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Alcohol drinking cut in half with diabetes medication (Semaglutide (Ozempic))
Medical Xpress / University of Gothenburg / eBioMedicine ^ | June 8, 2023 | Cajsa Aranäs et al

Posted on 06/11/2023 1:10:40 PM PDT by ConservativeMind

The medication semaglutide, which is currently used in the treatment of type 2 diabetes and obesity, might also be an effective medication for alcohol dependence. In a study, the drug reduced alcohol relapse drinking and alcohol intake in rats by more than half.

Semaglutide is sold under brand names such as Ozempic. There is anecdotal evidence of patients with obesity or diabetes saying that their craving for alcohol has lessened since they started taking the drug.

Today, individuals with alcohol dependence are treated with a combination of various psychosocial methods and medications. Four approved medications are available.

Semaglutide is a long-acting substance that patients only need to take once a week. This is the first medication to act on the GLP-1 receptor that can be taken in tablet form.

In the study, alcohol-dependent rats were treated with semaglutide, which significantly reduced their alcohol consumption and even reduced the drinking of alcohol in conjunction with relapses. Relapses comprise a major problem for individuals with alcohol dependence, as an individual who has abstained from alcohol for a period relapses and drinks more than before the withdrawal.

"There are differences in conducting studies on animals and humans. However, in this case, there is a previous study on humans in which an older version of the diabetes medications that act on GLP-1 was found to reduce alcohol intake in overweight individuals with alcohol dependence," says Elisabet Jerlhag.

The study also examined why the medication reduces alcohol drinking. The results indicate that reduced alcohol-induced reward could be a contributing factor. In the study, semaglutide affected the brain's reward system in mice, to be more exact the nucleus accumbens area of the brain, which is part of the limbic system.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: alcohol; ozempic; semaglutide
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A newer diabetes and weight loss drug can cut the attraction to alcohol.

The drug is available today.

1 posted on 06/11/2023 1:10:40 PM PDT by ConservativeMind
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To: ConservativeMind

Cool. Weight loss AND cuts too much boozing.


2 posted on 06/11/2023 1:13:33 PM PDT by Responsibility2nd ( )
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To: ConservativeMind

I find the drug free method to reduce alcohol consumption very effective. Avoid the news and leftists of all sorts and you won’t be driven to drink. It’s also helpful not having a crazy wife.


3 posted on 06/11/2023 1:14:56 PM PDT by ConservativeInPA (Delay Trump’s trial, delay. Elect Trump President. Trump pardons himself.)
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To: ConservativeMind

Why not just reduce the number of times you go to the bar or the number of bottles you buy at the liquor store by half?


4 posted on 06/11/2023 1:16:55 PM PDT by Round Earther
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To: ConservativeMind
Can't help but wonder what the down side is going to be.

With the way they are promoting it I get the impression it is going to be a doozy.

Maybe it makes you vote democrat!

5 posted on 06/11/2023 1:22:34 PM PDT by Harmless Teddy Bear (Follow the money. Even if it leads you to someplace horrible it will still lead you to the truth.)
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To: Harmless Teddy Bear

Covers another recent injection death rate with a noise signal?


6 posted on 06/11/2023 1:24:30 PM PDT by wgmalabama (Censored !)
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To: ConservativeInPA

Not as easy as popping a pill. But it does work. I keep it in the cabinets and in the fridge. But I quit. I still desire it.


7 posted on 06/11/2023 1:25:55 PM PDT by BipolarBob (I was going to start procrastinating this year, I just haven't got around to it.)
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To: Harmless Teddy Bear

I’m sure it’s “safe and effective”.


8 posted on 06/11/2023 1:26:56 PM PDT by BipolarBob (I was going to start procrastinating this year, I just haven't got around to it.)
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To: ConservativeMind

If you want to drink, you will. If you don’t, you won’t. For normal drinkers, the drug may work, but not for addicts.


9 posted on 06/11/2023 1:37:31 PM PDT by peggybac (My will is what I wanted. God's will is what I got.)
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To: peggybac

” For normal drinkers, the drug may work, but not for addicts.”

It worked for addicted mice.


10 posted on 06/11/2023 1:44:49 PM PDT by TexasGator
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To: BipolarBob

“I’m sure it’s “safe and effective”.”

I bet it’s healthy also. It rhymes with Olympic.


11 posted on 06/11/2023 1:46:03 PM PDT by LeoTDB69
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To: LeoTDB69

It comes in four flavors: Summer Strawberry Ozempic, Winter watermelon Ozempic, Spring Starfruit Ozempic and last Fall Fuji Ozempic. Ozempics all year long.


12 posted on 06/11/2023 1:58:56 PM PDT by BipolarBob (I was going to start procrastinating this year, I just haven't got around to it.)
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To: ConservativeMind

They aren’t injecting it instead?


13 posted on 06/11/2023 2:08:41 PM PDT by nickcarraway
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To: ConservativeMind

Great. Let’s make the shortage worse.


14 posted on 06/11/2023 2:25:10 PM PDT by Tacrolimus1mg (Do no harm, but take no sh!t.)
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To: ConservativeMind

Or one could just stop drinking


15 posted on 06/11/2023 2:31:37 PM PDT by Nifster ( I see puppy dogs in the clouds )
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To: Responsibility2nd

Probably no small part of how people lose weight.

I know a guy who used a related drug after a divorce, along with testosterone replacement and serious weight training and walking.

He lost 80lbs in a year. Looks great.

Says he lost 280lbs of dead weight from the divorce.

I know his wife, too. I agree.


16 posted on 06/11/2023 2:38:20 PM PDT by Jewbacca (The residents of Iroquois territory may not determine whether Jews may live in Jerusalem.)
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To: Round Earther

Three beers is 900 calories.

You don’t have to be a drunk to get fat from drinking.

You just have to be bored.


17 posted on 06/11/2023 2:40:14 PM PDT by Jewbacca (The residents of Iroquois territory may not determine whether Jews may live in Jerusalem.)
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To: Nifster

Clearly you have never been a drinker.

Its easier said than done.

I realized that I needed to stop drinking at age 30. But didn’t stop until age 40. Went on the wagon many times.

I had to change cities, lose my drinking buddies and find Jesus in order to stop drinking. All hard but necessary things for me to do.

Totally agree. The problem goes away if you just stop drinking. You can also lose a lot of weight if you just eat less and avoid sugar and refined carbs. No problem. Right?


18 posted on 06/11/2023 2:46:50 PM PDT by ckilmer (ui)
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To: ConservativeMind

.


19 posted on 06/11/2023 3:02:57 PM PDT by sauropod (“If they don’t believe our lies, well, that’s just conspiracy theorist stuff, there.”)
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To: Nifster

Just “put the plug in the jug”?


20 posted on 06/11/2023 3:10:28 PM PDT by Dalberg-Acton
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