Dont forget 50 Beowulf if you want to a big hole in something like a brown Bear charging you or perhaps .458 Socom. I had a .458 Socom upper for a while and with a 330 grain punch bullet it penetrated 50 inches of wet newspaper and stuck in the wood behind it at a John Linebaugh seminar.
I like all those cartridges. I think I’m going to go Wolverine on my next project.