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Keyword: oncology

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  • Researchers discover gene that permanently stops cancer cell proliferation

    08/08/2012 12:28:15 PM PDT · by Red Badger · 16 replies
    Medical Express ^ | 08-01-2012 | Provided by Case Western Reserve University
    Researchers at Case Western Reserve University School of Medicine have discovered a mutant form of the gene, Chk1, that when expressed in cancer cells, permanently stopped their proliferation and caused cell death without the addition of any chemotherapeutic drugs. This study illustrates an unprecedented finding, that artificially activating Chk1 alone is sufficient to kill cancer cells. "We have identified a new direction for cancer therapy and the new direction is leading us to a reduction in toxicity in cancer therapy, compared with chemotherapy or radiation therapy," said Dr. Zhang, assistant professor, Department of Pharmacology at the School of Medicine, and...
  • Doctors call for end to five cancer tests, treatments

    04/04/2012 8:32:34 AM PDT · by jakerobins · 19 replies
    NEW YORK (Reuters) - In a move that threatens to further inflame concerns about the rationing of medical care, the nation's leading association of cancer physicians issued a list on Wednesday of five common tests and treatments that doctors should stop offering to cancer patients. The list emerged from a two-year effort, similar to a project other medical specialties are undertaking, to identify procedures that do not help patients live longer or better or that may even be harmful, yet are routinely prescribed
  • New leukemia treament exceeds 'wildest expectations'

    08/10/2011 1:39:34 PM PDT · by Nachum · 68 replies
    NBC News ^ | 8/10/11 | Robert Bazell
    Doctors have treated only three leukemia patients, but the sensational results from a single shot could be one of the most significant advances in cancer research in decades. And it almost never happened. In the research published Wednesday, doctors at the University of Pennsylvania say the treatment made the most common type of leukemia completely disappear in two of the patients and reduced it by 70 percent in the third. In each of the patients as much as five pounds of cancerous tissue completely melted away in a few weeks, and a year later it is still gone
  • Sam I Am (vanity)

    09/11/2006 4:37:59 AM PDT · by NonLinear · 20 replies · 760+ views
    A letter from Lee Metz | 9/11/2006 | Lee Metz
    Hello Everybody, Over the past 7 ½ years I have written a couple of times to tell you stories about my son’s battle with cancer. I now have one last story to tell. And I want you to hear it. This last story begins with a boat. The boat is not much to look at anymore because it has aged a lot since the day it was built. I am sure a boat of this size had a name but I can’t find it anywhere, and it has been painted so many times that the original color is no longer...
  • Beth Israel is armed for precision surgery, Newark hospital gets latest robotics system

    08/16/2006 9:50:34 PM PDT · by Coleus · 3 replies · 237+ views
    Star Ledger ^ | 08.15.06 | ANGELA STEWART
    There's a new da Vinci in town -- but this one is devoted to the surgeon's art. Newark Beth Israel Medical Center is opening its Robotic Training Center, featuring the new $1.5 million da Vinci S Surgical System. The new system allows for greater precision in performing minimally invasive operations. Doctors from all over the world are expected to train at the center -- one of only three sites in the country to have the latest da Vinci robot. The other two are The Methodist Hospital in Houston, affiliated with the Weill Medical College of Cornell University, and the Sunnyvale,...
  • A Cancer Drug's Big Price Rise Disturbs Doctors and Patients

    03/11/2006 12:57:14 PM PST · by Racehorse · 62 replies · 1,850+ views
    New York Times ^ | 12 March 2006 | Alex Berenson
    On Feb. 3, Joyce Elkins filled a prescription for a two-week supply of nitrogen mustard . . . The cost was $77.50. On Feb. 17, Ms. Elkins, a 64-year-old retiree . . . returned to her pharmacy for a refill. This time . . . the cost was $548.01. Ms. Elkins's insurance does not cover nitrogen mustard, which she must take for at least the next six months at a cost that will now total nearly $7,000. She and her husband . . . are paying for the medicine by spending less on utilities and food, she said. The medicine...
  • WSJ: Pazdur's Cancer Rules - The FDA's oncology chief gets his revenge.

    07/06/2005 5:02:16 AM PDT · by OESY · 9 replies · 1,484+ views
    Wall Street Journal ^ | July 6, 2005 | Editorial
    ...FDA oncology drugs chief Richard Pazdur is the most important person in the U.S. government when it comes to cancer drugs, and he has never made a secret that he dislikes the accelerated approval process under which Iressa got the green light. Nor has he been shy about suggesting that the agency was railroaded in this drug's case. The truth is that Iressa-maker AstraZeneca simply refused to play by Dr. Pazdur's rules. In 2002 -- knowing it had plenty of data to qualify for accelerated approval -- the company rebuffed his requests for more trials and appealed directly to something...
  • WSJ: The FDA vs. Cancer Patients -- Drugs that save lives belong on the market

    05/19/2005 5:39:10 AM PDT · by OESY · 1 replies · 348+ views
    Wall Street Journal ^ | May 19, 2005 | Editorial
    ...Former FDA Commissioner Mark McClellan made some progress moving the agency to speed up the drug approval process. But he was pulled away to run Medicare, and agency bureaucrats have since been working feverishly to turn back the clock. The latest evidence of backsliding was a recent vote of the Oncologic Drugs Advisory Committee (ODAC) to recommend against approving Johnson & Johnson's leukemia drug Zarnestra.... This is a special shame because ODAC used to be a bastion of common sense, wherein clinicians who treat cancer patients would often buck FDA statisticians to approve new drugs. But ODAC is now chaired...
  • God at the Bedside [Medical practice and religion]

    03/18/2004 8:52:09 AM PST · by Pharmboy · 5 replies · 197+ views
    New England Journal of Medicine ^ | March 18, 2004 | Jerome Groopman, M.D.
    Not long ago, in the oncology clinic where I work, my patient Anna Angelo asked me to pray to God. At the time, prayer was far from the forefront of my mind. Anna (her name has been changed to maintain confidentiality) is a 71-year-old woman from Boston's North End with long-standing cardiac and hepatobiliary disease. Six years ago, breast cancer developed. The tumor was incurable from the time of diagnosis, since it had already spread to bone. The cancer cells tested positive for estrogen and progesterone receptors, and Anna was treated with a series of hormonal agents, which, over the...
  • A Debate on Radiation in Breast Cancer

    02/24/2004 4:33:25 PM PST · by neverdem · 2 replies · 246+ views
    NY Times | February 24, 2004 | LAURIE TARKAN
    Radiation treatment is being prescribed for more and more breast cancer patients, including women who would have been told just a few years ago that they could skip it. The added therapy mostly affects those women who are treated with mastectomy and chemotherapy, and have fairly good prognoses at what is called Stage 2 cancer. But cancer experts and doctors are divided over whether these women really need radiation to improve their chances of survival. For some, radiation may enhance their prospects of preventing a recurrence of their breast cancer. But whether that translates into increases in the chances for...
  • "The Reagan Years Legitimized Bigotry"--Barbra Streisand

    10/25/2003 5:42:34 AM PDT · by freedom4me · 121 replies · 342+ views
    The Advocate is a national gay and lesbian magazine. Here's what Barbra had to say in their August 17, 1999 issue: "The Reagan years legitimized bigotry. AIDS, which even then affected as many if not more heterosexuals than homosexuals throughout the world, was dismissed as a gay disease with an official homophobic wink, implying that those deaths did not matter because of who was involved.... We are filled with the hope that someday, some way, we will see an end to this human tragedy, but the battle is far from won, and there is a long road still ahead."