Free Republic

Since the discovery of hallmark features of senescence such as cell cycle arrest, apoptosis resistance and development of a senescence-associated secretory phenotype (SASP), efforts in understanding how senescent cells drive aging have grown exponentially. Targeting senescent cells with senolytics or senomorphics hold the potential to mitigate the vast majority of age-related disorders. However, the major challenge in developing novel senotherapies is the paucity of antiaging agents that have decent safety profiles. Prof. Sun Yu recently performed large scale screening of a natural medicinal agent library for senotherapeutic candidates and validated several agents, which showed their excellent potential to serve as...

SÃO PAULO, July 16, 2020 /PRNewswire/ -- The growing demand for healthiness and products that help support the immune system is expanding the use of botanical ingredients in the global market. The powerful antioxidant effect of quercetin and rutin has brought these bioactive compounds to the forefront, especially for application in food supplements of natural origin. According to research by the Nielsen market intelligence agency on the impact of the Covid-19 pandemic, consumers are prioritizing products that help them protect their health, particularly those that offer immunity benefits.