Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Hopeful News: The Cancer Moonshot May Have Just Taken Off Thanks to a Light-Activated 'Trojan Horse' Miracle Drug
PJ Media ^ | 06/04/2021 | Stacey Lennox

Posted on 06/04/2021 8:04:12 AM PDT by SeekAndFind

Scottish researchers at the University of Edinburgh have tested a “Trojan Horse” drug that can kill cancer cells and bacterial cells without damaging nearby tissues. Because cancer cells need to consume high amounts of food for energy to continue to reproduce, these researchers decided to target their eating habits, with very encouraging results:

Scientists at the University of Edinburgh combined the tiny cancer-killing molecule SeNBD with a chemical food compound to trick malignant cells into ingesting it.

The peer-reviewed experimental study was carried out on zebrafish and human cells, but researchers say more studies are needed to confirm if it is a safe and swift method of treating early stage cancer and drug-resistant bacteria.

The team combined a tiny cancer-killing molecule SeNBD and a chemical food compound that the insatiable cancer cells enjoy, creating a “metabolic warhead.” The combination prevents the cancer cells from identifying the threat and readily ingesting the SeNBD that seeks to destroy them in studies done to date. The deadly molecule is also a light-activated photosensitizer. This quality means it goes to work when a surgeon quite literally turns it on. Pretty ironic, given the media freak-out when President Trump posited that UV light might be a treatment for some illnesses.

The light-activated nature of the molecule may allow for unparalleled precision in treating tumors. It will permit surgeons to precisely place the poisoned food in the area where the cancer cells exist and activate them to work in the cancer cells they light up. Any of the medication that migrates into nearby tissues will not be activated, reducing the therapy’s impact on healthy cells.

(Excerpt) Read more at pjmedia.com ...


TOPICS: Health/Medicine; Science; Society
KEYWORDS: cancer; miracledrug

1 posted on 06/04/2021 8:04:12 AM PDT by SeekAndFind
[ Post Reply | Private Reply | View Replies]

To: SeekAndFind

Here’s a description of how this drug works from the DAILY MAIL via MSN:

https://www.msn.com/en-us/health/medical/successful-test-of-cancer-killing-trojan-horse%C2%B4-drug-marks/ar-AAKzuI1

Lead researcher Professor Marc Vendrell, chair of translational chemistry and Biomedical Imaging at the University of Edinburgh, said: “This research represents an important advance in the design of new therapies that can be simply activated by light irradiation, which is generally very safe.

“SeNBD is one of the smallest photosensitisers ever made and its use as a ‘Trojan horse’ opens many new opportunities in interventional medicine for killing harmful cells without affecting surrounding healthy tissue.”

According to Dr Sam Benson, a post-doctoral researcher at the university, “The mechanism of the drug’s delivery means it is delivered through the “front door of the cell” rather than having to “find a way to batter through the cell’s defenses”.

This technology could be an unparalleled miracle for cancer patients. Not only is a cancer diagnosis one that can devastate families, but the treatment is also often a terrible physical and psychological burden. Because many forms of chemotherapy and radiation target the body’s cells during specific points in the reproductive process, they can cause significant side effects. Their effects are not limited only to the cancer cells. They can also affect other cells in the body at the same point in the cellular reproductive process.

The current treatments are non-specific, resulting in nausea, vomiting and other forms of gastrointestinal problems, hair loss, and skin problems. Having supported more than one friend fighting for her health as she selected the wig she would wear to cover her now baby-fine hair, and held more than one basin while a cancer patient suffered from intractable vomiting, the idea of a drug without these side effects is a more than a blessing. It would also eliminate the need to pile on more drugs to treat these symptoms in an already weakened body.

The application to cancers that patients view as a death sentence, such as pancreatic, some types of brain, liver, and certain leukemias, could give hope to millions in the future. It does not appear from the studies that the treatment would be limited to certain types of cancer, as many forms of chemotherapy are. It simply capitalizes on the fact that all cancer cells are ravenous.

This technology may also have the added benefit of treating drug-resistant bacteria. The resistance of some strains of bacteria to available antibiotics is one of the perplexing challenges in treating infectious diseases. Tuberculosis and staphylococcus both have drug-resistant strains that lead to severe illness and death. That SeNBD as a Trojan Horse may treat these as well makes it a double miracle.

That this treatment has been successful in cellular studies is a significant breakthrough.


2 posted on 06/04/2021 8:06:39 AM PDT by SeekAndFind
[ Post Reply | Private Reply | To 1 | View Replies]

To: Ezekiel

3 posted on 06/04/2021 8:13:39 AM PDT by Daffynition (*Mega Dittoes and Mega Prayers* & :))
[ Post Reply | Private Reply | To 2 | View Replies]

To: SeekAndFind
This concept was a big deal, fanfare, newspapers, breathless reporting in 1985.

