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Keyword: endostatin

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  • Tumor Blocker May Fight Fibrosis

    05/30/2012 10:29:17 PM PDT · by neverdem · 7 replies
    ScienceNOW ^ | 30 May 2012 | Mitch Leslie
    Enlarge Image Thick-skinned. Fragments of the anticancer drug endostatin can halt fibrosis in a slab of human skin. Credit: Feghali-Bostwick Laboratory Connective tissue holds our bodies together, but in a condition called fibrosis, an overabundance of the material devastates organs such as the liver, heart, and lungs. A new study suggests that fragments of a promising cancer drug can rein in fibrosis, which is currently untreatable. Fibrosis occurs when cells pump out excess collagen and other connective tissue proteins, which harm organs. Pulmonary fibrosis, for example, stiffens the lungs, eventually suffocating patients unless they receive a lung transplant. In...