Posted on 12/12/2021 8:32:05 PM PST by SeekAndFind
This evidence showed a 7% reduction in COVID-19 infection rate with use of ivermectin: COVID-19 infection rate ratio (Risk ratio (RR) of 0.93; 95% confidence interval (CI), 0.89 – 0.98; p = 0.003).
A total of 62 deaths (1.4% mortality rate) occurred among users and 79 deaths (2.6% mortality rate) among non-users, showing a 48% reduction in mortality rate (RR, 0,52; 95%CI, 0.37 – 0.72; p = 0.0001).
Risk of dying from COVID-19 among ivermectin users was 45% lower than non-users (RR, 0.55; 95%CI, 0.40 – 0.77; p = 0.0004).
Prophylactic use of ivermectin showed significantly reduced COVID-19 infection rate, mortality rate and chance of dying from COVID-19 on a calculated population-level analysis, which controlled for all relevant confounding variables.
Ping for your interest...
Preprint available here:
Results robust to all reasonable confounders in propensity-score matched analysis thanks to a rich data set.
The results can be considered quasi-randomised.
The Brazilian city of Itajai has offered Ivermectin as prophylaxis (0.2mg/day/kg for 2 days every 2 weeks) to its 220,000 inhabitants and meticulously tracked the results.
60% (with higher risk) took IVM over 7 months.
The Covid hospitalization and mortality rates were HALVED.
Thank you. This should make for great discussion. At least 70% of the people I know are convinced of natural immunity’s integrity.
Thanks for that article. Very useful reference.
This article from Zero Hedge actually refers to this research:
TITLE: Hospitalizations, Mortality Cut In Half After Brazilian City Offered Ivermectin To Everyone Pre-Vaccine
[EXCERPT]
Study limitations:
The authors note, “Being a retrospective observational analysis, it is uncertain whether results would be reproducible in a randomized, placebo-controlled, double-blind clinical trial, but likely, since groups of ivermectin users and non-users had similar demographic characteristics, and rates were adjusted for the relevant confounding variables.”
We’re sure the ‘fact checkers’ are already hard at work trying to debunk the pre-print, however they may also want to take a look at ivmmeta.com - a real-time meta analysis of 70 studies which found that Ivermectin works as a prophylaxis 83% of the time. In peer-reviewed studies, it was found effective 70% of the time as an early treatment, and just 39% of the time as a late treatment.
As we noted during the whole ‘horse paste’ controversy
I’m glad you posted this.
I use ResearchGate and Academia.edu all the time.
Invaluable resources.
(source, May 12th) Separately, there have been several studies funded by the Indian government, primarily conducted through their largest govt. public medical university (AIIMS).
Conclusion: Two-dose ivermectin prophylaxis at a dose of 300 μg/kg with a gap of 72 hours was associated with a 73% reduction of SARS-CoV-2 infection among healthcare workers for the following month.
Conclusion: There was no difference in the primary outcome i.e. negative RT-PCR status on day 6 of admission with the use of ivermectin. However, a significantly higher proportion of patients were discharged alive from the hospital when they received ivermectin.
Discussion: In the present study, patients with mild or moderate COVID-19 infection treated with ivermectin in combination with doxycycline generally recovered 2 days earlier than those treated with placebo. The proportion of patients responding within 7 days of treatment was significantly higher in the treatment group than in the placebo group. The proportions of patients who remained symptomatic after 12 days of illness and who experienced disease progression were significantly lower in the treatment group than in the placebo group.
For the 24 states with early IVM treatment (and Lima), excess deaths dropped 59% (25%) at +30 days and 75% (25%) at +45 days after day of peak deaths. Case fatalities likewise dropped sharply in all states but Lima
Findings: Patients in the ivermectin group recovered earlier from hyposmia/anosmia (76 vs 158 patient-days; p < 0.001).
Conclusion: According to our study, the Ivermectin-Doxycycline combination therapy has better symptomatic relief, shortened recovery duration, fewer adverse effects, and superior patient compliance compared to the Hydroxychloroquine-Azithromycin combination. Based on this study's outcomes, the Ivermectin-Doxycycline combination is a superior choice for treating patients with mild to moderate COVID-19 disease.
Discussion: A 5-day course of ivermectin resulted in an earlier clearance of the virus compared to placebo (p = 0.005), thus indicating that early intervention with this agent may limit viral replication within the host. In the 5-day ivermectin group, there was a significant drop in CRP and LDH by day 7, which are indicators of disease severity.
Why does Ivermectin, a 'horse dewormer' work? For starters, an in-vitro study shows that it's a protease inhibitor. Interestingly, Pfizer's 2x/day Covid-19 prophylactic they're trialing right now is also a protease inhibitor.
Perhaps the most damning evidence in favor of Ivermectin is the medical establishment's position that it's essentially snake oil, despite the fact that it's had a glowing safety profile for decades, until now.
Based on the stats and the cost. IV “For humans” looks like it should be standard care. No hospitalization required. A pill
Can’t get any. Cannot get it approved from the pharmacy. Where can I get the pills?
What does the study have to do with “natural immunity”?
Indiamart if no where else.
FLCCC
it took awhile
Do you have an Rx?
PING
Try honeybeehealth.com
:-)
Don’t need to....our pharmacies fill our Rx’s.
Was just trying to help the poster who was asking.
Risk of dying from COVID-19 among ivermectin users was 45% lower than non-users (RR, 0.55; 95%CI, 0.40 – 0.77; p = 0.0004).
Conclusion:
Prophylactic use of ivermectin showed significantly reduced COVID-19 infection rate, mortality rate and chance of dying from COVID-19 on a calculated population-level analysis, which controlled for all relevant confounding variables.
Versus the hazardous, adverse effects of the $hots.
I’ll go with the Ivm and natural immunity.
just found this on patriots.win
Dr. Andrew Hill, PhD and Dr. Tess Lawrie
[Discussing Ivermectin]
Lawrie: I really, really wish, and you’ve explained quite clearly to me, in both what you’ve been saying and in your body language that you’re not entirely comfortable with your conclusions, and that you’re in a tricky position because of whatever influence people are having on you, and including the people who have paid you and who have basically written that conclusion for you.
Hill: You’ve just got to understand I’m in a difficult position. I’m trying to steer a middle ground and it’s extremely hard.
Lawrie: Yeah. Middle ground. The middle ground is not a middle ground …You’ve taken a position right to the other extreme calling for further trials that are going to kill people. So this will come out, and you will be culpable.
Lawrie: Lots of people are in sensitive positions; they’re in hospital, in ICUs dying, and they need this medicine.
Hill: Well …
Lawrie: This is what I don’t get, you know, because you’re not a clinician. You’re not seeing people dying every day. And this medicine prevents deaths by 80 percent. So 80 percent of those people who are dying today don’t need to die because there’s ivermectin.
Hill: There are a lot, as I said, there are a lot of different opinions about this. As I say, some people simply …
Lawrie: We are looking at the data; it doesn’t matter what other people say. We are the ones who are tasked with looking at the data and reassuring everybody that this cheap and effective treatment will save lives. It’s clear. You don’t have to say, well, so-and-so says this, and so-and-so says that. It’s absolutely crystal clear. We can save lives today. If we can get the government to buy ivermectin.
Hill: Well, I don’t think it’s as simple as that, because you’ve got trials …
Lawrie: It is as simple as that. We don’t have to wait for studies … we have enough evidence now that shows that ivermectin saves lives, it prevents hospitalization. It saves the clinical staff going to work every day and being exposed. And frankly, I’m shocked at how you are not taking responsibility for that decision.
And you still haven’t told me who is [influencing you]? Who is giving you that opinion? Because you keep saying you’re in a sensitive position. I appreciate you are in a sensitive position, if you’re being paid for something and you’re being told [to support] a certain narrative … that is a sensitive position.
So, then you kind of have to decide, well, do I take this payment? Because in actual fact, [you] can see [your false] conclusions are going to harm people. So maybe you need to say, I’m not going to be paid for this.
I can see the evidence, and I will join the Cochrane team as a volunteer, like everybody on the Cochrane team is a volunteer. Nobody’s being paid for this work.
