Posted on 12/26/2019 8:57:41 PM PST by ConservativeMind
A ketone-supplemented diet may protect neurons from death during the progression of Alzheimer's disease, according to research in mice recently published in JNeurosci.
Early in the development of Alzheimer's disease, the brain becomes over excited, potentially through the loss of inhibitory, or GABAergic, interneurons that keep other neurons from signaling too much. Because interneurons require more energy compared to other neurons, they may be more susceptible to dying when they encounter the Alzheimer's disease protein amyloid beta. Amyloid beta has been shown to damage mitochondria -- the metabolic engine for cells -- by interfering with SIRT3, a protein that preserves mitochondrial functions and protects neurons.
Cheng et al. genetically reduced levels of SIRT3 in mouse models of Alzheimer's disease. Mice with low levels of SIRT3 experienced a much higher mortality rate, more violent seizures, and increased interneuron death compared to the mice from the standard Alzheimer's disease model and control mice. However, the mice with reduced levels of SIRT3 experienced fewer seizures and were less likely to die when they ate a diet rich in ketones, a specific type of fatty acid. The diet also increased levels of SIRT3 in the mice.
Increasing SIRT3 levels via ketone consumption may be a way to protect interneurons and delay the progression of Alzheimer's disease.
(Excerpt) Read more at sciencedaily.com ...
Just eat a Keto diet, high-fat, low-carb.
How do you eat ketones? I thought they were something your body made.
While I do see a lot of evidence that adopting a ketogenic diet is an effective way to drop body fat, I’m not sold on ingesting ketones as a way to mimic the effects. To me it would be like someone saying “people who work out a lot are healthy and they sweat a lot, so here, drink some of this sweat, it’s going to do practically the same thing as a workout.”
Your body produces Ketones, you don’t need to ingest them.
Ketones are produced when fat is metabolized... Maybe folks aren’t eating enough fat?
Typically, this is done by your body in very low carb diet.
https://www.livestrong.com/article/517437-foods-that-have-ketones/
Ping to you.
Hmmm. My wife doesn't have a gall bladder. I suspect she metabolized very little fat. How will she produce enough ketones?
MCT oil. Three tablespoons a day that your liver can turn into enough ketones to make up for a 10% loss of brain function.
https://www.youtube.com/watch?v=XxGiQ7YrUYE
Start slow, as it will give you diarrhea if you aren’t used to it.
Costco has it, two 20oz bottles for about $22. Or Amazon, if you can wait a day or two. :)
Fast forward the video to about 19m40s.
A Tablespoon of Coconut oil in your morning coffee does the trick...
https://ketogenicwoman.com/coconut-oil-on-the-ketogenic-diet/
I read the title as “eat more KITTENs”...
similar problem with those CPAP commercials.
Dementia is not funny;)
Do you know if the Costco oil contains just the C8 and C10 mct chains, or does it contain C12 as well, because the C12 (Lauric acid) is inferior. I paid about $24 for 32 Oz. for Left Coast mct oil on amazon.
Sure. And in 6 months there will be a “study” that says the opposite.
The article says essentially nothing, since it qualifies everything with “may.”
“Just eat a Keto diet, high-fat, low-carb.”
I’m with you, if I want Ketones, I’ll just go low-carb and my body will produce just the Ketones that I need (including Acetone).
No need to go to Home Depot and buy Acetone, as it tastes lousy and is lethal to drink.
Check out https://keto-mojo.com. Lots of great info.
Problem is kittens don’t have much fat...
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