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'Universal' cancer vaccine developed
The Telegraph ^ | April 8, 2012 | Richard Gray

Posted on 04/08/2012 2:58:22 PM PDT by Free ThinkerNY

A vaccine that can train cancer patients' own bodies to seek out and destroy tumour cells has been developed by scientists.

The therapy, which targets a molecule found in 90 per cent of all cancers, could provide a universal injection that allows patients' immune systems to fight off common cancers including breast and prostate cancer.

Preliminary results from early clinical trials have shown the vaccine can trigger an immune response in patients and reduce levels of disease.

The scientists behind the vaccine now hope to conduct larger trials in patients to prove it can be effective against a range of different cancers.

They believe it could be used to combat small tumours if they are detected early enough or to help prevent the return and spread of disease in patients who have undergone other forms of treatment such as surgery.

Cancer cells usually evade patient's immune systems because they are not recognised as being a threat. While the immune system usually attacks foreign cells such as bacteria, tumours are formed of the patient's own cells that have malfunctioned.

Scientists have, however, found that a molecule called MUC1, which is found in high amounts on the surface of cancer cells, can be used to help the immune system detect tumours.

The new vaccine, developed by drug company Vaxil Biotheraputics along with researchers at Tel Aviv University, uses a small section of the molecule to prime the immune system so that it can identify and destroy cancer cells.

(Excerpt) Read more at telegraph.co.uk ...


TOPICS: Health/Medicine; Science
KEYWORDS: cancer; cancervaccine; developed; israel; isrealcancerresearch; muc1; telaviv; universal; vaccine; vaxil
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1 posted on 04/08/2012 2:58:26 PM PDT by Free ThinkerNY
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To: Free ThinkerNY
Yeah, but what about something really important like banishing cellulite or male/female pattern baldness.

Just kidding, this sounds great! Hope it works!

2 posted on 04/08/2012 3:07:30 PM PDT by RoosterRedux
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To: Free ThinkerNY

Like the latest IPhone, I think Ill wait till the bugs are worked out. I would hate for it to target the wrong cells, and then find out they had released an update I had missed.


3 posted on 04/08/2012 3:08:17 PM PDT by DainBramage
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To: Free ThinkerNY
The new vaccine, developed by drug company Vaxil Biotheraputics along with researchers at Tel Aviv University

Long live Israel.

4 posted on 04/08/2012 3:09:50 PM PDT by Semper911 (When you want to rob Peter to pay Paul, you'll always have the support of Paul.)
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To: Free ThinkerNY

Isn’t this how most zombie movies start?


5 posted on 04/08/2012 3:09:55 PM PDT by driftdiver (I could eat it raw, but why do that when I have a fire.)
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To: driftdiver

6 posted on 04/08/2012 3:17:17 PM PDT by rjsimmon (1-20-2013 The Tree of Liberty Thirsts)
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To: Free ThinkerNY

It’s ironic/sad to read this. Some years back my sister lost her battle with breast cancer. She really wanted to live and went through EVERYTHING. The most extreme chemo, extreme radiation and surgeries possible. All for naught.

When she went to the hospital for what would be the last time, I remember the family standing around talking to her doctor. He was really a great guy. We all asked him if there was anything he could do. This story really brought back memories of his answer, “I’m sorry, we’ve done everything we can, there’s nothing left to try. And I hate to tell you this, but we really can’t stop this stuff from the outside anyway. It’s sad, because our own bodies could easily get rid of cancer. If our body could just be convinced cancer was something that didn’t belong there, it could be gone a month.”


7 posted on 04/08/2012 3:18:52 PM PDT by I cannot think of a name
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To: Free ThinkerNY

How does this help the DNC divide the nation?

US news will not carry this great, awesome story.


8 posted on 04/08/2012 3:21:29 PM PDT by NoLibZone (Anybody but Obama, because it's not always about me. Thank God McCain/Palin lost! - Right?)
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To: driftdiver

ha!

Exactly what I was thinking.


9 posted on 04/08/2012 3:22:01 PM PDT by mamelukesabre (Hello, I'm a TAGLINE virus. Please help me spread by copying me into YOUR tag line)
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To: Free ThinkerNY
We've been reading about such things for years but the articles always end with the line “much more study is needed”. Then after boat loads of money is thrown at it, we hear very little else. Are these guys truly willing to release any successful treatment that makes chemo treatment obsolete or less proffitable?
10 posted on 04/08/2012 3:29:19 PM PDT by excalibur21
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To: DainBramage

“I think Ill wait till the bugs are worked out.”

