Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

One in twenty achieve remission from type 2 diabetes
Medical XPress / Public Library of Science / PLoS Med ^ | Nov. 2, 2021 | Captieux M, Fleetwood K, Kennon B, Sattar N, Lindsay R, Guthrie B, et al.

Posted on 11/03/2021 9:46:17 PM PDT by ConservativeMind

Around one in twenty people in Scotland diagnosed with type 2 diabetes achieve remission from the disease. This suggests people are achieving remission outside of research trials and without bariatric surgery. Recognising individuals in remission, following their progress, and better understanding the factors involved in remission could lead to improved initiatives to help others.

There were an estimated 463 million people with diabetes in the world in 2019, of whom 90-95% have type 2 diabetes, and these numbers are rising due to ageing populations, growing obesity and sedentary lifestyles. Some people with type 2 diabetes have achieved remission after bariatric surgery, or after taking part in a research trial of a very low-calorie diet, but it is unknown how many people in the general population are in remission. Using a national register of people with type 2 diabetes in Scotland, Mireille Captieux and colleagues estimated how many people were in remission in 2019 and described the characteristics of those in remission and not in remission.

Of 162,316 patients aged over 30 years who were eligible for the analysis, 7,710—around 5%—were in remission in 2019. Individuals in remission tend to have not previously taken glucose lowering medication; have lost weight since their diagnosis; be older; have lower blood sugar levels at diagnosis; or have had bariatric surgery. Understanding how many individuals are in remission as well as their characteristics creates a baseline against which to evaluate future initiatives and studies. It could also help clinicians identify patients with whom to discuss remission and weight management options.

"We have been able to show, for the first time, that 1 in 20 people in Scotland with type 2 diabetes achieve remission. This is higher than expected and indicates a need for updated guidelines to support clinicians in recognising and supporting these individuals."

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: diabetes; type2
Navigation: use the links below to view more comments.
first 1-2021-40 next last
It is happening with increasing frequency.

Intermittent fasting is best, followed by keto/low carb.

1 posted on 11/03/2021 9:46:17 PM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: ConservativeMind; All

Honestly surprised its not higher

Its not hard to fast when all you eat is Scottish cuisine


2 posted on 11/03/2021 9:48:29 PM PDT by Secret Agent Man (Gone Galt; not averse to Going Bronson.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

bfl


3 posted on 11/03/2021 9:51:54 PM PDT by freedumb2003 (The democrats have just replaced KKK with CRT. /Kevin McCarty 7/6/21)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

On what plan? It seems like the standard treatment makes it worse - and the science backs that up?


4 posted on 11/03/2021 9:52:24 PM PDT by nickcarraway
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Is there any scientific evidence that diabetes is never cured, but only in remission?


5 posted on 11/03/2021 9:53:23 PM PDT by nickcarraway
[ Post Reply | Private Reply | To 1 | View Replies]

To: nickcarraway

Yes. Your pancreas would need to be replaced to be cured. The insulin receptors are damaged or dead. When they reach a critical level for your weight, you develop type 2 diabetes. They do not re-grow. Therefore the only cure would be to replace your pancreas. Remission can be achieved through diet (keto is best), intermittent fasting, bariatric surgery, weight loss (so your remaining receptors can handle the load).


6 posted on 11/03/2021 10:00:21 PM PDT by Whatever Works
[ Post Reply | Private Reply | To 5 | View Replies]

To: nickcarraway

“There’s no cure for type 2 diabetes, but losing weight, eating well and exercising can help you manage the disease. If diet and exercise aren’t enough to manage your blood sugar, you may also need diabetes medications or insulin therapy.”

https://www.mayoclinic.org/diseases-conditions/type-2-diabetes/symptoms-causes/syc-20351193


7 posted on 11/03/2021 10:02:15 PM PDT by Pelham (Q is short for quack)
[ Post Reply | Private Reply | To 5 | View Replies]

To: Whatever Works

I don’t think they have scientific evidence of what you say. There may indeed be people with damaged receptors, but I don’t think science has fully understood or proved that.


8 posted on 11/03/2021 10:03:52 PM PDT by nickcarraway
[ Post Reply | Private Reply | To 6 | View Replies]

To: ConservativeMind

Um, well...perhaps, if it’s not permanent (the ‘diet’).

True story: Gave a guy the draft of my book and he carried around JUST 2 pages in his pocket for a year. I found out about that fact after the year when he told me he’d just come from the doctor who’d taken him off of all his meds (he was type-2, among other ailments).

Today, I was in an office doing my job overhearing women in their cubicles talking to each other, arguing over calories, gluten dairy and discussing gluten-free replacements for real food vs. quality/taste. It was hard to listen to and stay silent.

My point is that much of what I read on ‘health’ is akin to turning up the radio to mask a squeak/noise or, better, driving down one street and not the other one because the rough road on the other causes abnormal noises.

Or worse, driving with the radio up so long that the wheels fall off.

It’s not complicated, but I’ve found that fewer than 1-in-1000 can wrap their heads around that on health matters (and fewer achieve goals without the wheels falling off for other reasons, usually what they imparted to influence health changes).