Most all cancer chemotherapy works on the fact that rapidly replicating cells are more sensitive to poisons than slow growing cells. Hence why you lose your hair and the lining of your gut during "chemo".

So OK there is a chemical that can be concentrated in the bad cells and when you shine a light it detonates.

Good luck with that - its been tried many times maybe this one will work.

4 posted on 06/04/2021 8:22:28 AM PDT by corkoman
[ Post Reply | Private Reply | To 2 | View Replies]

To: SeekAndFind

How many times have we heard “Cancer Breakthrough”. BS.
The governments of the world do not want a cancer cure. Cancer mainly hits older adults. They die, no more SS payments. No more medicare payments. They want us to contribute to SS all our working lives, then retire and die ASAP.


5 posted on 06/04/2021 8:32:20 AM PDT by lombardwarrior2
[ Post Reply | Private Reply | To 2 | View Replies]

To: SeekAndFind

My wife has had her third clear scan. On Tuesday she goes in for a relatively new blood test. This test compares the genetic profile of her tumor with a current blood sample. If there are no “matches” in the sample…she will be deemed “cured.”

Cancer is not a “single” thing that can be covered by “blanket cures.” But the treatments are amazing. Talk to anyone who has recently gone through the process. Its “Buck Rogers” stuff.


6 posted on 06/04/2021 8:36:40 AM PDT by Vermont Lt
[ Post Reply | Private Reply | To 1 | View Replies]

To: lombardwarrior2

That has to win the award as the dumbest thing I’ve read this morning.


7 posted on 06/04/2021 8:37:24 AM PDT by Vermont Lt
[ Post Reply | Private Reply | To 5 | View Replies]

To: Vermont Lt

I wish her the very best of outcomes.


8 posted on 06/04/2021 8:40:34 AM PDT by SueRae (An administration like no other.)
[ Post Reply | Private Reply | To 6 | View Replies]

To: Vermont Lt

My wife has had her third clear scan.

............

Those of us who go through the regular burden of scanxiety rejoice with you and wish you many clean scans ahead.


9 posted on 06/04/2021 9:22:15 AM PDT by lurk ( )
[ Post Reply | Private Reply | To 6 | View Replies]

To: SeekAndFind

This needs more testing but not so with the vax.


10 posted on 06/04/2021 9:29:30 AM PDT by bgill
[ Post Reply | Private Reply | To 1 | View Replies]

To: bgill

RE: This needs more testing

Since they have not declared any form of cancer a pandemic ( even though it kills more people than Covid-19 ), this WILL take years before it will be approved. There will be no EUA for this drug.


11 posted on 06/04/2021 9:33:44 AM PDT by SeekAndFind
[ Post Reply | Private Reply | To 10 | View Replies]

To: Vermont Lt
That has to win the award as the dumbest thing I’ve read this morning.


12 posted on 06/04/2021 9:51:39 AM PDT by libh8er
[ Post Reply | Private Reply | To 7 | View Replies]

To: Vermont Lt

One or more Eyores always rush to crap on any report of a promising cancer treatment.


13 posted on 06/04/2021 10:10:19 AM PDT by Magic Fingers (Political correctness mutates in order to remain virulent.)
[ Post Reply | Private Reply | To 7 | View Replies]

To: lombardwarrior2
"The governments of the world do not want a cancer cure. Cancer mainly hits older adults."

I dunno ... those same governments seem to be run by some real geezers.

14 posted on 06/04/2021 10:15:24 AM PDT by The Duke (Search for 'Sydney Ducks' and understand what is needed.)
[ Post Reply | Private Reply | To 5 | View Replies]

To: SeekAndFind

How far can light travel through healthy tissue until it hits cancerous tissues?


15 posted on 06/04/2021 10:52:46 AM PDT by House Atreides
[ Post Reply | Private Reply | To 1 | View Replies]

To: Vermont Lt

I have to agree with #5. Look what Cuomo did to New York during the CV-19 pandemic. Working out the numbers he is saving New York Billions of dollars. Other Governors are complicit also


16 posted on 06/04/2021 12:18:46 PM PDT by dirtymac ( Now Is The Time For All Good Men To ComeTo The Aid Of Their Country! NOW)
[ Post Reply | Private Reply | To 7 | View Replies]

To: Vermont Lt

I have to agree with #5. Look what Cuomo did to New York during the CV-19 pandemic. Working out the numbers he is saving New York Billions of dollars. Other Governors are complicit also


17 posted on 06/04/2021 12:19:19 PM PDT by dirtymac ( Now Is The Time For All Good Men To ComeTo The Aid Of Their Country! NOW)
[ Post Reply | Private Reply | To 7 | View Replies]

To: Vermont Lt

You must have missed this one by the bartender savant:
https://freerepublic.com/focus/f-news/3964850/posts


18 posted on 06/04/2021 12:21:54 PM PDT by newnhdad (Our new motto: USA, it was fun while it lasted.)
[ Post Reply | Private Reply | To 7 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson