Posted on 02/22/2023 12:52:42 PM PST by Twotone
Israeli scientists gave an artificial molecule they invented to 30 mice suffering from Alzheimer’s — and found that all of them recovered, regaining full cognitive abilities.
They stress that this was a small sample of mice and that human testing is far off, but believe the result indicates that within a decade, their synthetic molecule could be developed into a drug for treating the degenerative disease.
The peer-reviewed research, led by neuroscientists from Ben-Gurion University, was recently published in the journal Translational Neurodegeneration.
“We are taking a very different approach than efforts at Alzheimer’s medicines that we have seen so far,” Prof. Varda Shoshan-Barmatz, the lead author, told The Times of Israel. “Most are trying to address plaque that forms in the brain, but we are addressing dysfunction elsewhere. And we’re optimistic. Mice who had Alzheimer’s and received our molecule and then underwent tests had the same cognitive abilities as mice who’d never had Alzheimer’s.”
Interestingly, the molecule appears to have been effective without significantly reducing the amount of plaque, which she thinks indicates that scientists may have been overly fixated on the plaque.
(Excerpt) Read more at timesofisrael.com ...
Does it help with mice who are just kind of stupid?
Mouse finally remembers who moved his cheese.
https://freerepublic.com/focus/f-chat/4001488/posts
Well if it is a concern at this time you can try basil supplements.
A few observations:
All the good stuff is five or more years away.
Do I need a glass of water to wash my molecule down?
Flowers for Algernon
Good news.
Offer it NOW to a small number of people who sign a detailed consent form saying that this "new molecule" may not help them, and may kill them. There would be plenty of interest.
But what do the ‘Palestinian’ scientists say???
I think you'd have quite a few volunteers.
“30 June 2017”
“voltage-dependent anion channel 1 (VDAC1), the most abundant protein on the outer membrane of mitochondria. VDAC1 is the gatekeeper for the passages of metabolites, nucleotides, and ions; it plays a crucial role in regulating apoptosis”
https://www.frontiersin.org/articles/10.3389/fphys.2017.00460/full
I guess they got tired of curing cancer.
“28 December 2022”
“amyloid-beta (Aβ)-induced VDAC1 and p53 overexpression and apoptotic cell death were prevented by VBIT-4”
https://translationalneurodegeneration.biomedcentral.com/articles/10.1186/s40035-022-00329-7
“2016 Nov 25”
“Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction”
“compounds VBIT-3 and VBIT-4”
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122769/
The molecule prevents cellular death by binding to a protein, changing nothing, leaving the patient the cognitive ability to wonder,
“What’s the other shoe, and when does IT drop?”
Nice. /s
But they’ll be out of business once the rest of the research community pulls their collective head out - ahem - and stop suppressing prior valid research.
If this works, we can cut Medicare and Medicaid costs in half - it would save $500 billion a year in expenses.
Pinky: “Gee Brain, what are we gonna do tonight?”
Brain: “The same thing we do every night, try to take over the world!”
Mouse finally remembers to put on his pants before leaving the mousehole :)
Maybe this could fix Disney.
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