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Company Making Fake Urine for Research
Associated Press ^ | Mon, Sep 13, 2004 | DAVID TWIDDY

Posted on 09/13/2004 9:34:58 AM PDT by presidio9

Synthetic urine, which sounds like something more likely to generate snickers than sales, is turning into a small success for a Kansas company.

Dyna-Tek Industries, a company bought by Kevin Dyches and his wife, Sandra, five years ago, has developed synthetic urine for the research industry.

One of their first customers is the Centers for Disease Control and Prevention (news - web sites), which made a big purchase this summer and has hinted it could be a major buyer long into the future. Other research institutions and laboratories are also looking into Dyna-Tek's product, called Surine.

"We have been very blessed with this," said Dyches, who handles finances and marketing for the three-person company, discreetly tucked away in a suburban Kansas City office park. "It was pretty discouraging until about a year ago."

The laboratory industry has a serious need for synthetic urine. Researchers, drug-testing labs and other institutions buy thousands of gallons of the real stuff, mostly to calibrate the equipment used to test regular urine samples for drugs or other substances. Researchers periodically check the accuracy of their equipment by introducing samples that have been intentionally spiked with drugs and other chemicals.

But human urine has its limitations: It decays rapidly if not kept refrigerated and must be frozen when shipped. It can smell, and it foams. Donors must be screened carefully for drug use or disease. Also, different body chemistry guarantees that no two people's urine is exactly alike, an irritation for researchers who rely on consistency.

A fully synthetic urine could eliminate those problems.

"I think in the next few years, synthetic urine will replace human urine" in laboratories, said Fred Klaus, purchasing manager for Redwood Toxicology, a Santa Rosa, Calif., drug testing company that tests about 30,000 urine samples a day and is thinking about testing Surine. "If you end up with something like Surine that's very stable and easy to maintain, you're going to go to that because that's one of your savers."

David Ashley is the chief of the CDC's emergency response and air toxicants branch. His agency bought 33 liters of Surine — but may buy more than 10 times that amount if it works the way they hope it will.

Ashley's agency has a long history of handling human urine, but a new joint program with state health departments for monitoring harmful substances in the environment would require large amounts of urine quickly.

"We're faced with the very large challenge of producing material for all of those labs that will be consistent across the board," Ashley said.

Dyna-Tek is not the first outfit to attempt synthetic urine. Several companies have tried making it, typically ending with products based on human urine but treated with preservatives to reduce some of its problems.

Most of those products have fared poorly in lab tests, said Dr. Robert Willette, president of Denver-based Duo Research and one of the country's foremost experts on drug testing.

"None have been commercially successful," Willette said. "The criteria is it doesn't interfere with the tests, and the labs can't tell the difference."

Willette was one of several experts who advised Dyna-Tek in developing Surine, but he said he has no financial relationship with the company.

"I'm very interested in giving advice, because I want to become a customer," he said. "When you look at all the labs that have to use control samples to calibrate their instruments, there's an enormous potential out there."

There is another, less legitimate potential: Dyches said he has gotten calls from companies that want to sell his product to drug users so they can pass drug tests. He said he rejected those sales and continues to do business only with reputable research labs.

Ultimately, however, he said security is something he'll have to think about, especially if the market for Surine grows and it's harder to keep track of where it goes.

"I don't know how you avoid that," he said.

Dyches said the company, which was started in 1993 by a hospital toxicologist, is still small, with less than $500,000 in annual sales. Its main business is selling glass test tubes and evaporator cups used in manual and automated drug testing.

While Surine brings in just 7 percent of revenue, Dyches said, "I'd be disappointed if in five years that isn't 90 percent of sales." Right now, sales are in such an early stage that a price for the product has not been set.

Dyna-Tek had been tinkering with formulas for synthetic urine since the days before the Dyches couple bought it. The breakthrough, operations manager Susan Olsen says, was when the company determined how to keep Surine stable during tests involving tetrahydrocannabinol, or THC, the chemical compound in marijuana that gets people high.

THC is one of the chemicals Surine would be spiked with, to use as a control in testing people's urine. THC decays rapidly in regular urine if not kept cold, limiting the usefulness of most urine-based control products being shipped long distances.

In addition, drug enforcement agencies are calling for more companies to do drug testing at the work site, as opposed to mailing samples to a lab. With employees who may not have scientific training doing the tests, companies will want a more rugged product that doesn't require much coddling, Dyches said.

Dyches said he also is getting phone calls from industries outside of drug testing, such as a manufacturer that makes adult diapers.

"We're finding lots of applications for it that we didn't know existed," he said.

___


TOPICS: Culture/Society
KEYWORDS: albertpujols; barrybonds; jasongiambi; riker; sammysosa; urine
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1 posted on 09/13/2004 9:34:58 AM PDT by presidio9
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To: presidio9
............this is going to be the best thread ever.
2 posted on 09/13/2004 9:36:00 AM PDT by Psycho_Bunny
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To: presidio9

Getting rich making fake pee.
What a country!


