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How Broccoli Cuts Prostate Cancer Risk
The Times of India ^

Posted on 07/24/2010 8:11:21 PM PDT by nickcarraway

A new study has shed light on the interaction between broccoli consumption and reduced prostate cancer risk.

Researchers have found that sulforaphane, a chemical found in broccoli, interacts with cells lacking a gene called PTEN to reduce the chances of prostate cancer developing.

Richard Mithen, from the Institute of Food Research, an institute of BBSRC, worked with a team of researchers on Norwich Research Park, UK, to carry out a series of experiments in human prostate tissue and mouse models of prostate cancer to investigate the interactions between expression of the PTEN gene and the anti-cancer activity of sulforaphane.

"PTEN is a tumour suppressor gene, the deletion or inactivation of which can initiate prostate carcinogenesis, and enhance the probability of cancer progression. We’ve shown here that sulforaphane has different effects depending on whether the PTEN gene is present,” he said.

The research team found that in cells, which express PTEN, dietary intervention with SF has no effect on the development of cancer.

In cells that don’t express the gene, however, sulforaphane causes them to become less competitive, providing an explanation of how consuming broccoli can reduce the risk of prostate cancer incidence and progression.

"This also suggests potential therapeutic applications of sulforaphane and related compounds,” Mithen added.

The study appears in BioMed Central’s open access journal Molecular Cancer.


TOPICS: Education; Food; Health/Medicine
KEYWORDS: broccoli; cancer; health

1 posted on 07/24/2010 8:11:24 PM PDT by nickcarraway
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To: nickcarraway

hmmmmmm

THX THX.


2 posted on 07/24/2010 8:16:10 PM PDT by Quix (THE PLAN of the Bosses: http://www.freerepublic.com/focus/religion/2519352/posts?page=2#2)
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To: nickcarraway

3 posted on 07/24/2010 8:17:43 PM PDT by library user
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To: nickcarraway

Well, guess that explains my recent clear colonoscopy (when my aunt died of colon cancer)...I eat broccoli or broccoli slaw at least once a week.

So thankful that I LOVE it!!


4 posted on 07/24/2010 8:21:26 PM PDT by Reddy (B.O. stinks)
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To: nickcarraway

Dana Carvey - Choppin’ Broccoli

http://www.youtube.com/watch?v=WR6y71x3tSY


5 posted on 07/24/2010 8:21:52 PM PDT by dfwgator
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To: nickcarraway

Bump


6 posted on 07/24/2010 8:22:09 PM PDT by Man from Oz
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To: nickcarraway

Bump


7 posted on 07/24/2010 8:22:13 PM PDT by Man from Oz
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To: Reddy

PS... not that I would have a prostate! :)


8 posted on 07/24/2010 8:22:18 PM PDT by Reddy (B.O. stinks)
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To: Reddy
It helps even if you don't have a prostate: Broccoli may help fight breast cancer
9 posted on 07/24/2010 8:25:34 PM PDT by nickcarraway
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To: nickcarraway
I eat lots of broccoli and it didn't stop me from getting prostate cancer.

Lamh Foistenach Abu!
10 posted on 07/24/2010 8:27:17 PM PDT by ConorMacNessa (HM/2 USN, 3/5 Marines, RVN '69 - St. Michael the Archangel, defend us in battle!)
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To: ConorMacNessa

Well, hopefully it inhibited it’s growth. Hope you are doing well with that.


11 posted on 07/24/2010 8:28:32 PM PDT by nickcarraway
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To: nickcarraway
Are you supposed to eat the broccoli or what?
12 posted on 07/24/2010 8:28:50 PM PDT by kbennkc (For those who have fought for it freedom has a flavor the protected will never know .F Trp 8th Cav)
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To: kbennkc
Vile Weed!!!
13 posted on 07/24/2010 8:30:56 PM PDT by ExtremeUnction
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To: kbennkc
Vile Weed!!!
14 posted on 07/24/2010 8:31:00 PM PDT by ExtremeUnction
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To: kbennkc
Vile Weed!!!
15 posted on 07/24/2010 8:31:10 PM PDT by ExtremeUnction
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To: nickcarraway

Stir-fried chicken, broccoli and onions with stirfry sauce over brown rice is great.


