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The drug atogepant may help prevent migraines for people who have had no success with other preventive drugs, according to a preliminary study. The study involved people with episodic migraine, which is defined as having up to 14 headache days per month with migraine characteristics. Atogepant is a calcitonin gene-related peptide receptor antagonist, or CGRP inhibitor. CGRP is a protein that plays a key role in starting the migraine process. "These results are exciting, as migraine can be debilitating, and this treatment led to fewer days with migraine for people who had already tried up to four other types of...

Pfizer is recalling more than four million packages of the Nurtec ODT prescription migraine medication over a risk of poisoning to children due to a failure to meet child-resistant packaging safety requirements. The company is recalling around 4.2 million units of Nurtec ODT (rimegepant) 75mg orally disintegrating tablets, which are sold in packs of eight doses on a blister card, on Thursday, the U.S. Consumer Product Safety Commission said. Anyone affected will be able to obtain a free child-resistant pouch to store the product, the commission said.

In a study Professor Dale Nyholt and QUT Ph.D. researcher Rafiqul Islam, describe using large-scale genome-wide associations studies (GWAS) summary statistics to analyze hundreds of thousands of human genomes from headache and migraine sufferers and non-sufferers. Professor Nyholt said the co-occurrence of migraine and glycemic (blood sugar levels) traits had been reported in observational epidemiological studies but it was unknown how they were genetically linked. "About 15% of the global population is affected by migraine, and as far back as 1935, migraine was described as a 'glycemic headache,'" Professor Nyholt said. "Glycemic traits such as insulin resistance, hyperinsulinemia (too much...

Increased dietary fiber intake is associated with a decreased incidence of migraine, according to a study. Hao Huang examined the association between dietary fiber intake and the prevalence of severe headache or migraine using data from the National Health and Nutrition Examination Survey (1999 to 2004). The researchers found that after adjusting for covariates, there was a significant inverse association seen between dietary fiber intake and severe headache or migraine, with the lowest prevalence observed in the fifth quintile (odds ratio, 0.74). For every 10-g/day increase in dietary fiber intake, the prevalence of severe headache or migraine decreased by 11...

Dietary niacin intake is associated with migraine among U.S. adults, with an L-shaped curve and an inflection point of about 21.0 mg/day, according to a study. Huanxian Liu, M.D. and colleagues examined the association between dietary niacin and migraine using cross-sectional data from people aged older than 20 years who participated in the National Health and Nutrition Examination Survey between 1999 and 2004. Data were included for 10,246 participants, of whom 20.1 percent experienced migraines. The researchers found that the adjusted odds ratio values for dietary niacin intake and migraine were 0.83, 0.74, and 0.72 in quartiles (Q) 2 (12.4...

Patients with migraine with aura (MwA) have significantly higher artificial intelligence-enabled electrocardiogram (AI-ECG) atrial fibrillation (AF) prediction model output, according to a study. Chia-Chun Chiang, M.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues compared AI-ECG AF prediction model output in adult patients with MwA and migraine without aura (MwoA). Adult patients with an MwA or MwoA diagnosis and at least one ECG with normal sinus rhythm within the past 20 years were identified. A total of 40,002 patients (17,840 with MwA and 22,162 with MwoA) were included in the final analysis. The researchers found that compared with the...

Something happened recently that I believe may help some people. I have had many of these ocular migraines over the last two years. I kept a diary on their occurrences on my iPhone, because I wanted to have a trend line. Suddenly they stopped. Not one in the last eight months. The scare of actual migraine headaches (curse them!) has gone to near zero. I looked back at my medical records to see what happened. Please pass this information along to any person with this problem. The only thing that changed: I had a bad tooth extracted. It was on...

Migraine sufferers soon may have to seek relief elsewhere after GlaxoSmithKline (GSK) announced it temporarily halted the production of two popular Excedrin products. In a statement sent to Fox News, the company said it was not recalling either Excedrin Extra Strength Caplets and Geltabs or Excedrin Migraine Caplets and Geltabs, but that it had discovered “inconsistencies in how we transfer and weigh ingredients” in the products, and was temporarily suspending production and distribution. “Based on available data, GSK believes that the product does not pose a safety risk to consumers,” a GSK spokesperson said via email. “However, as a precautionary...

Today show stars are fearing the axe after NBC honchos announced their secret plan for new star Megyn Kelly, RadarOnline.com has learnedKelly “wants to do a smart morning political show and wants to hire her own staff,” someone in the know tells Radar Online. “But NBC [is] pushing for more of a daytime show with an audience like Phil Donahue under the Today umbrella and staff.”

It can start with flashing lights, a tingling sensation and a feeling of unease, followed by excruciating pain. Migraines can be triggered by lack of food or too much stress but their underlying cause has remained a mystery. Now researchers have found that a migraine may be triggered by a protein deep in the brain that stimulates the neurons controlling facial sensations. The discovery creates a potential new target for safer migraine medicines and adds weight to the theory that neurons, not blood vessels, are responsible for migraine attacks. “Where a migraine starts is a key question,” says Debbie Hay...

