btw, Dr Zalenko has a record of successfully treating hundreds/thousands with his "Z-pack".
You can purchase direct with all ingrediants in one capsule or simply the ingredients/vitamins individually...which is what I've done.
Posted on 12/27/2021 4:16:45 PM PST by SeekAndFind
The Substack Modern Discontent recently posted an anthology series on the benefits of quercetin, including the finding that it works like hydroxychloroquine, a drug found to be effective against SARS-CoV-2 when used early enough.
Part 1 begins with a brief overview of what quercetin is and its basic mechanisms of action. Quercetin is a flavonoid found in a variety of fruits and vegetables, such as onions and shallots, apples, broccoli, asparagus, green peppers, tomatoes, red leaf lettuce, strawberries, raspberries, blueberries, cranberries, black currants and green tea.
The quercetin content in any given food is largely dependent on light exposure, though, so depending on the country you’re in, different foods will top the list of most quercetin-rich.
Quercetin modulates NLRP3 inflammasome, an immune system component involved in the uncontrolled release of proinflammatory cytokines that occurs during a cytokine storm.
For example, quercetin has been shown to:
“Although [a] computer modeled study, the evidence here suggests that quercetin’s binding activity to ACE2 is comparable to other standard of care drugs used to treat SARS-CoV-2 (eg. Remdesivir, Lopinavir, Ritonavir).”
In Part 3, Modern Discontent reviews some of the clinical trials that have taken place. One COVID-19-specific study found that people who took zinc and two zinc ionophores — quinine drops and quercetin — had lower incidence of COVID-19 than the control group. Over the course of the study (20 weeks), only two of the 53 test subjects became symptomatic, compared to 12 of the 60 controls. As noted by Modern Discontent:
“Although this didn’t test quercetin in isolation, the study does suggest that over-the-counter, easily accessible compounds may be extremely beneficial in fighting against COVID, especially when taken as a prophylactic.”
In another trial, 76 outpatients who tested positive but had only mild symptoms were given 1,000 mg of Quercetin Phytosome® (quercetin in sunflower phospholipids that increase oral absorption 20-fold) per day for 30 days, in addition to standard care (analgesics, oral steroids and antibiotics). Another 76 patients were given standard of care only.
In the quercetin group, only 9.2% of participants went on to require hospitalization, compared to 28.9% of patients who received standard of care only. According to the authors:
“The results revealed a reduction in frequency and length of hospitalization, in need of non-invasive oxygen therapy, in progression to intensive care units and in number of deaths.
The results also confirmed the very high safety profile of quercetin and suggested possible anti-fatigue and pro-appetite properties. QP [Quercetin Phytosome®] is a safe agent and in combination with standard care, when used in early stage of viral infection, could aid in improving the early symptoms and help in preventing the severity of COVID-19 disease.”
Quercetin was also featured in two scientific reviews published in 2020. The first, published in in the Integrative Medicine journal in May 2020,32 highlighted quercetin’s promotion of SIRT2, which inhibits NLRP3 inflammasome.
The second review article, published in the June 19, 2020, issue of Frontiers in Immunology, highlighted quercetin’s usefulness as a COVID-19 treatment when used in conjunction with vitamin C. The vitamin C recycles oxidized quercetin, producing a synergistic effect. It also enhances quercetin’s antiviral capacity.
With the advent of processed foods, many important nutrients have been lost or minimized in the average person’s diet. Quercetin, being found in fresh fruits, vegetables and berries is one of them. Unfortunately, while essential vitamins and minerals are generally recognized for their importance, antioxidants such as quercetin are often overlooked, and sometimes labeled as “pseudoscience” or “fad” supplements. As noted by Modern Discontent:
“The great number of benefits that these compounds contribute to humans cannot be overstated … An argument can be made that not only could quercetin prove beneficial to our health, but an absence of it may prove detrimental in the long term.”
If COVID-19 has taught us anything, it’s the importance of basic health and a healthy immune function. In this regard, a diet high in fresh fruits and vegetables can go a long way. Nutritional supplements also have their place, especially in situations like a pandemic.
In conclusion, Modern Discontent provides the following summary of findings:
• “There’s evidence that quercetin may work similarly to hydroxychloroquine — It seems that quercetin may operate as both an immunomodulator and a zinc ionophore. Its use as an over-the-counter anti-allergic supplement as well as its use for asthma indicates an ability to affect the production of histamine and cytokines …
• Quercetin has plenty of other benefits — … Antioxidants … are some of the most well studied compounds, with possible anti-cancer, pro-heart and pro-organ benefits. Add on possible antimicrobial properties and it becomes hard to argue that this is nothing more than a possible fad supplement.
• Although limited, there is some evidence that quercetin may be effective against SARS-CoV2 — Computer models and in vitro studies suggest that ACE2 receptors and the main protease of SARS-CoV2 may be good target candidates for quercetin … the limited number of studies suggest quercetin may be effective, especially if used early on or as a prophylactic.
• Dietary quercetin is the main source of quercetin, and its deficiency in modern diets may be contributing to our health problems — Quercetin is primarily sourced from colorful fruits, vegetables, teas … all foods that many of our ancestors would have consumed on a regular basis … Modern ‘enriched’ foods tend to supplement with additional vitamins and minerals, but may miss out on other plant-derived compounds that have played a substantial role in our diet.
Similar to reduced sunlight exposure and the need for increased vitamin D supplementation, we may need to look at possible supplementation of overlooked compounds such as polyphenols. Sourcing these compounds from real foods would prove the most beneficial, but in groups of people who may not have access to fresh fruits and vegetables, quercetin and polyphenol supplementation may be useful.
