This do good Bishop could end up killing a lot of druggies.
The half life of Naloxone is very short time wise. Druggies with a heavy over dose could respond positively and seem okay. Then a couple of hours later the Naloxone blood levels could be below therapeutic levels. Then, the patient could fall back into a serious OD problem, renarcotisation, again.
“the pharmacodynamic actions of naloxone last for a briefer period than all but the most short acting opioids;8,24,29,31 although the elimination half life of naloxone is similar to that of morphine (6090 minutes)9 it is redistributed away from the brain more rapidly.32 Consequently, the patients may become renarcotised and suffer harm if they self discharge from medical care early. Clinicians are clearly walking a tightrope between precipitating AWS and avoiding renarcotisation.”
?Source Please?
Thx