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Microbes: Fighting Mosquito-Transmitted Viruses With Bacteria That Infect Many Insects
NY Times ^ | January 5, 2010 | DONALD G. McNEIL Jr.

Posted on 01/06/2010 8:07:43 PM PST by neverdem

A type of bacteria that infects many insects may make mosquitoes more resistant to viruses that can be dangerous to humans, researchers have found.

The discovery could be helpful in the battles against two painful and sometimes fatal diseases, dengue and chikungunya.

Last year, researchers showed they could take Wolbachia bacteria from fruit flies and infect mosquitoes with it, cutting their already brief life spans by half. That discovery was important because most of the malaria transmitted by female mosquitoes is transmitted late in their lives. They must pick up the parasites by biting an infected human, and it takes days for them to mature and migrate to the salivary glands to infect the next human bitten.

Now, according a new report in the journal Cell, researchers from Australia and Brazil have shown that the Wolbachia infection makes the Aedes aegypti mosquito more resistant to dengue, which is also known as “breakbone fever,” and to chikungunya, known as “bending-up disease.”...

(Excerpt) Read more at nytimes.com ...


TOPICS: Culture/Society; News/Current Events; Technical
KEYWORDS: chikungunya; dengue; malaria; microbiology; wolbachia
A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium

Wolbachia are maternally inherited intracellular bacterial symbionts that are estimated to infect more than 60% of all insect species. While Wolbachia is commonly found in many mosquitoes it is absent from the species that are considered to be of major importance for the transmission of human pathogens. The successful introduction of a life-shortening strain of Wolbachia into the dengue vector Aedes aegypti that halves adult lifespan has recently been reported. Here we show that this same Wolbachia infection also directly inhibits the ability of a range of pathogens to infect this mosquito species. The effect is Wolbachia strain specific and relates to Wolbachia priming of the mosquito innate immune system and potentially competition for limiting cellular resources required for pathogen replication. We suggest that this Wolbachia-mediated pathogen interference may work synergistically with the life-shortening strategy proposed previously to provide a powerful approach for the control of insect transmitted diseases.

Fascinating!

1 posted on 01/06/2010 8:07:46 PM PST by neverdem
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To: neverdem
Wolbachia are maternally inherited intracellular bacterial symbionts

Fascinating in deed.

The mother passes on these bacteria and yet it halves the life of insect.

You would think that these bacteria would have either caused the host insects to become extinct or the host would have become resistant to the bacteria.

2 posted on 01/06/2010 8:44:37 PM PST by Pontiac
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To: Mother Abigail; EBH; vetvetdoug; Smokin' Joe; Global2010; Battle Axe; null and void; ...
micro ping

Viral phenomenon: Ancient microbe invaded human DNA

Team finds link between stomach-cancer bug and cancer-promoting factor

3 posted on 01/06/2010 8:47:10 PM PST by neverdem (Xin loi minh oi)
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To: neverdem

Diseases are not the only danger to humans from mosquito’s. About a year or so ago I became ill and my weight dropped from 195 down to 165 over the space of a few months. To make a long story short they eventually found a mass in my left lung and it looked like I might have lung cancer. I had surgery to remove the tumor and when they dissected it they found the mass was encapsulating two dead heartworm larvae. I researched the subject and found a couple of cases where the worms had grown to adulthood in humans.


4 posted on 01/06/2010 10:27:31 PM PST by Steel Bill
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To: 2ndreconmarine; Fitzcarraldo; Covenantor; Mother Abigail; EBH; Dog Gone; ...

Ping... (Thanks, neverdem!)


5 posted on 01/06/2010 10:43:51 PM PST by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing.)
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To: neverdem

Wouldn’t DDT work just as well, without the ma$$ive re$earch effort$?

Efficacy is known, and no birdie eggshells to thin...oh right, wasn’t that disproven?


6 posted on 01/06/2010 10:52:35 PM PST by petro45acp (Free Republic, the only thing working on this sorry Bagram interweb thingy! Thanks Free Republic!)
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To: petro45acp
Wouldn’t DDT work just as well, without the ma$$ive re$earch effort$?

Efficacy is known, and no birdie eggshells to thin...oh right, wasn’t that disproven?

DDT-resistant insects have additional genetic advantage that helps resistance spread

IMHO, more than one weapon is needed.

7 posted on 01/06/2010 11:44:10 PM PST by neverdem (Xin loi minh oi)
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To: neverdem

Might be a little out of the loop here. How can there be DDT resistant bugs if the substance has been banned since silent spring went wide....sometime in the 70’s?

Will hit the article.


8 posted on 01/07/2010 12:36:36 AM PST by petro45acp (Free Republic, the only thing working on this sorry Bagram interweb thingy! Thanks Free Republic!)
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To: Steel Bill
Bill, eughh, thanks for that [glad I had my breakfast first!].
Seriously, glad you got that sorted!
9 posted on 01/07/2010 2:36:20 AM PST by bethybabes69 (Between you, and whatever you call God, there is no authority, only an illusion of it.)
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To: neverdem

Fruit flies are like the Atlas Van Lines of bacteria. You name it, they got it...

Funny, for an insect so tiny.


10 posted on 01/07/2010 2:42:12 AM PST by djf (What has killed more people? 1) Guns in cars or 2) Cell phones in cars???? Do the math!!!!)
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To: Smokin' Joe

Thanks for the ping!


11 posted on 01/07/2010 9:42:06 AM PST by Alamo-Girl
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To: TenthAmendmentChampion

Ping.


12 posted on 01/08/2010 10:57:12 PM PST by nw_arizona_granny ( http://www.freerepublic.com/focus/chat/21813ht92/posts?page=1 [Survival,food,garden,crafts,and more)
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To: Smokin' Joe

Thanks for the ping.


13 posted on 01/08/2010 10:57:34 PM PST by nw_arizona_granny ( http://www.freerepublic.com/focus/chat/21813ht92/posts?page=1 [Survival,food,garden,crafts,and more)
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