3 posted on 09/13/2004 9:37:23 AM PDT by gutshot
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To: Psycho_Bunny

Wifey just this weekend bought some "Flexitol" skin balm for dry heels....I read the ingredients and had the pleasure of advising her that what she was rubbing into her wheels was 25% pee......I assume that's what Urea is!


4 posted on 09/13/2004 9:38:05 AM PDT by ErnBatavia ("Dork"; a 60's term for a 60's kinda guy: JFK)
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To: presidio9

Great news for working druggies everywhere...

This really PISSES me off.


5 posted on 09/13/2004 9:38:14 AM PDT by Trampled by Lambs ("Making Al Gore regret inventing the internet, one post at a time")
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To: presidio9
Sales to individuals subject to drug tests shold go through the roof!

Yeah, I'll fill the cup, but you'll have to turn your head...

6 posted on 09/13/2004 9:39:14 AM PDT by Lurking2Long
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To: presidio9
Betcha they're insured by Allstate:   'You're In' Good Hands With Allstate.
7 posted on 09/13/2004 9:42:00 AM PDT by jigsaw (God Bless Our Troops!)
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To: Psycho_Bunny

#1


8 posted on 09/13/2004 9:44:18 AM PDT by presidio9 (Can I borrow your underpants for five minutes?)
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To: presidio9

Will Albert Pujols now start buying this stuff, instead of peeing on his hands?


9 posted on 09/13/2004 9:46:08 AM PDT by Fedupwithit ("Expend all remaining within my perimeter!"..a MA FReeper sacrificing himself)
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To: presidio9

Let's celebrate thier good fortune by drinking a non-alcohol beer!!!

We'll all eat tofu snacks!!!


10 posted on 09/13/2004 9:47:00 AM PDT by baltodog ("Anaerobic Putrification" is my favorite funeral term...)
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To: presidio9
Skeeter's recipe for pee:

1/2 oz Cointreau
1 oz Vodka
Juice of 1/2 Limes
1 splash Cranberry Juice
stir

11 posted on 09/13/2004 9:47:09 AM PDT by skeeter
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To: Fedupwithit

Actually, among MLB players, the target market for fake urine is more likely to be Barry Bonds, Jason Giambi, and Sammy Sosa.


12 posted on 09/13/2004 9:47:24 AM PDT by presidio9 (Can I borrow your underpants for five minutes?)
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To: presidio9

Shows you what I know. I never would have guessed that real urine was in such short supply...


13 posted on 09/13/2004 9:49:43 AM PDT by pabianice
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To: presidio9

So what does that make Picard?


14 posted on 09/13/2004 9:56:45 AM PDT by fishtank
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To: presidio9

If different body chemistry guarantees that no two people's urine is exactly alike, how is synthetic urine a valid reference for anyone?


15 posted on 09/13/2004 9:59:33 AM PDT by stuartcr (Neither - Nor in '04....Who ya gonna hate in '08)
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To: presidio9

Is this company owned by VIACOM? or VIA-CON?


16 posted on 09/13/2004 10:02:19 AM PDT by Red Badger (Kerry can't run on his record, so George Bush is going to.....)
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To: pabianice
"Shows you what I know. I never would have guessed that real urine was in such short supply..."

It's not but standardized urine is. I used to work in a lab that did drug testing for law enforcement. You need a surprising amount just to calibrate equipment. Lab people have hoping for fake urine for a long time.

As for the illegal usages, well, it's a problem but one that can probably be solved pretty easily. The addition of an inert chemical "marker" would do it. Sort of like adding a VIN number. Tests and equipment would have to detect the marker but that's not an insurmountable barrier.

As someone who has cleaned up and autoclaved her share "pee", I applaud anything to spare future lab people the horror.

17 posted on 09/13/2004 10:06:14 AM PDT by Gingersnap
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To: fishtank

Typical wimpy Frog who has no business commanding a starship.


18 posted on 09/13/2004 10:06:43 AM PDT by presidio9 (Can I borrow your underpants for five minutes?)
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To: presidio9

To be serious ...

"...different body chemistry guarantees that no two people's urine is exactly alike, an irritation for researchers who rely on consistency."

What does THAT tell you about the reliability of urine tests now being used?

What does that tell you what the reliability of future test will be if they use synthetic (unvarying) urine as their research base? The results on REAL people will be even more unreliable.


19 posted on 09/13/2004 10:24:54 AM PDT by steplock
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To: presidio9

I remember a company that was producing a synthetic baby poop for use in the testing of diapers. The objects was to have a standard reproducible poop that would not be hazardous to the diaper testers.


20 posted on 09/13/2004 10:27:33 AM PDT by Vinnie_Vidi_Vici
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