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Statins linked to lower risk of colorectal cancer in patients with ulcerative colitis
Medical Xpress / Karolinska Institutet / eClinicalMedicine ^ | Sept. 1, 2023 | Jiangwei Sun et al

Posted on 09/04/2023 1:22:12 PM PDT by ConservativeMind

Cholesterol-lowering statins might protect patients with ulcerative colitis from developing and dying from colorectal cancer. Statin treatment was also associated with a lower risk of death regardless of cause in patients with ulcerative colitis or Crohn's disease. This is according to a study.

"Our study suggests that statins can prevent colorectal cancer in patients with inflammatory bowel disease (IBD), which is a high-risk group for this kind of cancer," says Jiangwei Sun.

The observational study compared more than 10,500 IBD patients from around the country, of whom half were statin users; the other half of the group, who were matched with the first, were not. After a follow-up period of, on average, 5.6 years, 70 of the statin group and 90 of the non-statin group had been diagnosed with colorectal cancer.

The protective effect was directly proportional to the length of time the patient had been on statins and could be demonstrated after two years' treatment.

There were also fewer deaths from colorectal cancer in the statin group (20) than in the non-statin group (37) during the study period, and deaths regardless of cause (529 versus 719).

The study shows that some 200 IBD patients need to be treated with statins to avoid one case of colorectal cancer or death from the cancer within ten years of treatment onset. The protective effect was only statistically valid for patients with ulcerative colitis.

To avoid death regardless of cause during the same ten-year period, the number of treated patients dropped to 20, on account of how statins also protect against more common conditions, such as cardiovascular disease. Statins were linked to fewer deaths in both ulcerative colitis and Crohn's disease patients.

The study was based on the ESPRESSO-cohort.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: colitis; coloncancer; statins; ulcerativecolitis
I would hope that diet which kept cholesterol and such in check would provide a similar benefit, but that was not tested.
1 posted on 09/04/2023 1:22:12 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

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2 posted on 09/04/2023 1:22:43 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Interesting study. As much as I am monitored, anything that will have the potential of being potentially cancerous will be taken out w/out much delay.
Indeed, it has already happened once: a pre-cancerous polyp was found and removed. I doubt my doctor would put me on statins just for that, but you never know…

Thanks for finding and posting this.


3 posted on 09/04/2023 2:24:15 PM PDT by telescope115 (I NEED MY SPACE!!! 🔭)
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To: ConservativeMind

Statins are over prescribed by a lot.

I appear to have beaten UC by drinking a cabbage and fruit juice cocktail made from a juicing machine for about 6 weeks plus filtering all the water I drink. I think it was filtering the water with a high quality filter that really did the trick. I also drink a cup of water with a heaping teaspoon of fiber powder. Nothing special, just the Equate brand from Walmart. It has been 4 months since a flare up so not that long but it was nearly chronic before. My doc wanted to put me on Humira ($6k a month) but I wanted to try my way first. I’m happy to say I believe I found what works for me. Can’t say it will work for everyone but some variation might.

There’s been some articles about how contaminated city water is and that well water is no guarantee for being pure water either. I guess the only way to be sure is to have it tested or use a filtering device to see if anything changes. Tested water might be good when sample is taken but not every day.

This is the filtering device I use: https://www.amazon.com/ZeroWater-Ready-Pour-Dispenser-Filter-Pitcher/dp/B083KY2FZB/ref=sr_1_5?crid=1O539MB9ADHNL&keywords=ZeroWater+20-Cup+Ready-Pour+5-Stage+Water+Filter+Pitcher&qid=1693872986&sprefix=zerowater+20-cup+ready-pour+5-stage+water+filter+pitcher%2Caps%2C253&sr=8-5


4 posted on 09/04/2023 5:24:07 PM PDT by Boomer (X-Twitter is NOT a free speech platform. The scummy Marxists are back in charge. )
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To: ConservativeMind

They are also related to a large number of illnesses and even death.


5 posted on 09/04/2023 5:26:14 PM PDT by Revel
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