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Finding the Achilles' Heel of Cancer
American Friends Tel Aviv University ^ | December 10, 2009 | Unknown

Posted on 12/10/2009 10:58:44 AM PST by decimon

New TAU study finds stroke drug kills cancer cells and leaves normal cells intact

A never-approved drug developed to prevent the death of nerve cells after a stroke can efficiently kill cancer cells while keeping normal cells healthy and intact, an international team led by a Tel Aviv University researcher is reporting in the journal Breast Cancer Research.

Prof. Malka Cohen-Armon of TAU's Sackler School of Medicine found that the stroke drug — a member of a family of phenanthridine derivatives developed by an American drug company — worked to kill cancer in mice which had been implanted with human breast cancer cells.

"Not only did the drug kill the cancer, but when we investigated normal cells, we discovered that they'd reacted as though they hadn't come in contact with the drug," says Prof. Cohen-Armon. "This is the result we were hoping for. If human trials go well, we could have an entirely new class of drugs in our hands for the fight against cancer."

(Excerpt) Read more at aftau.org ...


TOPICS: Health/Medicine; Science
KEYWORDS: christianright; israel

1 posted on 12/10/2009 10:58:44 AM PST by decimon
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To: decimon

WOW! this could be seriesly Hugh!


2 posted on 12/10/2009 11:06:22 AM PST by stefanbatory (Weed out the RINOs! Sign the pledge. conservativepledge.org)
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To: decimon

Oh I hope this is true. I know women in dire straits from this horrible disease.


3 posted on 12/10/2009 11:10:29 AM PST by Aria ( "The US republic will endure until Congress discovers it can bribe the public with the people's $.")
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To: decimon

Though wonderful if true, the article seems to have failed to provide the name of this wondrous compound. Confidential? Secret stuff? Maybe there is no name for it, but it begs elaboration and specificity as to what the stuff is.

Could be the greatest thing since antibiotics, but whoever wrote this is so light on information that it’s virtually useless as an scientific announcement.


4 posted on 12/10/2009 11:10:38 AM PST by Habibi
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To: Habibi
...the article seems to have failed to provide the name of this wondrous compound.

The drug was never approved so it may not have had a name other than some tongue-twisting descriptive.

"...a member of a family of phenanthridine derivatives..."

5 posted on 12/10/2009 11:28:02 AM PST by decimon
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To: Aria

Don’t worry it has been peer reviewed.


6 posted on 12/10/2009 11:30:42 AM PST by pas
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To: decimon
Finding the Achilles' Heel of Cancer

Otto Warburg won the Nobel Prize in 1931 for his discovery that all cancer is anaerobic - it does not live on oxygen.

Sounds like an "Achilles heel" to me.

7 posted on 12/10/2009 11:32:26 AM PST by Talisker (When you find a turtle on top of a fence post, you can be damn sure it didn't get there on it's own.)
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To: Talisker
Otto Warburg won the Nobel Prize in 1931 for his discovery that all cancer is anaerobic - it does not live on oxygen.

Sounds like an "Achilles heel" to me.

Doesn't sound like anything to me. If cancer cells don't live on oxygen then what do they live on? Something we can deprive them of to kill them? Did Warburg cure cancer? What is your point?

8 posted on 12/10/2009 11:37:54 AM PST by decimon
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To: decimon
If cancer cells don't live on oxygen then what do they live on?

They use oxygen all right. The Achilles' heel of cancer is the cells' replication rate. Most cancer treatments are targeted on that already. The catch has always been in the collateral damage to normal cells, which this drug apparently avoids.

9 posted on 12/10/2009 12:01:59 PM PST by thulldud (It HAS happened here!)
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To: AdmSmith; Berosus; bigheadfred; Convert from ECUSA; dervish; Ernest_at_the_Beach; Fred Nerks; ...
can efficiently kill cancer cells while keeping normal cells healthy and intact, an international team led by a Tel Aviv University researcher is reporting
Thanks decimon.
10 posted on 12/10/2009 4:07:01 PM PST by SunkenCiv (https://secure.freerepublic.com/donate/__Since Jan 3, 2004__Profile updated Monday, January 12, 2009)
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To: Habibi; decimon; SunkenCiv
Though wonderful if true, the article seems to have failed to provide the name of this wondrous compound. Confidential? Secret stuff? Maybe there is no name for it, but it begs elaboration and specificity as to what the stuff is.

A selective eradication of human nonhereditary breast cancer cells by phenanthridine-derived polyADP-ribose polymerase inhibitors

If you go to Breast Cancer Research, it was the first article.

11 posted on 12/10/2009 9:45:08 PM PST by neverdem (Xin loi minh oi)
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To: decimon
Doesn't sound like anything to me. If cancer cells don't live on oxygen then what do they live on? Something we can deprive them of to kill them? Did Warburg cure cancer? What is your point?

Go read some biology before you post something this crude. Anaerobic metabolism is hardly uncommon - your muscles use it for short exertions, for example. And yeah, he "cured" cancer cells through "depriving" them of the anaerobic environment the require, by simply giving them oxygen. Unlike muscle cells, oxygen stops cancerous cells from being cancerous - ALL cancerous cells. That's called a "point." What's more, there are indications that a cancer cell is merely a normal cell that doesn't have enough oxygen. That's called another "point." Thes kind of points lead to investigations about metabolic oxygen levels and cancer responses, which in turn lead to medical intervention theories to be tested. That's called "science."

But hey, Nobel Prizes in medicine don't necessarily mean anything just because they exist. It's not like the Nobel committee saw any promise in Warburg's work. They just felt like giving him a prize, kinda like Obama's, right?

Sheesh.

12 posted on 12/15/2009 7:35:16 AM PST by Talisker (When you find a turtle on top of a fence post, you can be damn sure it didn't get there on it's own.)
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To: thulldud
They use oxygen all right.

No, they don't. That's why Warburg got the Nobel - for discovering this. If it's been refuted, post some citations. Otherwise, why not let a very important truth about cancer metabolism be heard?

13 posted on 12/15/2009 7:37:33 AM PST by Talisker (When you find a turtle on top of a fence post, you can be damn sure it didn't get there on it's own.)
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To: decimon

When obama care is passed, it won’t matter. All research will slow down and then stop.


14 posted on 12/15/2009 7:39:43 AM PST by sport
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