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Adult brain cells made to multiply and regenerate
NewScientist.com news service ^ | 18 August 2006 | Helen Thomson

Posted on 08/20/2006 1:53:07 AM PDT by neverdem

Adult human brain cells can generate new tissue when implanted into in the brains of mice, new research reveals. The findings could pave the way to new therapies for a host of neurodegenerative diseases, including Alzheimer’s, the researchers say.

Furthermore, lab tests show that the mature brain cells have the versatility to divide many times in culture and develop into a wide range of specialised cell types.

Researchers at the University of Florida, US, showed for the first time that common human brain cells are adaptable and self-renewing – qualities normally associated with stem cells.

Dennis Steindler and his colleagues transplanted adult human brain cells into mice and found that they could successfully generate new neurons and incorporate themselves in a variety of brain regions.

The researchers also coaxed a single adult brain cell to divide into millions of new cells in culture. “We can, theoretically, take a single brain cell out of a human being and generate enough brain cells to replace every cell of the donor’s brain,” says Steindler.

Brain donor

The new source of human brain cells could be used to repair or replace damaged tissue in degenerative disorders such as Alzheimer’s and Parkinson’s disease, the researchers suggest.

“Anything that removes the need to use foetal or embryonic tissue [to clone new tissue] is very interesting because that’s where the controversy lies,” says David Dexter, a specialist in Parkinson’s disease at Imperial College, London, UK, who was not involved in the study.

(Excerpt) Read more at newscientist.com ...


TOPICS: Culture/Society; Extended News; News/Current Events; US: Florida; United Kingdom
KEYWORDS: brain; chimera; health; science
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Journal reference: Development (vol 133, p 3671)
1 posted on 08/20/2006 1:53:08 AM PDT by neverdem
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To: neverdem

Good. See to it that the entire democratic party gets a refill. Might make a few more republicans that way.


2 posted on 08/20/2006 2:08:20 AM PDT by Wombat101 (Islam: Turning everything it touches to Shi'ite since 632 AD...)
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To: neverdem

Ah then their is hope for Political Leftists yet. It may be possible their stupidity is not terminal. Of course it is probable a mouse brain will be far too large for their pin sized heads. We can hope that with time, Science may find a process to miniatures down to a flea bran so that the transplantable brain will be small enough to fit a Leftist's head.


3 posted on 08/20/2006 2:13:51 AM PDT by MNJohnnie (History shows us that if you are not willing to fight, you better be prepared to die)
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To: neverdem
A mouse brain? "See, Pinky, we are one step closer to world domination!"
4 posted on 08/20/2006 2:18:11 AM PDT by Smokin' Joe (How often God must weep at humans' folly.)
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To: neverdem

Whew! For a second, I thought the author's name was Helen Thomas!

(no HT pics please)


5 posted on 08/20/2006 2:20:58 AM PDT by JillValentine (Being a feminist is all about being a victim. Being an armed woman is all about not being a victim.)
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To: neverdem

The Scarecrow will be in deep gratitude, to the Wizard of Oz. Now, if I only had a brain...


6 posted on 08/20/2006 2:23:17 AM PDT by Treader (Human convenience is always on the edge of a breakthrough, or a sellout)
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To: El Gato; Ernest_at_the_Beach; Robert A. Cook, PE; lepton; LadyDoc; jb6; tiamat; PGalt; Dianna; ...
It seems that mice don't have problems with immunological rejection.

Study Shows Cancer Cells May Revert

How Human Cells Get Their Marching Orders

FReepmail me if you want on or off my health and science ping list, or the much more selective stem cell list.

7 posted on 08/20/2006 2:26:08 AM PDT by neverdem (May you be in heaven a half hour before the devil knows that you're dead.)
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To: Mr. Silverback

prolife ping


8 posted on 08/20/2006 2:30:32 AM PDT by Treader (Human convenience is always on the edge of a breakthrough, or a sellout)
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To: Coleus; Peach; airborne; Asphalt; Dr. Scarpetta; I'm ALL Right!; StAnDeliver; ovrtaxt; MHGinTN; ...

Ping


9 posted on 08/20/2006 2:33:59 AM PDT by neverdem (May you be in heaven a half hour before the devil knows that you're dead.)
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To: neverdem

Are you thinking what I'm thinking? That we might be creating a race of super mice that will one day take over the world?

10 posted on 08/20/2006 2:35:00 AM PDT by Rightwing Conspiratr1
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To: neverdem
I was tought that brain cells were a finite amount determined at birth. Use of alcohol, drugs, etc. diminished them and you could never get them back according to the teaching.

If human brain cells are regenerative or can keep reproducing then intelligence can be gained over a period of time for anyone.

I doubt this is the case, though.

We had an exercise in grade school where we drew a circle with a pencil, then we attempted to put as many dots into the circle with our pencil in the course of a minute.

We could not add dots after the time was up. The circle represented our brain, the dots were our brain cells. We had to erase multiple dots representing years of drug/alcohol abuse. Eventually, your brain became theoretically 'fried' once a certain amount of dots were erased.

All of this was to represent that brain cells could only be lost, not regenerated or reproduced.
11 posted on 08/20/2006 2:52:24 AM PDT by lmr (You can have my Tactical Nuclear Weapons when you pry them from my cold dead fingers.)
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Comment #12 Removed by Moderator

To: neverdem

Yes, reading Free Republic reverses brain damage!
(oh, that isn't what the article's about? Well, it's true anyway!)


13 posted on 08/20/2006 3:55:06 AM PDT by ClaudiusI
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To: lmr

The human brain is vastly unknown. You were taught what was known and theorized at the time.


14 posted on 08/20/2006 4:09:05 AM PDT by visualops (artlife.us)
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To: neverdem

Excellent, nd.

Thank you. Hope for all of us! Be interesting to see what happens in the development track with this and the Alzheimer's and like vaccines.

Thanks, again.


15 posted on 08/20/2006 5:54:27 AM PDT by HonestConservative ((It's SNOWING!))
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To: neverdem; potlatch; ntnychik; Smartass; Boazo; Alamo-Girl; PhilDragoo; The Spirit Of Allegiance; ...

kin ah git me some a these here brain cells - ping


16 posted on 08/20/2006 8:20:14 AM PDT by bitt ("And an angel still rides in the whirlwind and directs this storm.")
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To: bitt

Brain cells are touchy things. If they have other brain cells to regenerate with, they might cooperate. And that leaves Kerry, among others, out in the cold.


17 posted on 08/20/2006 8:22:55 AM PDT by Enterprise (Let's not enforce laws that are already on the books, let's just write new laws we won't enforce.)
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To: neverdem; AntiGuv

good. ping.


18 posted on 08/20/2006 10:51:22 AM PDT by King Prout (many complain I am overly literal... this would not be a problem if fewer people were under-precise)
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To: bitt

Git 'er done!


19 posted on 08/20/2006 11:02:48 AM PDT by MHGinTN (If you can read this, you've had life support from someone. Promote life support for others.)
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To: Rightwing Conspiratr1
Are you thinking what I'm thinking? That we might be creating a race of super mice that will one day take over the world?

Oh, no, deja vu one more time. Remember Michael Jackson singing an Academy Award nominated song back in 1972?

"Ben, most people would turn you away,
I don't listen to a word they say..."


20 posted on 08/20/2006 11:31:05 AM PDT by xJones
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