[E. Pluribus Unum]

Crazy is crazy. Who knew?

[Gay State Conservative]

A few years ago I had the good fortune to meet a brain researcher from the Karolinska Institute in Stockholm. We were in the same party of a safari tour company at Kruger National Park in South Africa. You can't go out at night (too dangerous) so we all sat around the fire at night talking.Martin did most of the talking because the other three in our party were also in medicine and found him fascinating (as did I).

At one point he said "scientists know more about the surface of the moon than we do about the human brain".

[heartwood]

There are other genes known to link major depressive disorder, bipolar, obsessive compulsive, schizophrenia, autism, and ADHD.

If any of these have popped up in your family, you’d be wise to take care who you have children with.

Don’t double down.

[willk]

So all these illnesses are treatable to some degree with modern pharmaceuticals. What about Chronic Schizophrenia which does not seem to respond to any treatments? Maybe an illness not linked to all the others?

[nagant]

Bipolar manic depression has always been recognized as a symptom of schizophrenia.

I believe there to be a few causes:

1. Autoimmune response to ingested and mimicked opioids introduced through inflamed vagus nerves

2. Adolescent unchecked clearing of unused brain synapses

3. Autoimmune response to mitochondrial degradation and presentation on nerve cell walls

4. Prion disease.

5. ?

[aimhigh]

In addition to AKAP11, the most common genetic deletion is called 22Q11. 30% of 22Q11 patients become schizophrenic by age 22.