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Azithromycin plus chloroquine:combination therapy for protection against malaria and sexually transmitted infections in pregnancy
Expert Opin Drug Metab Toxicol ^ | September 2011 | R Matthew Chico & Daniel Chandramohan

Posted on 04/24/2020 8:46:58 AM PDT by ScaniaBoy

Introduction:

The first-line therapy for the intermittent preventive treatment of malaria in pregnancy (IPTp) is sulphadoxine-pyrimethamine (SP). There is an urgent need to identify safe, well-tolerated and efficacious alternatives to SP due to widespread Plasmodium falciparum resistance. Combination therapy using azithromycin and chloroquine is one possibility that has demonstrated adequate parasitological response > 95% in clinical trials of non-pregnant adults in sub-Saharan Africa and where IPTp is a government policy in 33 countries.

Areas covered:

Key safety, tolerability and efficacy data are presented for azithromycin and chloroquine, alone and/or in combination, when used to prevent and/or treat P. falciparum, P. vivax, and several curable sexually transmitted and reproductive tract infections (STI/RTI). Pharmacokinetic evidence from pregnant women is also summarized for both compounds.

......

(Excerpt) Read more at ncbi.nlm.nih.gov ...


TOPICS: Health/Medicine; Miscellaneous; Science; Society
KEYWORDS: azithromycin; chloroquine; sideeffects; toxicity
I found this article linked at the Mediterranne-Infection.com site under the title
Toxicité Chloroquine-Azithromycin une crise de nerf française : étude sur 755 femmes enceintes

[Toxicity of chlorquine-azithromycin a French nervous breakdown: study on 755 pregnant women.]

In short, several years before the present pandemic and long before President Trump ever uttered the word chloroquine the toxicity of the combination of Azithromycin and Chloroquine had been tested in several countries in doses higher than suggested for CoV-19 in pregnant women.

And for those who don't have time to read the whole article, here is the first sentences of the conclusion:

Azithromycin-chloroquine is a potential alternative to SP, having shown efficacy against P. falciparum among non-pregnant adults in sub-Saharan Africa, Colombia and India, even in the presence of parasite populations saturated with chloroquine-resistance markers. The combination may be safely administered any time in pregnancy and offers benefits of clearing several STI/RTI.

1 posted on 04/24/2020 8:46:58 AM PDT by ScaniaBoy
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To: ScaniaBoy

Yes, and millions are dropping dead! Scary!


2 posted on 04/24/2020 9:16:11 AM PDT by alstewartfan (The shore was washed away.They say you hear church bells still as they toll beneath the waves. Al S)
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To: wastoute

btt


3 posted on 04/24/2020 9:36:42 AM PDT by GailA (I'm a Trump Girl)
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To: ScaniaBoy

Fauci didn’t like it because he is FOR sexually transmitted disease.


4 posted on 04/24/2020 9:37:48 AM PDT by Fido969 (In!)
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To: ScaniaBoy

From the article: “Six times the therapeutic dose of 600 mg chloroquine can produce hypotension and cardiac failure [58]. Nevertheless, chloroquine is generally well tolerated in treatment doses”

Chugging a liter of everclear may also kill you.


5 posted on 04/24/2020 10:09:03 AM PDT by calico_thompson (Vanity sarcasm)
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To: calico_thompson

At age 19,When I did it with a bunch of sorority girls, I thought I’d died and gone to heaven.


6 posted on 04/24/2020 10:32:27 AM PDT by Waverunner (I'd like to welcome our new overlords, say hello to my little friend)
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