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Spike protein accumulates in the brain and causes infarcts, bleeds, inflammation - Pfizer & Moderna COVID-19 mRNA vaccines cause severe neurological injuries
Dr. William Makis MD ^ | 4/7/2023 | Dr. William Makis MD

Posted on 04/07/2023 6:52:37 PM PDT by george76

A new paper from Germany posted on April 5, 2023 proves that the spike protein accumulates in the brain and causes death of brain cells (which would certainly explain a great deal of what we see around us). (click here)

Key findings:

“Our results revealed the accumulation of the spike protein in the skull marrow, brain meninges, and brain parenchyma.”

“The injection of the spike protein alone caused cell death in the brain, highlighting a direct effect on brain tissue.”

“we observed the presence of spike protein in the skull of deceased long after their COVID-19 infection, suggesting that the spike’s persistence may contribute to long-term neurological symptoms”

Spike protein damage:

Out of all COVID-19 viral proteins, only the spike protein was detected in brain parenchyma.

“suggesting that the spike protein could have a long lifetime in the body. This notion is supported by the observation that spike protein can be detected on patient immune cells more than a year after the infection - a recent preprint suggests spike protein’s persistence in plasma samples up to 12 months post-diagnosis”

“injection of spike protein induced a broad spectrum of proteome changes in the skull marrow, meninges, and brain, including proteins related to coronavirus disease, complement and coagulation cascades, neutrophil degranulation, NETs formation, and PI3K-AKT signaling pathway, demonstrating the immunogenicity of SARS-CoV-2 spike protein in the absence of other viral components.”

Brain inflammation.

“Our molecular analysis suggests activation of immune response in the skull-meninges-brain axis, potentially via recruiting and increasing the activity of neutrophils similar to what has been reported in the respiratory tract”

“in the skull marrow…viral proteins act as an inflammatory stimulus that leads to the development of a significant immune response in the brain”

“In the meninges, a significant consequence of the inflammatory state is an upregulation of proteins involved in neutrophil degranulation”

“Proteins related to the neurodegeneration pathway and damage to the blood-brain barrier were the most prominent dysregulated molecules in the brain.”

“viral spike protein leads to the activation of RHOA, which triggers the disruption of blood–brain barrier”

Blood clots, mini-strokes, brain bleeds..

“The dysregulation of the complement and coagulation pathways was detected in both the skull marrow and the brain. This might explain the observed propensity of COVID-19 patients to develop mini-infarcts in the brain parenchyma and our observation of an increased level of micro-bleedings in COVID-19 patients, potentially contributing to the observed brain damage in the COVID-19 patients in acute or chronic stages”

Spike protein and Neurological diseases..

“We identified several candidate proteins with no previous association with COVID-19, especially those earlier associated with neurological diseases…notably, their role has been associated with disorders such as Parkinson’s disease, Alzheimer’s disease, and dementia”

“To further pinpoint the consequences of spike protein-specific effects in the brain tissue beyond the acute inflammatory response…We identified several dysregulated proteins associated with neurodegeneration”

“significantly impairs mitochondrial function…a source of oxidative stress reported in…long-term symptoms such as chronic fatigue”

How Spike protein gets into the brain..

“Our data may also suggest a mechanism for the virus’s entry into the central nervous system. In both mouse and COVID-19 human tissues, we find spike protein in the SMCs (skull-meninges connection), which the virus or virus components could use to travel from the skull marrow to the meninges and the brain parenchyma”

“virus might take other routes to reach the brain in a not mutually exclusive way. For example, the virus could traverse the cerebrovasculature to reach the brain parenchyma or be carried there by immune cells (via neutrophils or phagocytic cells)”

“Brain invasion of virus-shed spike protein found in some COVID-19 cases has been linked to a compromised blood-brain barrier and trafficking along the olfactory nerve or vagus nerve. Here, we suggest an alternative scenario wherein SARS-CoV-2 spike protein reaches first the skull marrow and then the meninges before entering the brain.”

“Spike-induced alterations in the skull-meninges-brain axis present diagnostic and therapeutic opportunities as both skull and meninges are easier to access than brain parenchyma”

My substacks on psychosis post COVID-19 vaccination:

March 9, 2023 - Children who were injured by Pfizer or Moderna COVID-19 mRNA vaccines - Hallucinations, self-harm, suicide attempts, permanent disability (click here)

March 8, 2023 - COVID-19 vaccine induced psychosis - 13 cases of post vaccine psychosis, mania & suicide attempts that will shock you..

My Take…

This is an extremely important paper from Germany (we will never see this kind of research done in Canada).

