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Stem Cells Used To Reverse Paralysis In Animals
science daily ^ | 01.29.09

Posted on 01/31/2009 9:48:45 PM PST by Coleus

A new study has found that transplantation of stem cells from the lining of the spinal cord, called ependymal stem cells, reverses paralysis associated with spinal cord injuries in laboratory tests. The findings show that the population of these cells after spinal cord injury was greater than comparable cells from healthy animal subjects. The results open a new window on spinal cord regenerative strategies.

The transplanted cells were found to proliferate after spinal cord injury and were recruited by the specific injured area. When these cells were transplanted into animals with spinal cord injury, they regenerated ten times faster while in the transplant subject than similar cells derived from healthy control animals.

Spinal cord injury is a major cause of paralysis, and the trauma destroys numerous cell types, including the neurons that carry messages between the brain and the rest of the body. In many spinal injuries, the cord is not actually severed, and at least some of the signal-carrying nerve cells remain intact. However, the surviving nerve cells may no longer carry messages because oligodendrocytes, which comprise the insulating sheath of the spinal cord, are lost. The regenerative mechanism discovered was activated when a lesion formed in the injured area. After a lesion formed in the transplant subject, the stem cells were found to have a more effective ability to differentiate into oligodendrocytes and other cell types needed to restore neuronal function.

Currently, there are no effective therapies to reverse this disabling condition in humans. However, the presence of these stem cells in the adult human spinal cords suggests that stem cell-associated mechanisms might be exploited to repair human spinal cord injuries. Given the serious social and health problems presented by diseases and accidents that destroy neuronal function, there is an ever-increasing interest in determining whether adult stem cells

(Excerpt) Read more at sciencedaily.com ...


TOPICS: Health/Medicine; Science
KEYWORDS: adultstemcells; spinalcord

1 posted on 01/31/2009 9:48:45 PM PST by Coleus
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To: Coleus

So Christopher Reeves will walk again?


2 posted on 01/31/2009 10:20:52 PM PST by null and void (We are now in day 12 of our national holiday from reality.)
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To: null and void

Word is that there are several that have been paralyzed that are walking again (in varying stages)... the reason it is not HERALDED from every rooftop.. it was done with ADULT STEM CELLS from the same Individual, and not FETAL STEM CELLS.

Don’t believe in ghosts, so if I see Christopher Reeve Walking... you will see me ... RUNNING!!!


3 posted on 01/31/2009 10:32:40 PM PST by gwilhelm56 (MULLAH HUSSEIN - which part of "Congress shall make no Law" - do you NOT UNDERSTAND??)
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To: gwilhelm56
Don’t believe in ghosts, so if I see Christopher Reeve Walking... you will see me ... RUNNING!!!

Why? You don't believe in ghosts, remember?

Could it be...


4 posted on 01/31/2009 10:45:06 PM PST by null and void (We are now in day 12 of our national holiday from reality.)
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To: null and void

I saw those manipulated road signs...Too funny!!


5 posted on 02/01/2009 5:39:23 AM PST by Sacajaweau (I'm planting corn...Have to feed my car...)
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To: null and void

Those aren’t ZOMBIES...

THEY’re THE ... ACLU!!! RRRRRRUUUUUNNNNNNNN!!!!!!


6 posted on 02/01/2009 12:32:56 PM PST by gwilhelm56 (MULLAH HUSSEIN - which part of "Congress shall make no Law" - do you NOT UNDERSTAND??)
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