Cut all spending by 10% that’s a start. A dime out of every dollar. One out of ten employees.
Discretionary spending is shrinking as a percentage of the budget. We are so far in debt that service on the debt is growing rapidly. That leaves Defense, Social Security and Medicaid/Medicare as by far the largest portion of Fed.gov spending. Those will not be touched.
Take an ax to Dept. of Education and a host of other agencies for ideological reasons, but it won't make a huge dent in government spending.