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Neuroscientists Create Most Detailed Map Ever of Hippocampus
Sci-News.com ^
| Oct 12, 2018
| News Staff / Source
Posted on 10/12/2018 7:49:46 AM PDT by ETL
The human hippocampus sits at the base of the brain. It stores memories, helps regulate emotions and guides navigation by spatial processing.
Its the first part of the brain impaired by Alzheimers; hippocampus degeneration also can cause epilepsy and other diseases.
Like a new atlas, weve constructed the most detailed diagram of the hippocampus to date. With a better map, we can see each region and how it functions, said Dr. Michael Bienkowski, co-lead author of the study.
A better map is a resource scientists can use to better understand the hippocampus and how its degeneration leads to diseases.
Researchers can use the new map of the hippocampus to deliver genetically targeted drugs to specific neurons with fewer side effect, said Dr. Hong-Wei Dong, co-lead author of the study.
Dr. Bienkowski, Dr. Dong and co-authors worked on a mouse brain because its organized similar to a human brain.
The work is part of the Mouse Connectome Project, an effort that collects data about neural connections in the brain, sharing it publicly with researchers in more than 100 countries.
Scientists have known the basic four-part architecture of the hippocampus for a long time, they said.
Whats different now is we can show its sub-regions and how nerve cells interact across the structure.
Its a night-and-day difference, akin to seeing transmission lines and power poles slung across a city by day compared to fully illuminated at night.
This new visualization traces neural pathways and connections in remarkable detail using fluorescent dyes as tracers that reveal cells, neuron junctions and connections to the rest of the brain.
It totally changes our understanding by combining a wiring diagram with gene expression of the mouse hippocampus, Dr. Bienkowski noted.
We see it doing different things, and this gives us a new way to understand how the whole thing works together.
(Excerpt) Read more at sci-news.com ...
TOPICS: Chit/Chat; Science
KEYWORDS: brain; hippocampus; neuroscience
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Brain mapping helps neuroscientists understand how specific areas function and how to create new drugs and targeted treatments
Image credit: Jim Stanis and Tyler Ard, USC Mark and Mary Stevens Neuroimaging and Informatics Institute
1
posted on
10/12/2018 7:49:46 AM PDT
by
ETL
To: ETL
2
posted on
10/12/2018 7:50:43 AM PDT
by
PghBaldy
(12/14 - 930am -rampage begins... 12/15 - 1030am - Obama's advance team scouts photo-op locations.)
To: ETL
I don’t see Brett Kavanaugh’s face seared into that hippocampus.
3
posted on
10/12/2018 7:50:54 AM PDT
by
Steely Tom
([Seth Rich] == [the Democrat's John Dean])
To: Steely Tom
Yes, Dr. Ford was part of the research?
Let me know when they’ve mapped out my Medulla Oblongata...
4
posted on
10/12/2018 7:52:31 AM PDT
by
nikos1121
(With Trump, we have our own Age of Pericles)
To: PghBaldy
..."Indelible in the hippocampus is the laughter...
"The same way that I'm sure that I'm talking to you right now," Ford replied. "It's just basic memory functions, and also just the level of norepinephrine and epinephrine in the brain that sort of as you know, that neurotransmitter encodes memories into the hippocampus so the trauma-related experience then is kind of locked there, whereas other details kind of drift."
5
posted on
10/12/2018 7:55:20 AM PDT
by
PghBaldy
(12/14 - 930am -rampage begins... 12/15 - 1030am - Obama's advance team scouts photo-op locations.)
To: ETL
6
posted on
10/12/2018 7:55:40 AM PDT
by
fishtank
(The denial of original sin is the root of liberalism.)
To: ETL
A hippo campus:
7
posted on
10/12/2018 7:57:42 AM PDT
by
SERKIT
("Blazing Saddles" explains it all.......)
To: SERKIT
And I thought it is a college for hippos.
8
posted on
10/12/2018 8:02:20 AM PDT
by
jps098
To: SERKIT
9
posted on
10/12/2018 8:07:06 AM PDT
by
ETL
(Obama-Hillary, REAL Russia collusion! Uranium-One Deal, Missile Defense, Iran Deal, Nukes: Click ETL)
To: jps098
10
posted on
10/12/2018 8:08:30 AM PDT
by
ETL
(Obama-Hillary, REAL Russia collusion! Uranium-One Deal, Missile Defense, Iran Deal, Nukes: Click ETL)
To: ETL
Recent Graduate
Of The Hippo Campus.
11
posted on
10/12/2018 8:08:55 AM PDT
by
left that other site
(For America to have CONFIDENCE in our future, we must have PRIDE in our HISTORY... DJT)
To: ETL
When the removed my hippocampus the voices immediately stopped.
Well, I still hear them but I immediately forget what they said - or what I had for breakfast.
What was I talking about?
To: ETL
hip-po-cam-pus /ˈhippôcamˌpus/ noun noun: hippocampus; plural noun: hippocampi 1. A post-secondary school for large, thick-skinned semiaquatic African mammals with massive jaws and large tusks. "Bertha is sending Junior to the hippocampus." 2. Allegedly, a part of Dr. Christine Blasey Ford's brain known for inconsistent retention of detail and prone to selective, but extensive data loss. "It was indelibly etched into my hippocampus, but I can't remember why."
13
posted on
10/12/2018 8:11:34 AM PDT
by
ManHunter
(You can run, but you'll only die tired... Army snipers: Reach out and touch someone)
To: ETL
14
posted on
10/12/2018 8:18:19 AM PDT
by
mjp
((pro-{God, reality, reason, egoism, individualism, natural rights, limited government, capitalism}))
To: jps098
That was funny! Still laughing!!
15
posted on
10/12/2018 8:19:22 AM PDT
by
FES0844
To: ETL
Christine Ford's hippocampus.
16
posted on
10/12/2018 8:23:09 AM PDT
by
UCANSEE2
(Lost my tagline on Flight MH370. Sorry for the inconvenience.)
To: ETL
Dr. Hong-Wei Dong
Long Ducs brother?
To: ETL
Useful map if you want to know where they are camping.
18
posted on
10/12/2018 8:35:37 AM PDT
by
MNDude
(WWG1WGA)
To: ETL
Did they find indellible laughter?
To: PghBaldy
She was right! Indelible is the laughter!
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