16 posted on 07/24/2010 8:33:54 PM PDT by SeaHawkFan
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To: nickcarraway
Had radiation therapy two years ago - now cancer free. Still eating broccoli. :)

Lamh Foistenach Abu!
17 posted on 07/24/2010 8:34:47 PM PDT by ConorMacNessa (HM/2 USN, 3/5 Marines, RVN '69 - St. Michael the Archangel, defend us in battle!)
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To: ExtremeUnction

I like broccoli. It's....good...for...you.....

18 posted on 07/24/2010 8:36:55 PM PDT by WeatherGuy
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To: Reddy
Please elaborate on ‘broccoli slaw’...

I love plain ol’ slaw ( cabbage )....

Never had broccoli slaw...

19 posted on 07/24/2010 8:47:54 PM PDT by waterhill (i)
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To: nickcarraway

This might be more helpful

http://www.youtube.com/watch?v=W-jB9RDN-mE


20 posted on 07/24/2010 8:51:01 PM PDT by WKB (Oil spill = illegal immigration -- Until we stop the leak we will never fix the problems.)
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To: nickcarraway

Also found in cauliflower, brussel sprouts, cabbage, artichokes, and other related cruciferous vegetables.


21 posted on 07/24/2010 8:52:08 PM PDT by Fred Hayek (FUBO! I salute you with the soles of my shoes!)
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To: nickcarraway

Aw gee... do I have to give up my other prostate cleaning program?


22 posted on 07/24/2010 8:58:05 PM PDT by Ronin
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To: Ronin

Why not incorporate the two?


23 posted on 07/24/2010 8:58:58 PM PDT by nickcarraway
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To: ConorMacNessa

Congratulations on your health and glad you got it caught early. I am a 48 year old man who is dealing with fluctuating PSA readings. My urologist has been testing twice a year since I went through a biopsy 3 years ago.
Seems I am dealing with a recurrent infection that confounds my PSA results.

Early detection is the key (I keep telling myself that :) ) Having been blessed with genetics on both sides it will only be a matter of time before it eventually crops up.

It would be nice if something in the food that we eat can be a silver bullet for disease prevention but alas, your personal experience emphasizes that these foods are not a panacea for the body’s ills.


24 posted on 07/24/2010 9:00:26 PM PDT by Man from Oz
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To: nickcarraway

Since I already like brocolli and eat it a lot, I probably already have.

I guess my prostate is gonna live forever, but these hairy palms...


25 posted on 07/24/2010 9:01:06 PM PDT by Ronin
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To: nickcarraway

That end doesn’t eat, you know.


26 posted on 07/24/2010 9:07:42 PM PDT by RichInOC (No! BAD Rich! (What'd I say?))
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To: Man from Oz

PSA number are very unreliable.


27 posted on 07/24/2010 9:26:42 PM PDT by nickcarraway
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To: kbennkc

.

.

brocolli is good with chees sauce.

OT: By the way, Houston museum’s ‘corpe flower’ is blooming.
Live Cam:
http://www.hmnsmedia.org/CorpseFlower/

.


28 posted on 07/24/2010 10:16:26 PM PDT by patriot08 (TEXAS GAL- born and bred and proud of it!)
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To: nickcarraway; Man from Oz

Yes, PSA numbers can and do vary; however, if possible, use the same laboratory and ensure they are using the same standards and measurement methods each time. Likewise, PSA numbers, or more specifically, the velocity factor is an important number to know. If your PSA increases by .75 in one year, then it may well mean you need further testing and/or a biopsy. This applies even is your PSA is below 4.0 Ask for a “free PSA” test if your velocity factor jumps by .75 or more before you have a biopsy. Then decide. PC is nothing to mess around with. Been there, done that and still have the tee shirt.


