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The quest for longer-lasting Covid-19 vaccines
CNN via MSN ^ | May 20, 2022 | Brenda Goodman

Posted on 05/21/2022 5:40:08 AM PDT by DoodleBob

As waves of new coronavirus variants circulate the globe, one thing has become clear: human immunity against the virus fades over time....But some of the nuances around why and how immunity against Covid-19 fades remain a mystery.

The steepest drops in immunity – which come about four to five months after vaccination and up to eight months after infection, but can vary – are against Covid-19 symptoms, getting infected and getting sick. Protection against severe outcomes, hospitalization and death remains much higher for a longer period of time, but even this decays to some degree, especially for the elderly and those with compromised immune function.

...

“There have been a few side-by-side studies that have compared the mRNA vaccines to infection-induced immunity, and it seems like it slips a little bit faster than that,” Bhattacharya said.

Though he cautioned that protection after an infection varies greatly from person to person just because everyone’s immune system is a little different. There’s no good way to know, right now, how well any particular person’s immune system responds to a vaccine, which is why it’s important to be vaccinated, even if you’ve already had Covid-19.

...

Some vaccines use extra ingredients, called adjuvants, to hyperstimulate the immune system, which increases the strength of the protection people get from them...Fauci said... the nanoparticles being built into some experimental vaccines are an example of this..."Maybe if we use this mRNA, but add a different adjuvant with it, you might get a really good response, the best of both worlds, you might get the real advantage of an mRNA together with a bit more durability, if you add to it an adjuvant as opposed to having the molecule itself be inherently adjuvant.”

(Excerpt) Read more at msn.com ...


TOPICS: Culture/Society; Government; News/Current Events
KEYWORDS: brendagoodman; covid; covid19; newwaves; scamdemic; serge; stuckonstupid; surge; thecoofgrift; thecovidgrift; vaccines
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They're literally making this up as we go along.

The shots were released under EUAs, in part, because there wasn't the usual 2-10 year clinical trial period AND because of the hysteria. The short term trials were just that...trials that ran for a few week under the usual data collection protocols.

Now we see that -surprise - efficacy decays over time for these shots, We also see side effects - maybe due to the messenger RNA platform - and the impacts across multiple seasons.

And now, I'm supposed to worry about the monkeypox?


1 posted on 05/21/2022 5:40:08 AM PDT by DoodleBob
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To: DoodleBob
Headline should read: The Quest for a Covid Vaxx that will Kill More Efficiently.
2 posted on 05/21/2022 5:43:59 AM PDT by HandBasketHell
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To: DoodleBob
More Covid, CNN-MSN .....

Does one really need to read to smell .....


3 posted on 05/21/2022 5:57:25 AM PDT by Hostage (Article V)
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To: DoodleBob
“COVID” is their new “global warming” and “systemic racism”. It will never go away, it will always be a threat to everyone’s existence, and only by your compliance and sacrifice can you be saved from this terrible threat.

And when/if they ever finally bleed the “COVID” fraud dry, they’ll just substitute some other lie in its place (I guess monkeypox is the new one they’re trying to run with.

4 posted on 05/21/2022 6:01:11 AM PDT by Sicon ("All animals are equal, but some animals are more equal than others." - G. Orwell)
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To: HandBasketHell
They already succeeded..

Death from the vaxx lasts a long time.

5 posted on 05/21/2022 6:05:48 AM PDT by airborne (Thank you Rush for helping me find FreeRepublic! )
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To: DoodleBob

“The quest for longer-lasting Covid-19 vaccines”

First they have to find one that actually works without harm. Their only quest for this right now is if they can find one that keeps the public in fear by lying about its success.

wy69


6 posted on 05/21/2022 6:07:13 AM PDT by whitney69
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To: DoodleBob

“....which is why it’s important to be vaccinated, even if you’ve already had Covid-19.”

And why in the hell would I want to do that if my au naturel immune system has already kicked it’s azz 3 times?

No thanks.... not wrecking a perfectly functional immune system because of you know, the science.


