Magnesium is essential for the immune system, including in the fight against cancer (“T cells can eliminate abnormal or infected cells efficiently only in a magnesium-rich environment”)

Medical Xpress / University of Basel / Cell ^ | Jan. 20, 2022 | Christoph Hess et al

[ConservativeMind]

The level of magnesium in the blood is an important factor in the immune system's ability to tackle pathogens and cancer cells. Researchers from have reported that T cells need a sufficient quantity of magnesium in order to operate efficiently. Their findings may have important implications for cancer patients.

Magnesium deficiency is associated with a variety of diseases, such as infections and cancer. Previous studies have shown that cancerous growths spread faster in the bodies of mice when the animals received a low-magnesium diet—and that their defense against flu viruses was also impaired. However, there has so far been little research into how exactly this mineral affects the immune system.

Now, researchers have discovered that T cells can eliminate abnormal or infected cells efficiently only in a magnesium-rich environment. Specifically, magnesium is important for the function of a T cell surface protein called LFA-1.

LFA-1 acts as a docking site, which plays a key role in the activation of T cells. "However, in the inactive state this docking site is in a bent conformation and thus cannot efficiently bind to infected or abnormal cells," Christoph Hess explains. "This is where magnesium comes into play. If magnesium is present in sufficient quantities in the vicinity of the T cells, it binds to LFA-1 and ensures that it remains in an extended—and therefore active—position.

The fact that magnesium is essential for the functioning of T cells may be a highly significant finding for modern cancer immunotherapies. These therapies aim to mobilize the immune system—in particular cytotoxic T cells—to fight cancer cells.

Using data from previously completed studies of cancer patients, the researchers were able to show that immunotherapies were less effective in patients with insufficient levels of magnesium in their blood.

[ConservativeMind]

Folks, this is a cheap mineral to supplement. Consider forms other than Magnesium Oxide and Magnesium Citrate to minimize bowel discomfort, though.

[ConservativeMind]

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[laplata]

Thanks for that. I take Magnesium Citrate in powder form because after some research, it is the most effective. So far, no bowel discomfort.

[Magnum44]

You think magnesium is important? Well...

[Pollard]

1. Wheat bran
2. Spinach, cooked
3. Swiss chard, cooked
4. Dark chocolate
5. Sunflower seeds, dried
6. Cashews
7. Mackerel
8. Flaxseeds
9. Almonds/almond butter
10. Pumpkin seeds, dried
11. Amaranth
12. Buckwheat groats/kasha
13. Black bean
14. Avocado
15. Quinoa
16. Spirulina
17. Figs, dried
18. Yogurt or kefir
19. Mung beans
20. Banana

[Lopeover]

Are these magnesium rich foods?

[NWFree]

I like super magnesium myself 👍🏻

[Pollard]

of course

[Seruzawa]

Taking magnesium may cause loose bowels at first but this goes away after a few days. Magnesium is an excellent remedy for many types of muscle aches and especially charlie horses. We use a brand called Calm regularly.

[Tea Party Terrorist]

I had night pains in my entire right leg, like cramps. They stopped 2 days after starting 400MG of Magnesium daily.

[Veto!]

Do they say how much magnesium you need? I take liquid calcium/magnesium every night, one tablespoon. It has 300 mg magnesium. I’m a very small person, so I’m sure that’s enough.

Also eat some, but not all of the natural sources listed on this thread.

[Veto!]

Amount you need daily from Web MD. My doctor checks this site to see which supplements he’ll prescribe for me. He prescribes calcium and magnesium.

https://www.webmd.com/diet/supplement-guide-magnesium#091e9c5e801b5705-1-4

[JimRed]

What is the recommended dosage for magnesium?

[ProtectOurFreedom]

“Food First” is the right approach. Here are the top foods for magnesium. Magnesium deficiency is very rare and supplements are rarely needed.

Note the nonsense in #3: “Shredded wheat (plain, unfrosted).” UNFROSTED?? Are they nuts?

1. Nuts and seeds
Almonds (roasted): 1 ounce = 80 milligrams of magnesium (20% of the recommended dietary allowance).
Cashews (roasted): 1 ounce = 72 milligrams of magnesium (18% RDA).
Flaxseed (whole): 1 tablespoon = 40 milligrams of magnesium (10% RDA).
Peanuts (dry roasted): 1 ounce = 49 milligrams of magnesium (12% RDA).
Pumpkin seeds (hulled, roasted): 1 ounce = 150 milligrams of magnesium (37% RDA).

2. Legumes
Black beans (boiled): 1/2 cup = 60 milligrams of magnesium (15% RDA).
Edamame (cooked, prepared): 1/2 cup = 50 milligrams of magnesium (12% RDA).
Lima beans (cooked): 1/2 cup = 40 milligrams of magnesium (10% RDA).

3. Fiber-rich whole grains
Quinoa (cooked): 1/2 cup = 60 milligrams of magnesium (15% RDA).
Shredded wheat (plain, unfrosted): 1 cup = 56 milligrams of magnesium (14% RDA).

4. Low-fat dairy products
Milk (nonfat): 1 cup = 24-27 milligrams of magnesium (7% RDA).
Yogurt (plain, low fat): 8 oz. = 42 milligrams of magnesium (10% RDA).

5. Greens
Spinach (cooked): 1/2 cup = 78 milligrams of magnesium (19% RDA).

6. Chocolate
Dark chocolate (70-85% cocoa): 1 oz. = 64 milligrams of magnesium (16% RDA).

[viewfromthefrontier]

21. Epsom salt bath

[Buttons12]

A friend of mine, 40-something, takes Doan’s Pills for backache. I think it’s magnesium salicylate. Says it’s 1000x more effective than everything else she’s tried.

[McGavin999]

I take Natural Calm it helps you sleep, makes sure you don’t get leg cramps and is high in magnesium carbonate, calcium, Vitamin C, Vitamin D and just mixes in warm water to take before bed.

[SgtHooper]

Most people get more than enough magnesium from foods and do not need to take magnesium supplements. Excessive use of magnesium supplements can be toxic. In addition to what you get from food, the highest dose you should take of magnesium supplements is:

65 mg/day for children ages 1-3
110 mg/day for children ages 4-8
350 mg/day for adults and children ages 9 and up
These doses are the highest anyone should add to their diet. Many people ingest significant quantities of magnesium through the foods they eat. It’s safe to get high levels of magnesium naturally from food, but adding large amounts of supplements to your diet can prove dangerous. Do not exceed these maximum advised levels.

[ConservativeMind]

“Magnesium deficiency is very rare and supplements are rarely needed.”

Studies prove otherwise:

Suboptimal magnesium status in the United States: are the health consequences underestimated?

https://pubmed.ncbi.nlm.nih.gov/22364157/

Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis

https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5786912/

Where did you hear that “magnesium deficiency is very rare?”

[linMcHlp]

bttt