Posted on 10/07/2018 6:40:13 PM PDT by ConservativeMind
Early signs of type 2 diabetes can be identified more than 20 years before diagnosis, according to new research presented at this year's European Association for the Study of Diabetes (EASD) Annual Meeting in Berlin, Germany (1-5 October).
The Japanese study tracked over 27,000 non-diabetic adults (average age 49 years) between 2005 and 2016 and found that increased fasting glucose, higher body mass index (BMI) and impaired insulin sensitivity were detectable up to 10 years before the diagnosis of diabetes as well as prediabetes.
[snip]
"As the vast majority of people with type 2 diabetes go through the stage of prediabetes, our findings suggest that elevated metabolic markers for diabetes are detectable more than 20 years before its diagnosis," says Dr Hiroyuki Sagesaka from Aizawa Hospital in Matsumoto, Japan.
[snip]
In particular, BMI, fasting glucose, and insulin resistance were increased up to 10 years before diagnosis, and these differences widened over time.
(Excerpt) Read more at sciencedaily.com ...
Ok.....
Basically, diabetus melitus or type two diabetes, has no symptoms.
Except perhaps there are symptoms that seem un related. One is heartburn. That is a digestive disorder that is related to over production of acids. Another is night drooling. Drooling might be related to indigestion as the body at rest attempts to compensate for the acid by producing silava. A third is waking at 3 AM. It is said that when the carb load is digested, that produces metabolic change that results in awakening.
I had all these events from ten to thirty years before being diagnosed with type 2 diabetes. The actual diagnosis was not based on any symptoms but rather pure numbers. At the time in 2008, a fasting blood sugar lab result of 140 or greater twice within a 6 month interval. There was a corresponding A1c number that I believe was >5.7 or 5.8. I don’t remember.
On receiving the diagnosis and being told to reduce carbs and end sweets, loose weight and exercise, I studied the problem.
I learned that soon begore the diagnosis the lower blood sugar reading was 126. I was never able to determine why precisely the threshold number was raised.
The most important factor for me to control the condition was weight loss. Later as I aged, the numbers crept up and I was prescribed metformin. Those noted events dissapated or went away. I had an A1c ,6.5 and the doctor was satisfied. I actually felt better.
Diabetes type 2 is an incurable condition. It is for life. It can be controlled by maintaining a diet of few carbs, exercise and maintianing a stable reduced weight. At least, that is my experience.
Although the data was not collected or measured, spending excess time arguing on Free Republic seems to have no effect on the disease
Not true. I’ve met many skinny type 1 diabetics.
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TYwo completly opposite diseases.
Type 1 = Pancreas fails to produce the hormone insulin because of damage to the insulin cells. Insulin injections are needed to replace the insulin.
Type 2 is caused by the overproduction of insulin causing insulin resistance. This causes glucose to be stored as fat. Adding insulin injections causes even more damage
Two completely opposite diseases treated one way.
Type 2 is a dietary disease, not a hormonal disease. You don’t fix dietary diseases with medication
Diabetes type 2 is an incurable condition. It is for life. It can be controlled by maintaining a diet of few carbs, exercise and maintianing a stable reduced weight. At least, that is my experience.
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Completely false. It has been proven to be cured by diet. If it is treated with medication, as is now the norm, yes, it will be incurable.
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The symptoms and numbers change but the condition remains
Not eating trans your metabolism to hunker down. Train your metabolism to process fats and proteins and the weight comes off without starving. Say goodbye to carbs, however.
If you are 150 pounds overweight you need to stop eating. Your body needs to hunker down. I have seen people do it. Much safer than surgery.
No, actually, you shouldn’t. The science is now conclusive. Training your body to consume fat/protein first is the safest way to diet.
If you stop eating, your body will respond by shutting down the metabolism.
The ONLY downsides to a keto diet is a) initially, the level of ketones in your blood will result in urinating more often and sometimes some headaches and b) making sure there is enough variety in your diet that you don’t go back to carbs.
The giant upside - no starvation.
An effective calorie restriction diet becomes effective because it becomes naturally ketogenic. The body stops living on foods, and starts living on stored adipose fat.
This fact should convince anyone that ingesting fats instead of carbs is a more valid method of weight loss and glucose control. We don’t store fats as carbs. We store carbs as fat.
Apparently, there is some evidence that Type 2 is autoimmune, but a very different set of targets than Type 1.
Wheat Gliadin peptide A5 has been found in pancreases of type 1 diabetics as have antibodies to A5. A5 mimics beta endorphin.
The pancreas monitors and holds endorphin, and secretes insulin in response. The insulin prevents muscles from consuming themselves in fight-or-flight situations.
Some immune systems recognize A5 as an invading antigen, and attack the pancreas. This does not mean that other carb proteins don’t mimic endorphin and cause the same autoimmune response. Gliadin A5 is just the best studied one.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4119241/
I hate waiting in lines soooo in the Navy back in the 70’s I started One Meal per day and it just became normal and I’m never hungry, I actually have to remember to eat.
But these days I seem to get the majority of my calories from beer anyway
It would not surprise me to find that many people develop antibodies against the carb lectins which attack cellular insulin receptors and develop antibodies against the receptors themselves.
Amen. Preach it.
The symptoms and numbers change but the condition remains
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My brother was type-2 diabetic using insulin to control glucose.
He had bariatric surgery 4 years ago and has been off all medication since, and his numbers remain normal.
I’ll be sure to tell him he still has the disease.
FWIW. nearly 95% of people having bariatric surgery no longer suffer from the disease. How is that if the disease is not curable, only treatable? You keep telling yourself it can’t be cured, only managed. Big Pharma loves you!
The carb lectins which cause t2 diabetes would normally be too big to transport from the small intestine into the bloodstream. With age people set up intestinal immune reactions. These reactions cause zonulin release. Zonulin defeats the “tight junctions” between intestinal lining cells. Partially digested intestinal lumen flows into the bloodstream including large lectins. This process takes place in the small intestine’s headwaters. Over time this area becomes more porous. The surgery you refer to removes this section of intestine. Most people who get it experience a marked reduction in metabolic and autoimmune symptoms. Without initiating a ketogenic diet though, symptoms usually return.
Over time this area becomes more porous. The surgery you refer to removes this section of intestine.
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He had gastric sleeve, not bypass.
Is your type-2 really type 1.5? Look into LADA (latent autoimmune diabetes in adults).
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