This paper proves that the SARS-CoV2 and COVID-19 mRNA vaccine spike protein enter the skull marrow, meninges and the brain parenchyma.

The spike protein disrupts the blood brain barrier.

The spike protein alone causes cell death in the brain, it activates complement and coagulation pathways that lead to blood clots, mini infarcts and brain bleeds, it causes inflammation, and local changes associated with neurodegeneration (dementia, Alzheimer’s, Parkinson’s Diseases).

I believe that neurological injury is one of the biggest categories of COVID-19 mRNA vaccine injury. These injuries are extremely common, and we have only begun to see the long term effects of spike protein accumulation in the brain.

Beyond the strokes, aneurysms and brain bleeds, the vision and audiovestibular problems, all kinds of paralysis and movement disorders, I believe that among the COVID-19 mRNA vaccinated, we will see a huge spike in neurodegenerative disorders, mental health disorders and an overall increased risk of suicide.


TOPICS: Conspiracy; Health/Medicine; Science; Weird Stuff
KEYWORDS: adverseevents; ama; bigpharma; bigpharmatrollshere; bioweapon; bloodclots; brain; brainbleeds; braincells; chinavirus; chinavirusvaccine; covid19; death; deathjabs; deathshots; ecg; ekg; electrocardiogram; experimental; faa; frindecline; genetherapy; germany; getsumlearnin; heartinflammation; ivermectin; mediumrare; mediumwell; mrna; mrnagenetherapy; myocarditis; neurologic; neurological; nutcase; pericarditis; pilots; poison; qtardfantasy; quack; qvirus; rare; rona; sads; safelydefective; semicallcenter; spikeprotein; stroke; strokes; substackingdollars; suddenly; suicides; trypanophobia; vaccine; vaccineinjury; vax; vaxx; vaxxed; vaxxes
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1 posted on 04/07/2023 6:52:37 PM PDT by george76
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To: george76

Would explain Covid Brain Fog, or “How to Make People More Stupider “. In my case, Becoming Ordinary is driving me to near panic, especially the falling down part.


2 posted on 04/07/2023 6:55:23 PM PDT by drSteve78 (Je suis Deplorable STILL . )
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To: george76

So what can be done to clear the body of this Fauxcy promulgation of the Spike protein?


3 posted on 04/07/2023 6:56:38 PM PDT by Paladin2
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To: george76

I believe that neurological injury is one of the biggest categories of COVID-19 mRNA vaccine injury. These injuries are extremely common, and we have only begun to see the long term effects of spike protein accumulation in the brain.

Beyond the strokes, aneurysms and brain bleeds, the vision and audiovestibular problems, all kinds of paralysis and movement disorders, I believe that among the COVID-19 mRNA vaccinated, we will see a huge spike in neurodegenerative disorders, mental health disorders and an overall increased risk of suicide.


Horrific.

And, the AMA, BigPharma owned Hospital system docs, and, FRocs/$hills will deny, defend and offer cover for.


4 posted on 04/07/2023 6:59:49 PM PDT by Jane Long (What we were told was a conspiracy theory in ‘20 is now fact. Land of the sheep, home of the knaves)
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To: george76

Wait a minute...long term problems from an experimental gene therapy that was rushed out without long term safety studies and which coincided with an explosion in near term reported side effects including thousands of deaths that were systematically downplayed and dismissed by those in charge of its safety? Golly who would have thought?


5 posted on 04/07/2023 6:59:55 PM PDT by AndyTheBear
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To: Paladin2

Here are the Frontline Doctor’s (real docs) recommendations....

https://covid19criticalcare.com/treatment-protocols/i-recover/


6 posted on 04/07/2023 7:01:14 PM PDT by Jane Long (What we were told was a conspiracy theory in ‘20 is now fact. Land of the sheep, home of the knaves)
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To: george76

The Experimental mRNA Gene Therapy is just a modern German shower.


7 posted on 04/07/2023 7:06:05 PM PDT by bray (Order at TheRepublicofTexas.store)
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To: Jane Long

Scientist agree with whoever is funding them.


8 posted on 04/07/2023 7:06:10 PM PDT by george76 (Ward Churchill : Fake Indian, Fake Scholarship, and Fake Art)
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To: All

Plus eye infections and possible blindness.


9 posted on 04/07/2023 7:06:41 PM PDT by BipolarBob (Not my fault, yer Honor. I went to the Alec Baldwin School of Firearms Handling. )
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To: george76

We have the best scientists money can buy.


