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a Department of Safety Research on Biologics, National Institute of Infectious Diseases, Gakuen, Musashimurayama, Tokyo 208, Japan b Department of Bacteriology, Kinki University School of Medicine, Osakasayama, Osaka 589, Japan c Animal Production and Grassland Division, Japan International Research Center for Agricultural Sciences, Tsukuba, Ibaraki 305, Japan Received 5 December 1996; Revised 20 January 1997; accepted 21 January 1997. Available online 12 December 1997. Abstract Effects of calcium phosphate and aluminium hydroxide adjuvants with different physical properties were examined in guinea pigs for local histopathological reactions, electron-microscopical changes of macrophages and adjuvanticity on total IgG antibody response to subcutaneously administered...

In studying the preventive effects of vitamin D, researchers at the Moores Cancer Center at the University of California, San Diego, have proposed a new model of cancer development that hinges on a loss of cancer cells' ability to stick together. The model, dubbed DINOMIT, differs substantially from the current model of cancer development, which suggests genetic mutations as the earliest driving forces behind cancer. "The first event in cancer is loss of communication among cells due to, among other things, low vitamin D and calcium levels," said epidemiologist Cedric Garland, DrPH, professor of family and preventive medicine at the...

Vitamin D And Calcium Influence Cell Death In The Colon, Researchers Find ScienceDaily (Apr. 14, 2008) — Researchers at Emory University are learning how vitamins and minerals in the diet can stimulate or prevent the appearance of colon cancer. Emory investigators will present their findings on biological markers that could influence colon cancer risk in three abstracts at the American Association for Cancer Research meeting in San Diego. In a clinical study of 92 patients, supplementing diet with calcium and vitamin D appeared to increase the levels of a protein called Bax that controls programmed cell death in the colon....

Calcium tablets 'raise risk of heart attacks' By Nic Fleming, Medical Correspondent Last Updated: 2:28am GMT 16/01/2008 Calcium supplements taken by about a million women could increase their risk of suffering heart attacks and strokes, scientists said yesterday. Researchers found that women aged 55 and over who took the tablets to combat osteoporosis were almost 50 per cent more likely to have a heart attack than those given placebos. Their chances of having a stroke during the five years of the study were elevated by more than a third. Three million people in Britain suffer from osteoporosis, with one in...

Largest, longest study ever supports screening and prevention of osteoporosis.One bone mineral density test can accurately predict a woman's chance of spinal fractures 15 years down the line, new research shows. And, according to the largest and longest prospective study of osteoporosis ever, women who had a spinal fracture at the beginning of the study had four times the risk of sustaining another fracture later on. The bottom line: "Women need to talk to their doctors about the risk of osteoporosis," according to Jane Cauley, lead author of the study and professor of epidemiology at the University of Pittsburgh Graduate...

Calcium linked to dementia Last Updated: 1:27am BST 14/05/2007 Calcium and vitamin D in dairy products may help to cause brain damage and dementia in older people, new research suggests. Scientists believe too much calcium can narrow blood vessels in the brain, leading to neural damage. The effect may be compounded by vitamin D, which regulates calcium retention and activity. Researchers made the discovery after scanning the brains of 79 men and 153 women aged up to 86. All had at least a number of brain lesions - areas of tissue damage. But those consuming the most calcium and vitamin...

People taking powerful antacid drugs called proton pump inhibitors face an increased risk of hip fracture, University of Pennsylvania researchers report. Common proton pump inhibitors include Aciphex, Nexium, Prevacid, Prilosec and Protonix; they are often prescribed for stomach conditions such as gastroesophageal reflux disease (GERD). The report is published in the Dec. 27 issue of the Journal of the American Medical Association. "If you take acid-suppression medications on a chronic basis and you are 50 or older, your hip fracture risk is even higher than usual," said study author Dr.Yu-Xiao Yang, an assistant professor of medicine and epidemiology. "In addition,...

The biggest study ever of calcium and vitamin D supplements for older women showed they offered only limited protection against broken bones, raising questions over what has been an article of faith among doctors and nutritionists. The supplements seemed to reduce the risk of broken hips in women over 60 and also helped those who took the supplements most regularly. But as to preventing bone fractures overall, vitamin D and calcium flunked in these healthy women. One of the researchers, Dr. Norman Lasser at New Jersey Medical School, said the study is "not as ringing an endorsement of calcium as...

Anyone concerned about their bones is likely to make sure they have plenty of vitamin D, either by getting enough sunshine, eating fish, or taking supplements. Yet scientists know surprisingly little about how the compound works. A new study has finally shed some light on this process, showing how the vitamin takes part in a delicate balancing act between cells that tear down our bones and cells that rebuild them. Vitamin D is a familiar player in bone health. Without sufficient amounts of this hormone, our frames become frail with disorders such as osteoporosis or rickets. But vitamin D has...

You might expect that a stronger cage is always better. But the power of a new chemical cage announced this week lies in its weakness: It's about 100 times more efficient at releasing its prisoner than its widely used counterparts. The flimsy molecular pen may help map the brain's chemical circuitry and decipher the signals that control the beating heart. One way to study how cells function is to control the availability of a particular biomolecule by encapsulating it in a chemical box until a flash of light sets it free. Researchers have used this strategy to probe how cells...

By THE ASSOCIATED PRESS ORLANDO, Fla. (AP) -- Getting a little sunshine may be one way for men to cut their risk of prostate cancer. A large study presented at a cancer conference Thursday found that men with higher levels vitamin D in their blood were half as likely to develop aggressive forms of the disease than those with lower amounts. Doctors are not ready to recommend the ``sunshine vitamin'' without more study, but many see little harm in getting the 15 minutes a day that the body needs to make enough of this nutrient. ``When you were little and...

A widely used antibiotic long considered safe dramatically increases the risk of cardiac arrest, particularly when taken with some popular drugs for infections and high blood pressure, a huge study found.The drug is erythromycin, which has been on the market for 50 years and is prescribed for everything from strep throat to syphilis. The new study shows the need for continuing research on the safety of older medicines, including how they interact with newer drugs, said researcher Wayne A. Ray, a professor of preventive medicine at Vanderbilt University School of Medicine in Nashville.In patients taking erythromycin along with other drugs...

Huge moves recently. It was 5/6 Bush or .88/1,now its 4/6 and .69/1 Blue and pink shading show recent movements (Probably the past day).

PERSONAL HEALTH Evolution is an excellent teacher when it comes to figuring out what and how much people should eat. For example, primates (including those with two legs and big brains) evolved on foods rich in potassium and very low in sodium. Early humans evolved to conserve sodium, which was hard to obtain, and to excrete excess potassium, abundant in many fruits and vegetables. But Western-style diets these days are the reverse of what those early humans consumed, rich in processed foods, loaded with sodium and relatively poor in potassium. Consequently, according to a report released this year by the...

(my emphasis added) FTC Stops Infomercial Claiming Cures The Associated Press CHICAGO June 13 — A federal judge Friday ordered a marketing company to stop airing an infomercial that claims a calcium supplement can cure diseases including heart disease and cancer, an attorney for the Federal Trade Commission said. The FTC is also seeking restitution for customers. Shop America was ordered to stop airing infomercials promoting a supplement made from dead marine coral. The order also bars Kevin Trudeau, ShopAmerica's owner, from access to the company's funds until a trial determines potential restitution, said Heather Hippsley, assistant director of...