7 posted on 05/21/2022 6:10:36 AM PDT by LastDayz (A blunt and brazen Texan. I will not be assimilated.)
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To: airborne

irborne wrote: “Death from the vaxx lasts a long time.”

Approximately as long as death from the virus but one is far less likely to die from the vaccine.


8 posted on 05/21/2022 6:11:48 AM PDT by DugwayDuke (Most pick the expert who says the things they agree with.)
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To: whitney69

whitney69 wrote: “First they have to find one that actually works without harm. Their only quest for this right now is if they can find one that keeps the public in fear by lying about its success.”

Are you aware of any vaccines that do not have side-effects (harm)?


9 posted on 05/21/2022 6:17:38 AM PDT by DugwayDuke (Most pick the expert who says the things they agree with.)
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To: DoodleBob

The article asserts that immunity slips among those who acquired it via infection. Why should anyone believe that?


10 posted on 05/21/2022 6:18:05 AM PDT by TalBlack (We have a Christian duty and a patriotic duty. God help us.)
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To: DoodleBob

The unknowns are known. Since we are all getting vaccinated at different times...COVID will NEVER go away. <P<Bottom line...if you’re sick...test yourself....


11 posted on 05/21/2022 6:21:38 AM PDT by Sacajaweau ( )
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To: DugwayDuke
one is far less likely to die from the vaccine.

...or maybe not.

I've written this previously, but I think it's worth repeating...

One of the most vital and important (yet perhaps boring) elements in legitimate clinical trials, is the consistent, routine, accurate, and timely collection and recording of side-effect and efficacy data. Trials usually run from two to ten years, with meaningfully large test and control groups. Indeed, the FDA's own websites clearly state that "It's the clinical trials that take so long--usually several years," says Sandra Kweder, M.D., deputy director of the Office of New Drugs in the CDER.

With all this data being collected soberly, a full assessment of the benefits AND side effects can be determined. Things like adverse effects, fatalities, and the like can be observed AND recorded and also vetted (maybe Bob wasn't killed by the shot...or maybe he was).

Not only that, the long time-series of data allows not just for an immediate calculation of vaccine efficacy (VE) but the observation of VE over time, to see if the impact decays and with what kind of pattern (good for a long time then a speedy drop, gradual decline, immediate drop etc).

That's what should have happened with these shots.

Instead, we got a few months of testing, a high VE, and the "all clear" for EUA. The EUA was not fully explained in the context I provided, with a strong caveat emptor warning. Anyone who offered the context I provided was an "antivaxxer."

Then we got reports of bad side effects, sickness, and tragically fatalities. Here is where the absence of controlled clinical trials was revealed: there was NO centralized, homogeneous, controlled collection of these side-effects. It was chiefly citizen reporting, requiring the development of citizen databases...a sort of Nachumlist for shots.

Because this very quickly descended into political science vs medical science, anyone voicing concern about these shots on the basis of this citizen reporting was demonized. What made many people realize this was political science, was that just a few months earlier, "respected" people like Christine Grady ( Fauci's wife) were saying basically the same things, e.g., circa February 2021-

57:26 “…should COVID vaccines be mandated for healthcare providers?” My response is the following…in many healthcare institutions, healthcare workers are required to take flu vaccines…in order to take care of patients, in order to protect the patients. I think that…where we are in the history of this pandemic, I don’t think mandating is the right choice at this point, for several reasons. We still more data…the two vaccines that are being distributed are under an Emergency Use Authorization – they are not approved vaccines (emphasis from Dr. Grady)…and there is this background of concern about politicization…and distrust…that I think it's a mistake to force people to take it. So I don’t think we should be mandating vaccines.

We...ain't that a kick in the head!?!

Fast-forward to today...we have most of the nation (if not planet) having received shots or natural immunity, and no legitimate, controlled long-term clinical trial. There is now statistical evidence of VE waning over a few months, necessitating boosters. We had media stories happily chirping when the unvaxxed die of the virus, goalpost moving re: lying that the shots were all about lessened symptoms when they were only approved for PREVENTION.

