Posted on 10/11/2010 8:51:51 PM PDT by Pining_4_TX
Now, for the first time, researchers are using diabetes and "cure" in the same sentence.
Doctor Donald Jump at Oregon State University eliminated diet-induced diabetes -- or type two diabetes -- in lab mice.
"We saw that certain enzymes were being repressed by the high-fat diet," Donald Jump, Ph.D., department of nutrition and exercise sciences, said.
The enzyme he's talking about is called fatty acid elongase-five. The more fat we eat, the less of the enzyme we produce. So, when researchers boosted the production of the enzyme in mice livers, they were cured of their diabetes in five days.
"The animals hyperglycemia disappeared, and their fatty liver disappeared, and their insulin resistance disappeared. We were very dazzled by this outcome," Dr. Jump added.
(Excerpt) Read more at ivanhoe.com ...
ping
Well....maybe that’s why when I eat more fat and protein I feel better....and I’m NOT hungry.....diabetes runs in my family (Type 2) and I think it’s related to eating too many carbs, not enough fat/protein....some people just don’t need so many carbs....
follow the atkins diet. It too has the same effect on type 2 diabetes.
You might state clearly that this is another potential treatment for TYPE II or adult-onset diabetes not insulin-dependent Type I diabetes.
The kind of diabetes you give yourself from being morbidly obese. Hint, try losing the weight first and see if that doesn’t clear things up.
It’s bee said by some nutritional gurus that our obesity epidemic has a lot to do with the “low-fat” craze. Human beings need “good fats” in their diet. Without it, we just stuff ourselves with low-quality carbs and turn into plumpers.
I feel better when I use insulin because it lowers my blood sugar ~ which simply goes off the charts if I don't use insulin. (This is that inbetween 1 and 2 deal where you get to suffer the symptoms of both ~ obviously an immunological disease)
Still, this makes sense ~ a missing enzyme causes problems. Think about it in a state of nature. You are out there eating wild game and berries. You have little or no starch or sugar in your diet. That's gotta' drop your blood sugar below normal UNLESS, perhaps, the body suppresses production of that enzyme.
Later, in Summer, when there's plenty of sugar around, you eat less game, sit around the camp and grow fat and lazy, and the enzyme comes back to control your blood sugar levels.
Meat in winter; taters in the summer!
Many people are cured of type two diabetes with gastric bypass. It occurs as quickly as the next day. There is a theory about cutting the gastric mucosa.
alpha lipoic acid, trivalent chromium, and vanadium sulfate are dirt cheap over the counter natural substances that are very effective for type2 diabetes.
this article is unclear....it almost seems like too much fat in our diets is suppressing the good enzyme...anyone else readaing it that way..
It will never happen. If diseases get cured no one makes money. There will be new “treatments” of course...
It would seem that the researcher has found a method of manually switching back to the “low fat” or “normal” gene expression state. T2 diabetes is multifactorial and the other causal factors will not be corrected by this process.
Another problem would be that the T2 diabetic would need to alter his food consumption patterns to protect the newly corrected state. Many T2 diabetics would maintain their carbohydrate heavy consumption patterns because they need the higher levels of glucose and insulin in order to achieve their desired serotonin levels.
A bariatric doc once told me that gastric bypass is the only known “cure” for Type 2 Diabetes. I believe that the hormone grehlin is the culprit in Type 2 DM.
Not sure how everyone has concluded that a low fat diet is the problem. The article says the more fat we eat, the less of the enzyme is produced. And the Type II diabetes was cured in mice by boosting production of the enzyme.
They don't say how they boosted production of enzyme. It might be that essential fatty acids in the diet boosted production, but they don't say. It's not clear whether all fats suppress production of the enzyme.
"We saw that certain enzymes were being repressed by the high-fat diet," Donald Jump, Ph.D., department of nutrition and exercise sciences, said.
More information about the study here:
http://oregonstate.edu/ua/ncs/archives/2010/jul/discovery-points-new-approach-diabetes-therapy
Very interesting!
I just did a search and found this:
Mice Essentially ‘Cured’ of Mild Diabetes With Enzyme
http://www.sciencedaily.com/releases/2010/07/100712141849.htm
where the interesting part, to be researched further, is:
“There are already drugs on the market, such as some fibrate drugs, that induce higher levels of elongase-5 to some extent.”
But caution is advised, it seems fibrate drugs lower triglycerides, but increase homocystein.
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