10 posted on 04/07/2023 7:07:09 PM PDT by BipolarBob (Not my fault, yer Honor. I went to the Alec Baldwin School of Firearms Handling. )
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To: Jane Long
I believe that neurological injury is one of the biggest categories of COVID-19 mRNA vaccine injury. These injuries are extremely common, and we have only begun to see the long term effects of spike protein accumulation in the brain.

There wasn't a word in there about vaccines.

The damage being noted is from spike proteins from Covid infection.

Seems one would want to do everything they could to avoid or reduce the severity of infection from such a virus.

11 posted on 04/07/2023 7:08:51 PM PDT by semimojo
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To: semimojo

Huh?


12 posted on 04/07/2023 7:17:44 PM PDT by chuck allen
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To: semimojo

There wasn’t a word in there about vaccines.

/\

The damn shot programs the cells to create spikes, so just quit playing dumb.

You’re such a Tool.

Not a semi tool
A fully automatic tool.

.


13 posted on 04/07/2023 7:19:47 PM PDT by cuz1961 (USCGR Veteran )
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To: george76

LOL. My computer font is set on 175% on a good day. I won’t talk about all the other problems that occurred immediately following the Moderna shots. For a while I thought I was experiencing the onset of Alzheimer’s as well. Just having entered our 60s, the wife and I shouldn’t be living like we are in our 80’s. Seriously, WTF did they do to us?


14 posted on 04/07/2023 7:20:50 PM PDT by Dogbert41
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To: BipolarBob
Plus eye infections and possible blindness.

Eye doc here. Could you please give me a source?

Ain't see it.

15 posted on 04/07/2023 7:22:33 PM PDT by lizma2
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To: semimojo

Really?? Try reading the paper. This is a quote, “This paper proves that the SARS-CoV2 and COVID-19 mRNA vaccine spike protein enter the skull marrow, meninges and the brain parenchyma.”

How about this quote, “I believe that neurological injury is one of the biggest categories of COVID-19 mRNA vaccine injury.”

How about quote number three, “I believe that among the COVID-19 mRNA vaccinated, we will see a huge spike in neurodegenerative disorders, mental health disorders and an overall increased risk of suicide.”


16 posted on 04/07/2023 7:24:23 PM PDT by OHPatriot (Si vis pacem, para bellum)
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To: george76

I wonder if this has anything to do with the rise in suicides among young people?

Children as young as eleven and twelve are suiciding.

This was unheard of just one generation ago.


17 posted on 04/07/2023 7:24:44 PM PDT by miserare ( Impeach Joe Biden!)
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To: SecAmndmt; datura; Fractal Trader; bagster; grey_whiskers; metmom; Jane Long; tatown; ...

PING


18 posted on 04/07/2023 7:25:32 PM PDT by ransomnote (IN GOD WE TRUST)
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To: lizma2

Just anecdotal.I have a SIL with a serious eye infection. Ever since she’s had the jab, she’s had Covid multiple times and several colds and now this eye problem. There might not be a connection . . . but then again there might be. Obviously something is lacking with her immune system.


19 posted on 04/07/2023 7:31:22 PM PDT by BipolarBob (Not my fault, yer Honor. I went to the Alec Baldwin School of Firearms Handling. )
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To: semimojo

al injury is one of the biggest categories of COVID-19 mRNA vaccine injury. These injuries are extremely common, and we have only begun to see the long term effects of spike protein accumulation in the brain.
There wasn’t a word in there about vaccines.

The damage being noted is from spike proteins from Covid infection.

Seems one would want to do everything they could to avoid or reduce the severity of infection from such a virus.


Only, wrong.

Because you didn’t take the time to read the study, $hot $hill troll.

Here you go, lazy troll ....

...“injection of spike protein induced a broad spectrum of proteome changes in the skull marrow, meninges, and brain,.....

The damage being done is from injections. Multiple studies have been done proving the huge difference of spike proteins, between natural infection (they don’t travel to every major organ) and these horrid $hots (they DO travel to brain...as in this study.....heart....lungs...other organs).

Seems everyone SHOULD want to everything they could to AVOID THESE DANGEROUS $HOTS.

The best way to reduce infection/severity of infection, with China Virus, is to take PROVEN safe and effective preventatives and treatments.....at least when it was even a threat. Now, china virus is primarily a threat to the jabbed.

How many jabs have you had? Your defense/denial of these terrible $hots makes it sound like you’ve had several.


20 posted on 04/07/2023 7:31:23 PM PDT by Jane Long (What we were told was a conspiracy theory in ‘20 is now fact. Land of the sheep, home of the knaves)
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