promptly. They'd have to self-treat, but again, as this comes closer to a climax, the necessary education steps could be taken to make that feasible, at least if the vaccine can be administered orally. That approach would also be fool-proof against any terrorist attempt to disrupt distribution (e.g. 2AM - drop anthrax on subway tracks, 10 AM - suicide attack on treatment center).

50 posted on 10/05/2002 9:27:09 PM PDT by The Great Satan
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To: concerned about politics
Russia lost some of it's very heavy nukes.

Has anyone ever proven this? I mean, has anyone ever confirmed that any nukes are actually physically missing and not just administratively lost. The same way we sometimes loose tanks or rockets?

51 posted on 10/05/2002 9:27:29 PM PDT by templar
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To: RottiBiz
The death rate from the vaccine is one to two people per million

I wonder how this was determined. Vaccinated at least a million people in a study?

52 posted on 10/05/2002 9:29:32 PM PDT by templar
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To: Robert_Paulson2
any prophylactic antibiotic that is effective?

No antibiotics, But flamethrowers would probably work. Call it the andromeda solution.

53 posted on 10/05/2002 9:32:29 PM PDT by templar
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To: Robert_Paulson2
... lead and brass items... potential martial law... would be a necessary consideration.

Under martial law, you'd probably be better off not getting found in possession of lead and brass items. Unless, maybe, you'r referring to mickey mouse statues.

54 posted on 10/05/2002 9:36:36 PM PDT by templar
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To: templar
It's based on previous experience with DryVax by Wyeth during the 1970's. Some are concerned that immunocompromised people (i.e. AIDS patients) could contract fatal complications if given DryVax. Because HIV was not around at the time the DryVax was originally used, there is uncertainty regarding the risk. However, these risks are similar to existing risks related to the other live virus vaccines we use (though admittedly, higher risk with DryVax). Still, since the enemy has small pox biological weapons (according to FAS.org and other sources), the vaccine must be distributed in order to comply with the federal gov'ts role to "provide for common defense and promote the general welfare".
55 posted on 10/05/2002 9:40:22 PM PDT by bonesmccoy
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To: Robert_Paulson2
Anytime I see an article that relates to a thread that has been posted, I don't really see a problem with introducing it... even if it is by dickh#$d morris, or james carville.

There are a lot more readers than posters. The articles are for them as well. It does sort of help to indicate that the article doesn't nescessarily reflect your opinion though. For the sake of the posters who might assume otherwise.

56 posted on 10/05/2002 9:42:43 PM PDT by templar
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To: Miss Marple
Miss Marple,
I've heard others bantering about a conjectured possibility of having a "mutated variety of smallpox". I highly doubt it. Testing of such a strain would require human subjects and the testing organization would need to be certain that their entire staff was previously immunized against the disease. The molecular engineering and testing of the product is not straightforward and it would be difficult to contain the virus from the general population. So, no, I doubt this is a likely scenario at this juncture. In the future as certain biotechnologies become more widespread (and we may want to assess our import/export restrictions on some molecular biology reagents and equipment), this threat may become more likely. However, I really doubt the ability to use this technique without having significant collateral damage to your own side (who are presumably unimmunized also).
57 posted on 10/05/2002 9:45:39 PM PDT by bonesmccoy
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To: Dark Wing
ping
58 posted on 10/05/2002 9:46:14 PM PDT by Thud
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To: Robert_Paulson2
is this a different vaccine for a different "strain" of militarized small pox, you think?

My question here would be ... how would they know exactly what the strain was unless they had some of it? Something, I'm not sure just exactly what, is bothering me about all this smallpox vaccination stuff.

59 posted on 10/05/2002 9:48:20 PM PDT by templar
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To: Robert_Paulson2
Right. We don't have to worry about nuclear weapons either, because the weapons-grade fissionables required do not occur in nature.
60 posted on 10/05/2002 9:49:36 PM PDT by Thud
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