Posted on 01/22/2023 6:24:51 PM PST by ConservativeMind
Chromatin forms the structural basis of chromosomes in the cellular nuclei. When cells die, they release cell-free chromatin particles, or cfChPs, into the circulatory system.
Emerging evidence indicates that cfChPs play an essential role in aging, sepsis, cancer development, and chemotherapy-related toxicity.
Prof. Mittra explains, "Chemo-toxicity is not primarily caused by chemotherapeutic drugs, but rather by cfChPs that are released from the first cells that die after chemotherapy."
Recently, a team have demonstrated the therapeutic benefits of a pro-oxidant mixture of resveratrol and copper, R-Cu, in patients undergoing chemotherapy for advanced gastric cancer. Combining R with Cu (R-Cu) leads to the generation of free oxygen radicals which can inactivate the offending cfChPs.
Prior to this, two studies from Prof. Mittra's group used mouse models to demonstrate the benefits of R-Cu administration in the prevention of aging and sepsis. The first of these indicated that cfChPs that are released from the billions of cells that die in the body every day and damage healthy cells is the underlying cause of aging, and prolonged oral administration of R-Cu leads to the downregulation of multiple biological parameters of aging including neurodegeneration, which is associated with Alzheimer's disease.
The other study showed how cfChPs trigger sepsis after bacterial infection in mice; administering R-Cu prevented this pathological process, including the prevention of fatality.
The research group also conducted human studies. One of their previous works suggested that cfChPs released from dying cancer cells enter surrounding surviving cancer cells and trigger DNA damage and inflammation and further contribute to their aggressive behavior—effects that could be mitigated by R-Cu administration. Another study reports reduced grade 3/4 mucositis and reduced levels of inflammatory proteins (or cytokines) in the serum and saliva of R-Cu-treated patients receiving bone marrow transplants with high-dose melphalan—a chemotherapeutic used to treat plasma cell cancers.
(Excerpt) Read more at medicalxpress.com ...
A quick search on the Internet and Amazon did not come up with any hits. Do you know where/how to get it?
Just curious.
Maybe they should try pterostilbene. It’s similar to resveratrol but has much better bioavailability.
You can get it at the health food store and from blueberries.
Your the compound is simply resveratrol and copper, bit the ratio and amounts are in the attached papers.
One would want a doctor to dose this with conditions like cancer, as all sorts of antioxidants can normally interfere with chemo. Some don’t, but using an antioxidant as an oxidant is new territory, but it is available today.
We don’t normally want oxidants.
Some antioxidants become oxidants at higher dosages like vitamin C or grape seed extract.
https://pubmed.ncbi.nlm.nih.gov/14734830/
Every time a break through is shown, it’s the last we ever hear about it. I remember Israel had a huge break through for cancer treatment. It has been buried never to be seen again
Cancer is an “industry” that seeks treatments, but not a cure.
“A quick search on the Internet and Amazon did not come up with any hits. Do you know where/how to get it?”
Amazon.com
I’ve been taking resveratrol and a men’s multi-vitamin with minerals for at least 25 years. When I tell people that I am 60, or ask them to guess my age, they always guess mid to late 40s. I have NO wrinkles on my neck or face and if it weren’t for my grey hair I absolutely believe that I have a more myouthful appearance than my 60 years should show.
Yeah I’m 70. but I’m told I look 60. I even took a biological age test which showed biologically I’m only 60. But then I’ve always looked 10 years younger than I am.
That said, I do try to live as healthy as I can.
But I do wonder how much of it is genetic and how much of the good health is life style.
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