If one is terminal, why worry about working out the bugs? I think it should be marketed right away for such patients.


11 posted on 04/08/2012 3:31:31 PM PDT by Dr. Bogus Pachysandra ( Ya can't pick up a turd by the clean end!)
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To: I cannot think of a name

I’m truly sorry for your loss.

Hopefully, this new treatment will be of help if any of your other loved ones falls ill to the disease.


12 posted on 04/08/2012 3:32:48 PM PDT by basil (It's time to rid the country of "gun free zones" aka "Killing Fields")
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To: Dr. Bogus Pachysandra

Surely for them but not for me as a vaccine.


13 posted on 04/08/2012 3:36:32 PM PDT by DainBramage
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To: Semper911
Long live Israel.

Just what I was thinking.

"I will make you into a great nation. I will bless you and make you famous, and you will be a blessing to others." Gen 12:2

14 posted on 04/08/2012 3:46:33 PM PDT by presently no screen name
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To: DainBramage

“Surely for them but not for me as a vaccine.”

Yes.


15 posted on 04/08/2012 3:52:33 PM PDT by Dr. Bogus Pachysandra ( Ya can't pick up a turd by the clean end!)
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To: excalibur21

If ObamaCare stands...I think we will see a lot more of this.

Cancer treatment is very expensive. Not at all in line with the criteria.


16 posted on 04/08/2012 3:56:37 PM PDT by berdie
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To: Free ThinkerNY

Cancer is a absolute destroyer of life and I truly pray and hope this is true.


17 posted on 04/08/2012 3:56:37 PM PDT by JamesA (You don't have to be big to stand tall)
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To: Free ThinkerNY
The therapy... could provide a universal injection...

A universal, mandatory injection, no doubt.

What could go wrong?

18 posted on 04/08/2012 4:06:51 PM PDT by Talisker (He who commands, must obey.)
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To: rjsimmon
I liked this one better.


19 posted on 04/08/2012 4:20:35 PM PDT by FReepaholic (Stupidity is not a crime, so you're free to go.)
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To: Free ThinkerNY

They also have wonderful progress on curing diabetes from Israel as well. What did we get from the other side of the family? Oh yea, zeros. We’re adding a few more to the national debt this month...


20 posted on 04/08/2012 4:22:07 PM PDT by Dogbert41 ("...or by Jerusalem, for it is the city of the Great King. " -Jesus)
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To: basil

I was diagnosed with lung cancer last week and have surgery next week. My wwife had uterine and breast — double mastectomy 5 yrs. ago - thought we were OK, but her markers just went up. PET scan tomorrow.

Cancer is an evil bitch!!


21 posted on 04/08/2012 4:22:22 PM PDT by rickyc
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To: I cannot think of a name

I’m very sorry for your loss.

I lost a sister Jan 1, 2011


22 posted on 04/08/2012 4:23:38 PM PDT by TASMANIANRED (We kneel to no prince but the Prince of Peace)
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To: rickyc

Prayers lifted for you and your wife.

May God’s hand be one with your surgeons.


23 posted on 04/08/2012 4:25:37 PM PDT by TASMANIANRED (We kneel to no prince but the Prince of Peace)
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To: rickyc

You need a prayer thread...

I ask for your permission?


24 posted on 04/08/2012 4:27:06 PM PDT by TASMANIANRED (We kneel to no prince but the Prince of Peace)
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To: FReepaholic
Good choice.  One of my all-time favorite movies.  You could see where movies such as "night of the Living Dead" got their inspiration from.
25 posted on 04/08/2012 4:28:50 PM PDT by softwarecreator
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To: rickyc

Prayers offered for you and your wife.


26 posted on 04/08/2012 4:29:23 PM PDT by FourPeas ("Maladjusted and wigging out is no way to go through life, son." -hg)
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To: I cannot think of a name
It’s sad, because our own bodies could easily get rid of cancer. If our body could just be convinced cancer was something that didn’t belong there, it could be gone a month.”

Unfortunaely I have been around and will continue to be around a lot of cancer specialists. Surgeons radiologists you name it.

One time I asked a surgeon who was removing a melanoma from my back about so-called miracle cures; where a person is diagnosed by several top cancer doctors as having less than a year to live, but somehow manages to live much longer and basically becomes cancer free. He told me what happens is the patients immune system, for whatever reason starts to target the cancer cells and eventually eliminates them.