This would include people with alternative diets such as keto, who may avoid high carb fruits, and thus may be missing a key nutrient in their diets.
Quercetin has plenty of benefits, and for those who may be missing out on it in their diet they may want to look into sourcing it with supplementation. Don’t take this as a prescription or recommendation, but an argument to examine your own health and see what you may be lacking …”
But I'm also aware that there are other potential early treatments like IV NAC to prevent oxidative stress. Did your PubMed articles discuss oxidative stress as the root cause of the other problems you listed?
Let me ask you this: is trying to stop the virus from bonding to ACE2 receptors via a vaccine the only approach, or is it feasible to let the virus bond to the ACE2 receptors (don't vax) and instead treat the oxidative stress to give the body time to fight the virus off on its own before the cell damage can proliferate?
Why can't we treat people with early symptoms with IV Glutathione and keep the antioxidant levels in line with the free radicals so the harmful free radicals don't have a chance to do the damage that you cited?
Remember, we're talking about a virus with a 99% survivability rate with this treatment. We're talking about a virus that is most deadly in the oldest populations that highly correlates with Glutathione deficiencies.
Given that, what's wrong with focusing on letting the younger, stronger people wait for symptoms and then treat the oxidative stress, and then give the seniors NAC or other Glutathione precursor supplements to boost their own levels prior to getting COVID-19, and then treat the oxidative stress that follows?
-PJ
“Can you see why people might be joking that Quercetin might be next “
Well they are talking about quercetin and not NAC and don’t appear to be joking.
Quercetin is a food product and onions, esp red onions, are a particularly rich source. You don’t have to use supplements to get it. You don’t have to use supplements to get zinc either. It’s that simple.
People here with their hair on fire all afraid that quercetin can be banned ought to try reading up on where flavonoids and minerals are found naturally for once in their life.
I take Quercetin, too, so I know what it is.
Let's talk about NAC. It's a precursor to Glutathione. So is Sulforaphane. The concern about NAC and Glutathione Reduced supplements is that they are not bioavailable; they are mostly destroyed in the digestive process before they get into the bloodstream.
Sulforaphane is made from broccoli sprouts and other cruciferous vegetables and is bioavailable, so some have suggested that it's better than taking Glutathione Reduced (which might also not have a good shelf life).
I recently saw a video from a New Zealand doctor who cited studies suggesting one needs to take at least 1.2g of NAC twice a day to get past the bioavailability hurdle in order to be effective. That's two 600mg capsules, twice a day. Here's the link to this doctor's discussion: Dr. Brad Stanfield - NAC (& Glutathione) Crucial New Research.
We've been doing the same.
I thought the same thing since I haven’t had any illness in years but damned if something didn’t get me starting on the 23rd. It’s either a bad cold, mild flu or “omicron”. I was getting a bit too confident. This is probably some gain of function schit that’s been released on the public imo. Biden just threatened the unvaxxed just the other day. Be on the lookout for more bioweapons being released to cull the population along with the so called vaccine. This might just be a trial run since it isn’t too deadly.
“I thought the same thing since I haven’t had any illness in years but damned if something didn’t get me starting on the 23rd. It’s either a bad cold, mild flu or “omicron”. I was getting a bit too confident. This is probably some gain of function schit that’s been released on the public imo. Biden just threatened the unvaxxed just the other day. Be on the lookout for more bioweapons being released to cull the population along with the so called vaccine. This might just be a trial run since it isn’t too deadly.”
*****
Omicron is a really good candidate, they are saying it will peak in the US around Jan9 in terms of infections, with somewhere around 60% of the population having caught it, which is a little crazy when you remember we just heard about it at Thanksgiving.
One of my tin foil hat crock pot speculations is that maybe the BioWars have begun, and Omicron is a floating vaccine for Covid release by the good guys.
We’ll see what happens, sure would be nice to have some people and institutions we could trust, wouldn’t it?
Thanks for the advice. I take it from your comments that unlike hydroxychloroquine and ivermectin, which you have to buy on the black market, quercetin seems to be readily available.
btw, Dr Zalenko has a record of successfully treating hundreds/thousands with his "Z-pack".
You can purchase direct with all ingrediants in one capsule or simply the ingredients/vitamins individually...which is what I've done.
RE: U take it from your comments that unlike hydroxychloroquine and ivermectin, which you have to buy on the black market, quercetin seems to be readily available.
Absolutely. I buy mine from The Vitamin Shoppe. It is headquartered in New Jersey and has nearly 800 franchise locations nationwide.
See here:
https://www.vitaminshoppe.com/
But there are many more competing Vitamin stores all over the country. You should be able to get Quercetin from them. Competition is good. It makes the price affordable.
You have somehow stumbled onto wrong information.
Quercetin is an ionophore, enabling entry of zinc into the cells where it inhibits viral replication.
Quercetin and zinc are a cure for the common cold.
The vitamin D is a major prevention for coronavirus. Keep your level above 50.
which is what brand?
I have 250 grams of it, well probably about 210 grams left.
Take it regularly.
I’ll sell it to you for a mere $15 a gram...
(Actually, it’d save you a few bucks if you search for Bulksupplements on Google)
what’s a good quality brand of NAC? I think the last one (and only) that I bought was NOW brand and I feel awful when I take it. Very depressed feeling and as soon as I stopped taking it I pop back up
Look up Nano Quercetin on Amazon.
-PJ
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.