29 posted on 07/24/2010 10:46:28 PM PDT by miele man
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To: miele man

I wouldn’t disagree with your advice, but I would say don’t freak out because you have a huge spike in PSA. I’ve seen too many cases where the numbers jump around in dramatic ways.


30 posted on 07/24/2010 10:55:38 PM PDT by nickcarraway
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To: ConorMacNessa
I have ate it all my life and I still got prostate cancer and so did my Brother.
I hate stuff like this, it is like the lycopene study that found it could prevent cancer, the only problem is that you would have had to eat something like 20 pounds of tomatoes a day to get the same results they saw in mice. (By the way the crooks that sell One-A-Day vitamins still advertise it being in their tablets) Taken from a scientific view this is harmless, but I believe that in many cases people use news like this to delay regular Doctor checkups that can really save your life.
The other thing about these news generating studies is that many of these results are released for the purpose of getting Federal Research money, like the red meat causes colon cancer study. That study is ran by a militant vegetarian uses worse science than the global warming bunch does. And her funding is up next year so look for the Red Meat Causes Colon Cancer headline to return around April 2011.

If you want to read more about this see the link below

http://www.foxnews.com/story/0,2933,307458,00.html

31 posted on 07/24/2010 11:57:25 PM PDT by Wooly
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To: Wooly

If you have the time to read this article, you will never again be tricked into fearing something or false hope which can kill you.

http://www.junkscience.com/news/sws/sws-chapter1.html


32 posted on 07/25/2010 12:02:41 AM PDT by Wooly
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To: nickcarraway

I love any kind of soup. Trim off those big stalks. Simmer the broccoli florets in chicken stock, cream, butter, salt, etc. Puree half. There are plenty of good recipes on the net.

Or get it already made. I get this and thin it up a little with milk. My mouth waters just thinking about a big bowl of soup.

33 posted on 07/25/2010 12:32:06 AM PDT by Daaave ( "Was blind, but now I see.")
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To: ConorMacNessa

me neither. Maybe we didn’t eat enough?

Wonder if it will help against a recurrence?


34 posted on 07/25/2010 7:12:36 AM PDT by wildbill (You're just jealous because the Voices talk only to me.)
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To: wildbill
It's my wife's favorite veggie - we seem to eat it incessantly.

Lamh Foistenach Abu!
35 posted on 07/25/2010 7:21:50 AM PDT by ConorMacNessa (HM/2 USN, 3/5 Marines, RVN '69 - St. Michael the Archangel, defend us in battle!)
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To: Man from Oz

Google Modified Citrus Pectin and Graviola.


36 posted on 07/25/2010 7:37:52 AM PDT by csmusaret (A government that can dictate how much water flows into a toilet is a powerful government indeed.)
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To: nickcarraway

Yes, PSA “spikes” happen for various reasons and not all are harbingers of PC but I’d say you and I disagree about the PSA spikes and what they mean. In some instances, it could mean. for example, a guy could have engaged in sexual relations the night before his PSA test which means a guaranteed “spike” in PSA. In other instances, there truly is something going on which signals a significant change and needs to be checked further, either with a digital exam and/or a biopsy. You can also choose to wait and have a re-test.

If a guy or his doc is reticent to trust PSAs, then how do you propose a potential cancer be found?


37 posted on 07/25/2010 7:50:46 AM PDT by miele man
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To: waterhill

WM and other stores sell chopped broccoli prepackaged in a bag in the produce aisle....

Chop up noodles from one pkg of oriental ramen.... lightly brown in a T of butter. Set aside. Make a sauce of oriental ramen spice package, 1/4 cup olive oil, 2 T sugar, 1 T red wine vinegar. Mix browned noodles, 1/2 cup chopped pecans, chopped broccoli, 1/4 c chopped green onions and sauce that you mixed. I also add craisins or raisins.

So easy and sooo good!

Or, you could just mix the broccoli cuts with plain, old-fashioned slaw dressing!


38 posted on 07/25/2010 7:02:07 PM PDT by Reddy (B.O. stinks)
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