So getting the immune system to fight cancer is the way to cure it. -Tom

27 posted on 04/08/2012 4:30:46 PM PDT by Capt. Tom
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To: rickyc
Prayers up for you and your wife.
28 posted on 04/08/2012 4:49:43 PM PDT by grey_whiskers (The opinions are solely those of the author and are subject to change without notice.)
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To: Free ThinkerNY

I am sure it will be banned under Obama Deathcare !


29 posted on 04/08/2012 4:51:44 PM PDT by CORedneck
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To: presently no screen name
Thank God for Israel. It is beyond me why people curse Israel and then bring upon themselves to be cursed. Up my bloodline, there was a Jewish Rabbi but unfortunately, it i not enough to give me Israeli citizenship.

Long live Israel.

Just what I was thinking.

"I will make you into a great nation. I will bless you and make you famous, and you will be a blessing to others." Gen 12:2
30 posted on 04/08/2012 4:57:27 PM PDT by CORedneck
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To: excalibur21
"We've been reading about such things for years but the articles always end with the line “much more study is needed”. Then after boat loads of money is thrown at it, we hear very little else. Are these guys truly willing to release any successful treatment that makes chemo treatment obsolete or less profitable?"

My guess is, no they wont. When my wife was diagnosed in 08, she went through an extensive chemo regimen and later radiation. I found out that this treatment plan has been SOP for the last 30 years.

You keep hearing about progress, but never see any of it in practice. Coincidence?

31 posted on 04/08/2012 5:08:42 PM PDT by ArchAngel1983 (Arch Angel- on guard / Wenn Sie etwas sehen, sagen Sie etwas!)
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To: T Minus Four

ping


32 posted on 04/08/2012 5:19:16 PM PDT by 4mer Liberal
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To: rickyc
I was diagnosed with lung cancer last week and have surgery next week. My wwife had uterine and breast — double mastectomy 5 yrs. ago - thought we were OK, but her markers just went up. PET scan tomorrow. Cancer is an evil bitch!!

Fight! With everything you have!

My family has lost a few members due to this insidiousness, there have been several successful battles.

Never give up the fight!

33 posted on 04/08/2012 5:19:29 PM PDT by Focault's Pendulum (If Obama was any more thin skinned, he'd have a receptacle end: Dennis Miller)
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To: T Minus Four

ping


34 posted on 04/08/2012 5:19:53 PM PDT by 4mer Liberal
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To: rickyc

It certainly is that!

I will keep you in my prayers.....


35 posted on 04/08/2012 5:28:21 PM PDT by basil (It's time to rid the country of "gun free zones" aka "Killing Fields")
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To: FReepaholic
i liked the remake better

36 posted on 04/08/2012 5:36:56 PM PDT by Chode (American Hedonist - *DTOM* -ww- NO Pity for the LAZY)
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To: Free ThinkerNY

Just about every year I read an article about a new cancer cure all drug.

It’s like Obama and socialism, this time it will work!


37 posted on 04/08/2012 5:39:31 PM PDT by Bubba_Leroy (The Obamanation Continues)
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To: Free ThinkerNY

There is also the risk of this causing a host of auto-immune disorders.


38 posted on 04/08/2012 5:39:42 PM PDT by tbw2
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To: rickyc

Prayers for both you and your wife. Keep up the good fight and have the utmost faith that you’ll be well. Just believe. You can do this and so can your dear wife. Never never give up. (I just beat colon cancer and went back to work last week.)


39 posted on 04/08/2012 5:42:34 PM PDT by hershey
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To: FReepaholic
I liked this one better.

I just watched this on Netfix, what a pantload....
40 posted on 04/08/2012 5:43:38 PM PDT by WackySam (Obama got Osama just like Nixon landed on the moon.)
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To: Free ThinkerNY

Chavez is thrilled.


41 posted on 04/08/2012 5:45:38 PM PDT by TribalPrincess2U (Anyone not wanting an ID or purple thumb to vote isn't worthy of voting privilege.)
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Click


42 posted on 04/08/2012 5:45:53 PM PDT by RedMDer (https://support.woundedwarriorproject.org/default.aspx?tsid=93)
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To: excalibur21
We've been reading about such things for years but the articles always end with the line “much more study is needed”. Then after boat loads of money is thrown at it, we hear very little else. Are these guys truly willing to release any successful treatment that makes chemo treatment obsolete or less proffitable?

That's because these press releases are intended to raise money for technologies that have almost no hope of success. The company that makes this vaccine just did a reverse merger into a penny stock on the Tel Aviv stock exchange, which isn't a good sign.

