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To: zek157

>>how does ketosis work?

“The acetyl-CoA enters the citric acid cycle and undergoes an aldol condensation with oxaloacetate to form citrate. ... Along with the fatty acids, deaminated ketogenic amino acids can be converted into intermediates in the citric acid cycle and produce ketone bodies. Ketogenesis produces one ketone body per two acetyl-CoA.”
https://www.google.com/search?q=TCA+cycle+in+Ketosis

The key there is the oxaloacetate - which is required for the fat burning chemistry of the TCA.

“We now know that fat actually burns in the flame of oxaloacetate. Oxaloacetate can be derived from either glucose or amino acids [protein].”
https://musclegeek.wordpress.com/2012/05/01/are-carbs-required-for-fat-burning/

Natural Selection has made some ethnic groups better than others at processing protein [amino acids] into oxaloacetate:

“Inuit have been observed to have enlarged livers with an increased capacity for gluconeogenesis, and have greater capacity for excreting urea to remove ammonia, a toxic byproduct of protein breakdown.[54][63][64][65]”
https://en.wikipedia.org/wiki/Ketosis


60 posted on 12/26/2017 10:37:58 AM PST by HLPhat ("TO SECURE THESE RIGHTS" -- Government with any other purpose is not American.)
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To: HLPhat

Thanks, I didn’t think you need carbs to derive oxaloacetate


72 posted on 12/26/2017 11:35:06 AM PST by zek157
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