Posted on 04/25/2023 8:31:27 AM PDT by ConservativeMind
A study has found that compared with standard antibiotic treatment, stool transplantation can increase the number of people recovering from Clostridioides difficile (C. diff) infection, a condition that causes potentially life-threatening diarrhea. Within the study, 77% of people who received a stool transplant did not experience reinfection within eight weeks, compared to 40% of those who received antibiotics alone.
Transplanting healthy donor stool into a gut with dysbiosis is intended to balance the gut microbes and reestablish a healthy microbiome, thus significantly reducing the risk of C. diff recurring. The US FDA has recently approved a stool transplant product for prevention of recurrence of C. diff that can be administered as enema.
The new Cochrane Review, examined data from six clinical trials with a total of 320 adults that assessed the efficacy and safety of stool transplantation for the treatment of repeated C. diff infection. Most of the included studies compared stool transplantation with a standard antibiotic treatment using vancomycin, which is commonly used for this kind of infection.
The review found that stool transplantation leads to a larger increase in resolution of repeated infections of C. diff than other treatments studied, as well as a decrease in side effects when compared with standard treatment using antibiotics.
"After a person with a C. diff infection gets treated with antibiotics, there is about a 25% chance that they will have another episode of C. diff infection in the next 8 weeks," Imdad said. "The risk of recurrence increases to about 40% with the second episode and to nearly 60% with the third episode. So, once you are in this cycle, it gets more and more difficult to break out of it. Stool transplants can reverse the dysbiosis and thus decrease the risk of recurrence of the disease."
(Excerpt) Read more at medicalxpress.com ...
Medical science now officially says says doctors and insurance companies can freely consider poop transplants to help people with C. diff. Before today, doctors who considered this were heretical and should have been virtually stoned.
Back to leeches and maggots, it seems.
Not that there’s anything wrong with that.
No thanks. I’d take my chances with the recurring infections.
Leeches and maggots both have their places in medicine.
What I find interesting is that before today, doctors who considered or did this were looked at as crazy, but as of today, they are considered crazy if they don’t do it.
It just takes one second of time to flip what’s crazy, for years, to the exact opposite.
Effect of fecal microbiota transplantation in children with autism spectrum disorder: A systematic review
https://pubmed.ncbi.nlm.nih.gov/36937721/
Apparently fecal transplant has some effectiveness in autism too.
Wonder if what we are eating or drinking these days is part of the problem?
This actually has a fairly good outcome despite it smelling like poop.
...or go work on a farm for a week while not washing your hands.
I would say what we ingest is key to 80+% of everything to our health, but it’s very hard to know everything we need, all the time.
I’ve had many c-diff infections after IV antibiotics in hospital due to diverticulitis. Painful. Horrible. You try to get close relatives to donate. I will try it if I can find a donor. That seems unlikely. Vancomycin is the best choice now.
Im a donor, I get 175 bucks per donation
Transplant?
Sounds better than eating poop!
You’re sh!tting me, right? /s
I just tried it - so far nothing is happening.
Not really, but kinda similar.
They’ve also discovered the healthy bowel generates chemicals necessary to a healthy and well functioning brain which means good mental health.
Schizophrenia is one of those conditions that a turd transplant can help.
I transplant mine into the terlet.
“...turd transplant...”
Thanks for that imagery... :)
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