Forgive me for asking, but how do you know it is not the placebo effect?
Same way I know a decongestant opening my nasal passages is not a placebo effect. It is obvious.
After about 10 days my wife noticed I was singing in the shower for the first time in a couple years. She noticed the change before I did.
And many times you are taking the drugs just to please someone else not in any real hope of improvement.