9 posted on 11/03/2021 10:04:10 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Pelham
I know what the standard view is. Until September of this year, the American Diabetes Association, and other organizations said that remission was impossible. Now they admit it is possible, though other groups/doctors still don't.

My only point is we don't really have strong science to back this up, or to fully understand. A lot of what is considered standard medical science is just based on what is widely believed, not solid science.

10 posted on 11/03/2021 10:08:20 PM PDT by nickcarraway
[ Post Reply | Private Reply | To 7 | View Replies]

To: nickcarraway

I recently did a lot of reading on this topic.

From what I understand, yes, once the body reaches point of type 2 it never goes back to “normal.” The cells in liver and pancreous that deal with blood sugar are destroyed over a long time of being abused. Once destroyed never regenerate. Blood sugar can be controlled with diet and excercise but those particular cells needed to deal with sugar never come back.

Remission is acheived with dedicated diet modification and excercise. But, much easier for a person to not change his life and take a pill thus the numbers are bad and getting worse every year.

Moral of the story: take care of yourself before it is too late.


11 posted on 11/03/2021 10:11:33 PM PDT by JParris
[ Post Reply | Private Reply | To 5 | View Replies]

To: Whatever Works; nickcarraway

There is some evidence stem cells migrate to the pancreas to replace lost beta cells. It comes from an intermittent fasting approach from a couple years back.

I’m heading to bed now, but yes, it is possible to regenerate those cells.


12 posted on 11/03/2021 10:12:53 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 6 | View Replies]

To: JParris

I will qualify this:

I did read of a study, only the summary not the study, performed by UK NIH as I recall. They did report cases of remission if the condition was detected early enough and an extreme diet of 500 - 700 calories per day consumed until reduction of 15% - 20% of body weight was achieved.

But the key was early detection and fast massive weight loss to achieve remission.


13 posted on 11/03/2021 10:23:27 PM PDT by JParris
[ Post Reply | Private Reply | To 11 | View Replies]

To: nickcarraway

That seems odd. The idea that Type 2 can go into remission via weight loss and a low carb diet isn’t new. It goes back at least to the 1930s. It was the sole option prior to the introduction of insulin.


14 posted on 11/03/2021 10:26:37 PM PDT by Pelham (Q is short for quack)
[ Post Reply | Private Reply | To 10 | View Replies]

To: JParris
Dr. Jason Fung did a small study (Only because it's hard to get funding for something that won't make a company money) and reversed men who had long-term diabetes. It was based on results at his clinic where he gets those results frequently.

There is a very good study at Indiana University where they deliberately picked people with long term diabetes. (I believe the average was eight years) That study had amazing results, with maybe 65% going off medication completely, including people who had it for decades.

15 posted on 11/03/2021 10:29:55 PM PDT by nickcarraway
[ Post Reply | Private Reply | To 13 | View Replies]

To: Pelham

What you say is true, but once insulin was discovered that idea went away once insulin was discovered. For 50 years or more, patients have been told it’s a chronic condition that gets worse. The American Diabetes Association didn’t acknowledge remission until September 2021. [I should say, this all refers to Type 2 diabetes. Type 1/juvenile is completely different]


16 posted on 11/03/2021 10:33:52 PM PDT by nickcarraway
[ Post Reply | Private Reply | To 14 | View Replies]

To: nickcarraway

What are the basic principles for Dr. Fung’s treatment / diet?


17 posted on 11/03/2021 10:43:07 PM PDT by ConjunctionJunction
[ Post Reply | Private Reply | To 15 | View Replies]

To: nickcarraway

I don’t doubt that at all.

But what is definition of “reversed?” If “reversed” is elimination of medication or insulin then absolutely can be and is achieved. However, in those the condition is “reversed” they can not go back to consuming a dozen krispy kreme and washing it down with a liter of coke as they did at 20 yo.

Bottom line is as we age we must account for degradation of our bodies with improved diet, exercise and weight loss. Or we can maintain unhealthy habits and compensate with commercially produced chemicals. The vast majority will choose chemicals over eliminating krispy kreme and coke.


18 posted on 11/03/2021 10:43:22 PM PDT by JParris
[ Post Reply | Private Reply | To 15 | View Replies]

To: ConjunctionJunction

Fasting (of various lengths and protocols) and low carbs diets. [That is a very brief nutshell]


19 posted on 11/03/2021 10:46:51 PM PDT by nickcarraway
[ Post Reply | Private Reply | To 17 | View Replies]

To: JParris
However, in those the condition is “reversed” they can not go back to consuming a dozen krispy kreme and washing it down with a liter of coke as they did at 20 yo.

The same could be said of someone who didn't have diabetes in the first place.

If we had someone who was morbidly obese, and they lost weight, and were at their "ideal" weight, would we say, "They aren't at a normal weight, their diabetes is just in remission. They could gain all that weight back."

20 posted on 11/03/2021 10:49:05 PM PDT by nickcarraway
[ Post Reply | Private Reply | To 18 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-40 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson