Posted on 12/27/2021 4:16:45 PM PST by SeekAndFind
The Substack Modern Discontent recently posted an anthology series on the benefits of quercetin, including the finding that it works like hydroxychloroquine, a drug found to be effective against SARS-CoV-2 when used early enough.
Part 1 begins with a brief overview of what quercetin is and its basic mechanisms of action. Quercetin is a flavonoid found in a variety of fruits and vegetables, such as onions and shallots, apples, broccoli, asparagus, green peppers, tomatoes, red leaf lettuce, strawberries, raspberries, blueberries, cranberries, black currants and green tea.
The quercetin content in any given food is largely dependent on light exposure, though, so depending on the country you’re in, different foods will top the list of most quercetin-rich.
Quercetin modulates NLRP3 inflammasome, an immune system component involved in the uncontrolled release of proinflammatory cytokines that occurs during a cytokine storm.
For example, quercetin has been shown to:
“Although [a] computer modeled study, the evidence here suggests that quercetin’s binding activity to ACE2 is comparable to other standard of care drugs used to treat SARS-CoV-2 (eg. Remdesivir, Lopinavir, Ritonavir).”
In Part 3, Modern Discontent reviews some of the clinical trials that have taken place. One COVID-19-specific study found that people who took zinc and two zinc ionophores — quinine drops and quercetin — had lower incidence of COVID-19 than the control group. Over the course of the study (20 weeks), only two of the 53 test subjects became symptomatic, compared to 12 of the 60 controls. As noted by Modern Discontent:
“Although this didn’t test quercetin in isolation, the study does suggest that over-the-counter, easily accessible compounds may be extremely beneficial in fighting against COVID, especially when taken as a prophylactic.”
In another trial, 76 outpatients who tested positive but had only mild symptoms were given 1,000 mg of Quercetin Phytosome® (quercetin in sunflower phospholipids that increase oral absorption 20-fold) per day for 30 days, in addition to standard care (analgesics, oral steroids and antibiotics). Another 76 patients were given standard of care only.
In the quercetin group, only 9.2% of participants went on to require hospitalization, compared to 28.9% of patients who received standard of care only. According to the authors:
“The results revealed a reduction in frequency and length of hospitalization, in need of non-invasive oxygen therapy, in progression to intensive care units and in number of deaths.
The results also confirmed the very high safety profile of quercetin and suggested possible anti-fatigue and pro-appetite properties. QP [Quercetin Phytosome®] is a safe agent and in combination with standard care, when used in early stage of viral infection, could aid in improving the early symptoms and help in preventing the severity of COVID-19 disease.”
Quercetin was also featured in two scientific reviews published in 2020. The first, published in in the Integrative Medicine journal in May 2020,32 highlighted quercetin’s promotion of SIRT2, which inhibits NLRP3 inflammasome.
The second review article, published in the June 19, 2020, issue of Frontiers in Immunology, highlighted quercetin’s usefulness as a COVID-19 treatment when used in conjunction with vitamin C. The vitamin C recycles oxidized quercetin, producing a synergistic effect. It also enhances quercetin’s antiviral capacity.
With the advent of processed foods, many important nutrients have been lost or minimized in the average person’s diet. Quercetin, being found in fresh fruits, vegetables and berries is one of them. Unfortunately, while essential vitamins and minerals are generally recognized for their importance, antioxidants such as quercetin are often overlooked, and sometimes labeled as “pseudoscience” or “fad” supplements. As noted by Modern Discontent:
“The great number of benefits that these compounds contribute to humans cannot be overstated … An argument can be made that not only could quercetin prove beneficial to our health, but an absence of it may prove detrimental in the long term.”
If COVID-19 has taught us anything, it’s the importance of basic health and a healthy immune function. In this regard, a diet high in fresh fruits and vegetables can go a long way. Nutritional supplements also have their place, especially in situations like a pandemic.
In conclusion, Modern Discontent provides the following summary of findings:
• “There’s evidence that quercetin may work similarly to hydroxychloroquine — It seems that quercetin may operate as both an immunomodulator and a zinc ionophore. Its use as an over-the-counter anti-allergic supplement as well as its use for asthma indicates an ability to affect the production of histamine and cytokines …
• Quercetin has plenty of other benefits — … Antioxidants … are some of the most well studied compounds, with possible anti-cancer, pro-heart and pro-organ benefits. Add on possible antimicrobial properties and it becomes hard to argue that this is nothing more than a possible fad supplement.
• Although limited, there is some evidence that quercetin may be effective against SARS-CoV2 — Computer models and in vitro studies suggest that ACE2 receptors and the main protease of SARS-CoV2 may be good target candidates for quercetin … the limited number of studies suggest quercetin may be effective, especially if used early on or as a prophylactic.
• Dietary quercetin is the main source of quercetin, and its deficiency in modern diets may be contributing to our health problems — Quercetin is primarily sourced from colorful fruits, vegetables, teas … all foods that many of our ancestors would have consumed on a regular basis … Modern ‘enriched’ foods tend to supplement with additional vitamins and minerals, but may miss out on other plant-derived compounds that have played a substantial role in our diet.