Hill: I think fundamentally, we’re reaching the [same] conclusion about the survival benefit. We’re both finding a significant effect on survival.
Lawrie: No, I’m grading my evidence. I’m saying I’m sure of this evidence. I’m saying I’m absolutely sure it prevents deaths. There is nothing as effective as this treatment. What is your reluctance? Whose conclusion is that?
[Hill complains again that outsiders are influencing him.]
Lawrie: You keep referring to other people. It’s like you don’t trust yourself. If you were to trust yourself, you would know that you have made an error and you need to correct it because you know, in your heart, that this treatment prevents death.
Hill: Well, I know, I know for a fact that the data right now is not going to get the drug approved.
Lawrie: But, Andy — know this will come out. It will come out that there were all these barriers to the truth being told to the public and to the evidence being presented. So please, this is your opportunity just to acknowledge [the truth] in your review, change your conclusions, and come on board with this Cochrane Review, which will be definitive. It will be the review that shows the evidence and gives the proof. This was the consensus on Wednesday night’s meeting with 20 experts.
[Hill protests that the U.S. National Institutes of Health will not agree to recommend ivermectin.]
Lawrie: Yeah, because the NIH is owned by the vaccine lobby.
Hill: That’s not something I know about.
Lawrie: Well, all I’m saying is this smacks of corruption and you are being played.
Hill: I don’t think so.
Lawrie: Well then, you have no excuse because your work in that review is flawed. It’s rushed. It is not properly put together.
Lawrie points out that Hill’s study ignores a host of clinical outcomes that affect patients. She scolds Hill for ignoring the beneficial effects of ivermectin as prophylaxis, its effect on speed to testing negative for the virus, on the need for mechanical ventilation, on reduced admissions to intensive care, and other outcomes that are clinically meaningful.
This is bad research … bad research. So, at this point, I don’t know … you seem like a nice guy, but I am really, really worried about you.
Hill: Okay. Yeah. I mean, it’s, it’s a difficult situation.
Lawrie: No, you might be in a difficult situation. I’m not, because I have no paymaster. I can tell the truth. How can you deliberately try and mess it up … you know?
Hill: It’s not messing it up. It’s saying that we need, we need a short time to look at some more studies.
Lawrie: So, how long are you going to let people carry on dying unnecessarily – up to you? What is, what is the timeline that you’ve allowed for this, then?
Hill: Well, I think . . . I think that it goes to WHO [World Health Organization]and the NIH [National Institutes of Health]and the FDA [U.S. Food and Drug Administration] and the EMA [European Medicines Agency]. And they’ve got to decide when they think enough’s enough.
Lawrie: How do they decide? Because there’s nobody giving them good evidence synthesis, because yours is certainly not good.
Hill: Well, when yours comes out, which will be in the very near future … at the same time, there’ll be other trials producing results, which will nail it with a bit of luck. And we’ll be there.
Lawrie: It’s already nailed.
Hill: No, that’s, that’s not the view of the WHO and the FDA.
Lawrie: You’d rather risk loads of people’s lives. Do you know if you and I stood together on this, we could present a united front and we could get this thing. We could make it happen. We could save lives; we could prevent [British National Health Service doctors and nurses] people from getting infected. We could prevent the elderly from dying.
These are studies conducted around the world in several different countries. And they’re all saying the same thing. Plus there’s all sorts of other evidence to show that it works. Randomized controlled trials do not need to be the be-all and end-all. But [even] based on the randomized controlled trials, it is clear that ivermectin works. It prevents deaths and it prevents harms and it improves outcomes for people …
I can see we’re getting nowhere because you have an agenda, whether you like it or not, whether you admit to it or not, you have an agenda. And the agenda is to kick this down the road as far as you can. So … we are trying to save lives. That’s what we do.
I’m a doctor and I’m going to save as many lives as I can. And I’m going to do that through getting the message [out] on ivermectin. Okay. Unfortunately, your work is going to impair that, and you seem to be able to bear the burden of many, many deaths, which I cannot do.
Lawrie: Would you tell me? I would like to know who pays you as a consultant through WHO?