Now two more women are coming out, accusing him, making it now up to seventeen women who have come out against him. 1) "Former comedy club manager claims Cosby gave her a Quaalude... and hours later woke up naked in his friend's bed" Read more: http://www.dailymail.co.uk/news/article-2845640/He-said-little-strong-Former-comedy-club-manager-claims-Cosby-gave-sedative-Quaalude-complained-migraine-hours-later-woke-naked-friend-s-bed.html#ixzz3JqLtCwem Follow us: @MailOnline on Twitter | DailyMail on Facebook 2) "Grandmother is latest to accuse Cosby: Former talent agent says the comedian 'drugged and attacked her during a party at his home while his wife was out of town'" Read more: http://www.dailymail.co.uk/news/article-2845566/New-Hampshire-grandmother-latest-woman-accuse-Bill-Cosby-drugging-assaulting-inviting-party-comedian-s-wife-town.html#ixzz3JqM4vklY Follow us: @MailOnline on Twitter | DailyMail on Facebook

March 27, 2009. I was fine the night before. The little cold I’d had was gone, and I’d had the first good night’s sleep all week. But when I woke up Friday morning at 6:15 and got out of bed, the world was whirling counterclockwise. I knocked against the bookcase, stumbled through the bathroom doorway and landed on my knees in front of the sink. It was as though I’d been tripped by a ghost lurking beside the bed. Even when I was on all fours, the spinning didn’t stop. Lightheaded, reaching for solid support, I made it back to...

For those who suffer from migraines, you know that they can often be debilitating. A day with a migraine is one spent hoarded up in a room, shades drawn, eyes shut tight, wishing for sleep to provide relief from the pain. Two new drug studies are changing the way that a medicine looks at treating migraines. Rather than working to stop the migraine once it has started, these drugs are aimed at preventing the migraine from occurring in the first place. Although both drugs need more studies conducted before their effectiveness can be confirmed, so far the results look promising....

The US Food and Drug Administration (FDA) today allowed marketing of the first device for the preventive treatment of migraine headaches (Cefaly, STX-Med). It is also the first transcutaneous electrical nerve stimulation (TENS) device specifically authorized for use before the onset of pain, the FDA noted in a statement released today. "Cefaly provides an alternative to medication for migraine prevention," Christy Foreman, director of the Office of Device Evaluation at the FDA's Center for Devices and Radiological Health, said in the statement. "This may help patients who cannot tolerate current migraine medications for preventing migraines or treating attacks." The device,...

In 1908, over a bowl of seaweed soup, Japanese scientist Kikunae Ikeda asked a question that would change the food industry forever: What gave dashi, a ubiquitous Japanese soup base, its meaty flavor? In Japanese cuisine, dashi, a fermented base made from boiled seaweed and dried fish, was widely used by chefs to add extra oomph to meals — pairing well with other savory, but meatless foods such as vegetables and soy. For some reason that was generally accepted but inexplicable, dashi made these meatless foods meaty — and Ikeda was determined to find out why. Ikeda was able to...

Michele Bachmann gives me a headache. But it’s not the Minnesota congresswoman herself who is to blame for the pain. It’s so many of the stories about her and her husband. See or hear her name these days and you will probably be in for some head-pounding disappointment from the story that follows. But if it was about the former governor of Minnesota worming his way out of a comment that was beneath him, at least that was an improvement over the week before and the outrageous you’re-so-gay dance led by MSNBC. (If only it were The Last Word.) That’s...

Bachmann Migraine Story Underscores Lingering Stigma Nancy A. Melville July 22, 2011 — In a summer of unusually heated political turmoil and mudslinging from both sides of the aisle, the medical issue that has unexpectedly become caught in the crossfire seems somehow appropriate — migraines, and specifically, Rep. Michele Bachmann's migraines.The GOP presidential candidate's migraines became big news this week following a report on the Daily Caller Web site that an adviser to Representative Bachmann (R-Minnesota) said the congresswoman suffers from "intense" migraines, that when she gets them "she can't function at all," and she "takes all sorts of pills" for...

News-futures website Intrade...Mr. Perry’s nomination odds reached a high of 33 percent Thursday morning, eclipsing Mr. Romney for the first time. Mr. Romney, trading at 32 percent,..... Mrs. Bachmann’s odds have dropped from highs of 22 percent a few days ago to slightly less than 10 percent after a report by the Daily Caller revealed that she suffered from debilitating migraines.... Bettors give President Obama a 57 percent chance of getting re-elected

JACKSON, Miss. - Treating chronic migraines with behavioral approaches - such as relaxation training, hypnosis and biofeedback - can make financial sense compared to prescription-drug treatment, especially after a year or more, a new study found. Longtime behavioral therapy researcher and practitioner Dr. Donald Penzien, University of Mississippi Medical Center professor of psychiatry, coauthored the study. He said the costs of prescription prophylactic drugs - the kind chronic migraine sufferers take every day to prevent onset - may not seem much even at several dollars a day. "But those costs keep adding up with additional doctor visits and more prescriptions,"...

Every one of us has a mysterious double life. For about two thirds of the time we are conscious beings, thinking about the world within and without, and negotiating our ways through the obstacles of life. For the other one third of the time we are nearly lifeless lumps of flesh, unconscious to everything but our own fantasies, as we lie flat in bed asleep. We all know that sleep is important for health. But for an activity that consumes about 8 hours of everyday of life, surprisingly little is thought about the act of sleeping, or the way our...