Similar to reduced sunlight exposure and the need for increased vitamin D supplementation, we may need to look at possible supplementation of overlooked compounds such as polyphenols. Sourcing these compounds from real foods would prove the most beneficial, but in groups of people who may not have access to fresh fruits and vegetables, quercetin and polyphenol supplementation may be useful.
This would include people with alternative diets such as keto, who may avoid high carb fruits, and thus may be missing a key nutrient in their diets.
Quercetin has plenty of benefits, and for those who may be missing out on it in their diet they may want to look into sourcing it with supplementation. Don’t take this as a prescription or recommendation, but an argument to examine your own health and see what you may be lacking …”
>My vitamin regimen is so strong, nothing can penetrate it.
>I’m even thinking about picking up some bad habits I left off years ago.
Same here, picked up smoking cigars again
Been taking the Amazon one daily for almost a year now. Along with Vitamins B, C and D.
Worried that the tyrants will ban it.
Right at the beginning of this crap, I and another Freeper we’re discussing ‘this. I said I got the zinc,C, and D down pat. He said add Quercetin I did. Ain’t hurt me and I don’t give a damn about the common cold or flu or the China BS. I’m 70 and ain’t stayed at Holiday Inn. LGBFJB 👌
The thing to remember about quercetin is low bioavailability and short half life. When I had the ‘rona I took it about 5 times a day with a zinc supplement in the evening.
RE: When I had the ‘rona I took it about 5 times a day with a zinc supplement in the evening.
So, do you think it worked for you?
RE: Where do you get it?
It’s available in every Vitamin shop.
“Bromelain” is in Pineapple and is mixed with salt in Adolph’s Meat Tenderizer.
bkmk
Yeah but you cant get enough just from a little pineapple.
You need it as a supplement, and for it to work the way you want it to for illness, take it on an empty stomach.
bttt
Well my doctor gave me a series of drugs including steroids. I took palmitoylethanolamide for neuroinflammation and quercetin/zinc to inhibit viral replication. My fever only lasted four days, No respiratory problems. Symptoms were very mild compared to the flu.
I dont believe that is true. Bromelain is supposed to have anti-inflammatory properties and assist in the absorption of C but is not a zinc ionophore itself.
Apparently most people have no problem with bromelain. Ive noticed in the past that I seem to be sensitive to things derived from pineapple concentrates. My initial attempts to supplement my quercetin went really very wrong. Among those things were increased joint pain and large strange very painful abscess like pillows forming in my mouth nearly pushing out my lower incisors. This is when I realized that the quercetin I had purchased contained bromelain. I should have known better.
If a person cant find quercetin by itself and they are pineapple sensitive then I would think that increasing natural sources may be a better choice. I cant prove it but can offer this, my diet compared to the average person is likely significantly higher in onions, apples, blueberries, and cranberries. I drink coffee at work but tend to prefer tea at home and I drink a lot of it.
Someone I was in direct contact with on a daily basis came and stayed in my home when they brought the Alpha cooties from Spain. I didnt catch the cooties or at least had no symptoms.
During the “we all gonna dah” plague of Delta I worked “unprotected” doing direct care in an apartment building full of people that all supposedly had cooties. I didnt catch the cooties or at least had no symptoms.
The super duper transmissible and certain to get you variant arrived in my home nearly two weeks ago. I didnt catch the cooties or at least had no symptoms.
Im an aging, overweight, chain smoking, nevervaxxx, diabetic. Im certain to have died several times by now. Except that where I was working it was the young modern diet sit in the basement and play video game vaxxxed kids that all caught the cooties. In fact, it was only aging, overweight, chain smoking, diabetic, notavaxxx resistant management personnel that showed up every day to fill those empty slots in the schedule without themselves having any symptoms or missing a day.
Of course there are other dietary elements (D) that are much higher in an local older rural persons diet than what the kids get that may play a big part and we tend to spend more time outside collecting D. That likely plays a big part of it too.
I guess all I know for sure is that the government and the plants on this forum are lying. The only people Ive seen get severely ill from cooties (the diagnosis itself highly questionable) are those that have been subjected to the notavaxxx.
THANK YOU - so very much - for making SURE that the article you posted was well formatted.
That is not totally easy, and I appreciate your efforts.
I will look into this chemical further.
Mark
And Thank you 😇
BTTT
We took 250mg twice daily (QBCPlex: quercitin, vitamin c and bromelain) with 50 mg zinc /copper when we had it. Got thru it pretty well.
Been on Quercetin for 2 years now with C, D3, Zinc and NAC, 2 fricking years NEVER missing a day!!
Optimized Quercitin.
Life Extension
We’ve had quercitin/C on hand since February 2020. I credit primarily quercitin/zinc/vit D with my mild case of Covid in the winter of 2021. My husband and I were exposed to omicron last week, so we’ve boosted our anti-viral supplements. We both feel some mild discomforts which we assume are from the virus trying to gain a foothold. We’re not worried and figure that a mild omicron episode just burnishes our immunity. At this point he’s had alpha, I’ve had beta, and we’re both now fending off omicron. We take some other supplements, but these are the ones I never skip.
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