Posted on 02/16/2020 9:15:58 PM PST by Bon mots
What is your risk to get infected coronavirus?
East Asians, Japanese, and Han Chinese are the most likely people to become severely sick by the coronavirus with a chance of more than 90% when exposed. Europeans only rank in the 50%, Africans in the 60% range, and considered low to medium. It also makes a difference if one is a smoker or non-smoker.
The Travel and Tourism industry is in turmoil. Tourism leaders don’t want anyone to panic, but the story doesn’t yet have an end to it.
At the same time, researchers are working around the clock to learn more about the deadly virus. Recent studies may explain why Europe, America had no deadly cases of the virus, and no coronavirus cases at all were reported from Africa.
Stopping travel may not be the solution and could only mean travel businesses could become collateral damage in the fight against coronavirus. The World Health Organization always said “do not stop travel and commerce.”, even after WHO declared a global epidemic emergency.
Why is this?
The novel coronavirus (2019-nCov) was identified in Wuhan, Hubei Province, China in December of 2019.
This new coronavirus has resulted in thousands of cases of lethal disease in China, with additional patients being identified in a rapidly growing number internationally.
2019-nCov was reported to share the same receptor, Angiotensin-converting enzyme 2 (ACE2), with SARS-Cov.
Here based on the public database and the state-of-the-art single-cell RNA-Seq technique, the ACE2 RNA expression profile in the normal human lungs. The result indicates that the ACE2 virus receptor expression is concentrated in a small population of type II alveolar cells (AT2).
Surprisingly, studies found that this population of ACE2-expressing AT2 also highly expressed many other genes that positively regulating viral reproduction and transmission.
A comparison between eight individual samples demonstrated that the Asian male one has an extremely large number of ACE2-expressing cells in the lung. This is based on an unfinished study by Yu Zhao, Zixian Zhao, Yujia Wang, Yueqing Zhou, Yu Ma, Wei Zuo and published by Bio Rxiv:
A second study investigates how and why the virus will enter the human body, by Michael Letko, Vincent Munster
Apparently the coronavirus enters a human body through some connection with something called the ACE2 receptor. East Asians and men have more than say white Europeans and women. Being a white woman seems to be the way to have much lesser risk.
According to this study and based on the assumption in this study and in regards to the receptor, Angiotensin-converting enzyme 2, human populations where samples were available were categorized by risk in obtaining a dangerous version of the virus. Most ill may not feel more than a common cold, for others Coronavirus can be fatal.
According to this preliminary study the risk of obtaining the virus:
High risk 90%-99%
Japanese in Tokyo, Japan
Southern Han Chinese
Kinh in Ho Chi Minh City, Vietnam
Han Chinese in Bejing, China
Chinese Dai in Xishuangbanna, China
Moderate Risk: 80-89%
Not found
Medium to Moderate Risk: 70-79%
Peruvians from Lima, Peru
Bengali from Bangladesh
Sri Lankan Tamil from the UK
Indian Telgu from the UK
Mexican Ancestry from Los Angeles, USA
South Asians (general average)
Medium Risk: 60-69%
Gujarati Indians from Houston, TX
Admixed Americans
Americans of African Ancestry in SW USA
Punjabi from Lahore, Pakistan
African Caribbeans in Barbados
Luhya in Webuye, Kenya
Mende in Sierra Leona
Africans (general average)
Esan in Nigeria
British in U.K.
Gambians in Western Division in The Gambia
Puerto Ricans
Low to Medium Risk: 50-59%
Colombians from Medellin
Yoruba in Ibadan, Nigeria
Finnish in Finland
Iberian Population in Spain
Europeans (in General)
Utah Residence (Caucasians)
Toscani, Italy
Interesting to note that it appears to be deadliest to smokers - some 74% of Chinese men smoke, while less than 10% of Chinese women do.
Looks like a lot of folks should have chosen their parents better.
At least Michael Jackson will be safe ...
Gujarti Indians from Houston????
The yellow virus! A racist one at that.
Are there a lot of Gujarti Indians in Houston?
I would strongly suggest Dr. Tedros from WHO is the modern Bagdad Bob. Every time he opens his mouth you can visualize the shit falling out.
If you don’t know the answer off of the top of your head, then you don’t deserve to know.
In fact, I don’t think I can post to you anymore.
The answer is 56.253
Sheesh
:)
I would not put too much emphasis on this yet, but it in interesting.
For example, why is Utah considered lower risk than England?
This all seems a bit out there, to me.
So, the studies are at odds with each other, but understanding the totality of the infected people and those who experienced the same environment but have not gotten infected seems the more reliable way to know.
I would suspect there are since this assessed risk is not just based on race but where they are located. Don’t see anything about white males of European descent in Atlanta GA so I am safe. :)
It purports to be based upon genetics.
74% of Chinese men smoke, 10% Of Chinese women smoke, and 100% of city dwelling Chinese breath polluted air.
Was this a pandamic weapon developed to be used against the people of Taiwan?
https://en.wikipedia.org/wiki/Han_Chinese
from link:
In Taiwan they (Han Chinese) make about 95% of the population.
NYC, LA and Boston yes. Not sure about Houston.
Well, I did a DNA analysis via 23andMe and it is amazing how precise they can be with geography.
They knew nothing about me but just had some spit in a tube.
They correctly identified the geographic location of my grandfather’s village! They did the same for my mom - we thought it was wrong, but later found out that it was right and my mom’s information about her origins was wrong.
They can see markers and genes and identify where they come from and where they are prevalent.
My guess is that this work looked at where these receptors were most and/or least prevalent.
It seems Europeans and Africans are immune to a lot more pathogens - perhaps due to the fact that both were exposed to tons of plagues over the millenia...
Anyway, thought it was interesting so posted it... food for thought for us armchair medical researchers and epidemiologists... :)
It is interesting.
Thanks for posting.
Why does it give location as well then? Gujarti Indians aren’t indigenous to Houston Texas.
Utah....not much interbreeding among Mormons.
they are whiter than white.
Exactly my point. You’d think that Gujarti Indians in India would have the same risk as Gujarti Indians in Houston.
Angiotensin-converting enzyme
Just about every male over 60 knows about this, as an ACE-inhibitor is used to treat hypertension. I’m taking lisinopril, and it works fine with few side effects now that I’ve been on it for a couple of years. I had rashes and flaking skin after I started, but that went away. Some people can’t tolerate it because it makes them cough.
There are ACE-receptor blockers, but they work on Type 1 receptors, and this virus seems to target Type 2 receptors. Otherwise, a receptor blocker would be a good way to keep the virus from attaching to the target cell.
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