If this vaccine had any hope they could have done a real IPO, been bought out by a larger company or received funding from a larger company which is common in biotech.

43 posted on 04/08/2012 5:51:36 PM PDT by Moonman62 (The US has become a government with a country, rather than a country with a government.)
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To: Capt. Tom

My last brush with cancer was via a beloved pet Lab I had treated, he did very well, happy as a clam until the day he died of unrelated causes.

During the course of going down to NC State, etc. for treatment, I had many conversations with both veterinary oncologists as well as other people having their pets treated.

The reason I mention this, is that there was at that time an extensive trial going on for a melanoma vaccine that apparently was proving not just effective for melanoma in dogs, but also for “off label” use with other cancers.

Veterinary trials in dogs are where just about every human cancer treatment we have began. Dogs and humans are affected by cancers very similarly, and respond to treatments very similarly as well.

I would inquire about this melanoma vaccine, if I were to find myself in such a position. This was in 2007.


44 posted on 04/08/2012 5:52:06 PM PDT by RegulatorCountry
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To: Free ThinkerNY

Great. I hope they will let the public use it if it works.


45 posted on 04/08/2012 6:07:02 PM PDT by freekitty (Give me back my conservative vote; then find me a real conservative to vote for)
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To: RegulatorCountry
Veterinary trials in dogs are where just about every human cancer treatment we have began. Dogs and humans are affected by cancers very similarly, and respond to treatments very similarly as well.

A major problem with cancer is there are so many different kinds;and we use only one word to describe it.
A word like Polio describes well a problem some of us humans have had to cope with, and a vaccine for polio will work on just about everyone because it is a specific problem. there are not dozens of diferent types of Polios like ther are dozens of different types of cancers.

Cancers are many types and the best cure would be to get the person's immune system to go after the cancer cells and rid them from the body. So far that hasn't happened.
So we are into elaborate treatment and no real cures for the many cancers we face.
There a thousands of cancer patients who would be willing to try these new treatments. Many of them have, and are doing it daily, but there are no real solutions yet.I am sure some, as a last resort, have tried drugs that seemed to have worked on dogs. -tom

46 posted on 04/08/2012 6:32:27 PM PDT by Capt. Tom
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To: Bubba_Leroy

“Just about every year I read an article about a new cancer cure all drug.”

It’s like net positive fusion energy - these miracles have been 10-15 years away for the last fifty years.

Seriously, this type of approach seems to be very promising, as long as it doesn’t make “a mistake”, and trigger really, really nasty autoimmune illnesses. Once you turn that system “on”, it’s really, really difficult to stop.


47 posted on 04/08/2012 7:10:03 PM PDT by The Antiyuppie ("When small men cast long shadows, then it is very late in the day.")
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To: tbw2

This is another really interesting approach:

http://www.viewzone.com/nakedrats.html

(No, this link will not take you to naked Democrats.)

These nasty little buggers have an amazing resistance to cancer and the reason is now apparently known.

Looks like they got something in return for being fairly disgusting creatures:).


48 posted on 04/08/2012 7:16:11 PM PDT by The Antiyuppie ("When small men cast long shadows, then it is very late in the day.")
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To: Free ThinkerNY

According to my 1st semester pharmacy notes, if a drug makes it this far it has about a 1 in 5 chance of making it to market. Sure hope it beats the odds.


49 posted on 04/08/2012 7:40:57 PM PDT by Slings and Arrows (You can't have Ingsoc without an Emmanuel Goldstein.)
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To: Capt. Tom
I was responding purely on the basis of your mentioning melanoma.

The melanoma vaccine that I mentioned being in clinical trial in 2007 has gone on to receive USDA approval in 2010 and is in fact the only cancer vaccine for either animal or human to have done so. The name of it is Oncept, from Merial.

It's widely regarded as a promising step toward a human melanoma vaccine, following the veterinary canine to human medical pathway of so many cancer treatments.

Here is a more layman oriented blog discussion of this:

http://blog.targethealth.com/?p=17888

And, here is a more scholarly clinical PDF:

http://www.elsevierscitech.com/pdfs/molonc0910/1_Newerainmetastaticmelanoma.pdf

A vaccine *is* immunomodulation. The therapy in humans appears to be aided by a number of other therapies, such as anti-angiogenic treatments.

I would watch this closely if melanoma is an issue or even something to which one might be prone due to heredity.

50 posted on 04/08/2012 7:54:52 PM PDT by RegulatorCountry
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