I'll say it again: this isn't the flu. This is a nasty virus that can f you up, especially if you have comorbidities and are in an advanced age bracket. If you want to get the shot on medical grounds, I will never call you a sheep. Optimizing your medial utility curve to is YOUR business, not mine. Further, if you are forced to get it on employment/financial grounds, while there are always options I will never call you names if you take the plunge.

Alternatively, there is PLENTY of evidence to wonder just what is the long-run cost/benefit analysis of these shots, and we aren't even 18 months into the effective uncontrolled clinical trial of these messenger RNA shots.

Maybe you're right. Maybe the shots will ultimately turn out to be ok. But to declare a win at the bottom of the second inning is ill-advised.

12 posted on 05/21/2022 6:25:32 AM PDT by DoodleBob (Gravity's waiting period is about 9.8 m/s^2)
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To: DoodleBob
We can't cure the common cold - this is the axiom that has been true forever and is still true.

We are resorting to Mad Scientists to "cure" this illness. Not Good.

13 posted on 05/21/2022 6:27:33 AM PDT by frogjerk (I will not do business with fascists)
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To: DoodleBob

I would submit at this point that the goal should be to find a vaccine that does not outlast the vaccinated.


14 posted on 05/21/2022 6:29:22 AM PDT by Caipirabob (Communists...Socialists...Fascists & AntiFa...Democrats...Traitors... Who can tell the difference?)
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To: HandBasketHell

They’ll need a mark on the hand or forehead to let authorities know who has had this new “vaccine”.


15 posted on 05/21/2022 6:30:05 AM PDT by Rurudyne (Standup Philosopher)
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To: DoodleBob
As waves of new coronavirus variants circulate the globe, one thing has become clear: human immunity against the virus fades over time...

So that they can conveniently trot their pet virus out whenever there’s a big election coming up.

16 posted on 05/21/2022 6:32:42 AM PDT by Allegra
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To: DoodleBob
when they were only approved for PREVENTION.

This bears repeating over and over and over again. Also, where the hell is Comirnaty? It's 2022 and it is supposed to be out.

The government is using trickery of the EUA to force their political/medical will on the populace. Very evil.

17 posted on 05/21/2022 6:33:08 AM PDT by frogjerk (I will not do business with fascists)
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To: DoodleBob

Think of what they want people to believe about this “ vaccine”

It doesn’t stop transmission and some data points to increasing the chance

It doesn’t stop mild or moderate illness, but definitely prevents severe outcomes

It quickly fades in “protection” more so after repeated boosters

It was quickly developed and we have no long term studies

This is nuts


18 posted on 05/21/2022 6:33:33 AM PDT by ALX
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To: DoodleBob

DoodleBob wrote: “I’ve written this previously, but I think it’s worth repeating...One of the most vital and important (yet perhaps boring) elements in legitimate clinical trials, is the consistent, routine, accurate, and timely collection and recording of side-effect and efficacy data. Trials usually run from two to ten years, with meaningfully large test and control groups.”

And this also bears repeating. COVID has killed over 1 Million in the USA alone. Waiting for additional data has it’s costs as well. Waiting for ten years for larger/longer trials might result in another 5 million deaths. The effects world wide might exceed 30 million deaths. Waiting for another ten years is not a free lunch.


19 posted on 05/21/2022 6:35:09 AM PDT by DugwayDuke (Most pick the expert who says the things they agree with.)
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To: DoodleBob

Though he cautioned that protection after an infection varies greatly from person to person just because everyone’s immune system is a little different. There’s no good way to know, right now, how well any particular person’s immune system responds to a vaccine, which is why it’s important to be vaccinated, even if you’ve already had Covid-19.

Translation. “We have no clue what’s going one, but get more vaxx shots, because $cience!”


20 posted on 05/21/2022 6:37:33 AM PDT by Flick Lives (The CDC. Brought to you by Pfizer)
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