Hill: It’s Unitaid.
Lawrie: All right. So who helped to … Whose conclusions are those on the review that you’ve done? Who is not listed as an author? Who’s actually contributed?
Hill: Well, I mean, I don’t really want to get into, I mean, it … Unitaid …
Lawrie: I think that . . . it needs to be clear. I would like to know who, who are these other voices that are in your paper that are not acknowledged? Does Unitaid have a say? Do they influence what you write?
Hill: Unitaid has a say in the conclusions of the paper. Yeah.
Lawrie: Okay. So, who is it in Unitaid, then? Who is giving you opinions on your evidence?
Hill: Well, it’s just the people there. I don’t …
Lawrie: So they have a say in your conclusions.
Hill: Yeah.
Lawrie: Could you please give me a name of someone in Unitaid I could speak to, so that I can share my evidence and hope to try and persuade them to understand it?
Hill: Oh, I’ll have a think about who to, to offer you with a name … but I mean, this is very difficult because I’m, you know, I’ve, I’ve got this role where I’m supposed to produce this paper and we’re in a very difficult, delicate balance …
Lawrie: Who are these people? Who are these people saying this?
Hill: Yeah … it’s a very strong lobby …
Lawrie: Okay. Look, I think I can see kind of a dead end, because you seem to have a whole lot of excuses, but, um, you know, that to, to justify bad research practice. So I’m really, really sorry about this, Andy.
I really, really wish, and you’ve explained quite clearly to me, in both what you’ve been saying and in your body language that you’re not entirely comfortable with your conclusions, and that you’re in a tricky position because of whatever influence people are having on you, and including the people who have paid you and who have basically written that conclusion for you.
Hill: You’ve just got to understand I’m in a difficult position. I’m trying to steer a middle ground and it’s extremely hard.
Lawrie: Yeah. ‘Middle ground.’ The ‘middle ground’ is not a ‘middle ground’ … You’ve taken a position right to the other extreme calling for further trials that are going to kill people. So this will come out, and you will be culpable.
And I can’t understand why you don’t see that, because the evidence is there and you are not just denying it, but your work’s actually actively obfuscating the truth. And this will come out. So I’m really sorry … As I say, you seem like a nice guy, but I think you’ve just kind of been misled somehow.
[Hill promises he will do everything in his power to get ivermectin approved if she will give him six weeks.]
Hill: Well, what I hope is that this, this stalemate that we’re in doesn’t last very long. It lasts a matter of weeks. And I guarantee I will push for this to last for as short amount of time as possible.
Lawrie: So, how long do you think the stalemate will go on for? How long do you think you will be paid to [make] the stalemate go on?
Hill: From my side. Okay … I think end of February, we will be there, six weeks.’
Lawrie: How many people die every day?
Hill: Oh, sure. I mean, you know, 15,000 people a day.
Lawrie: Fifteen thousand people a day times six weeks … because at this rate, all other countries are getting ivermectin except the UK and the USA, because the UK and the USA and Europe are owned by the vaccine lobby.
Hill: My goal is to get the drug approved and to do everything I can to get it approved so that it reaches the maximum …
Lawrie: You’re not doing everything you can, because everything you can would involve saying to those people who are paying you, “I can see this prevents deaths. So I’m not going to support this conclusion any more, and I’m going to tell the truth.”
Hill: What, I’ve got to do my responsibilities to get as much support as I can to get this drug approved as quickly as possible.
Lawrie: Well, you’re not going to get it approved the way you’ve written that conclusion. You’ve actually shot yourself in the foot, and you’ve shot us all in the foot. All of … everybody trying to do something good. You have actually completely destroyed it.
Hill: Okay. Well, that’s where we’ll, I guess we’ll have to agree to differ.
Lawrie: Yeah. Well, I don’t know how you sleep at night, honestly.
Primary source: Robert Kennedy (book) Endorsed by: Dr. Pierre Kory (Tweet) Repeated by: Neville Hodgkinson, former medical and science correspondent at the Sunday Times Pending: Statements by Hill & Lawrie
HERESY!!! Burn the unbelievers. Ivermectin is the most dangerous drug since HCQ.
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