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Altered Mouse Turns 136 in Human Years
AP Science via Yahoo ^ | April 12, 2004 | Anon AP Science Stringer

Posted on 04/12/2004 6:07:58 PM PDT by Pharmboy

ANN ARBOR, Mich. - A dwarf mouse named Yoda has celebrated his fourth birthday, making him the oldest of his kind and far beyond 100 in human years, the University of Michigan Medical School says.

Yoda owes his longevity to genetic modifications that affected his pituitary and thyroid glands and reduced insulin production — and which left him a third smaller than an average mouse and very sensitive to cold.

On the other hand, at the human equivalent of about 136 years, Yoda is still mobile, sexually active and "looking good," said Dr. Richard A. Miller, associate director of research at the school's geriatrics center.

Yoda lives in a carefully maintained lab with roughly 100 other male geriatric mice being used for a lifespan study. An average lab mouse lives slightly more than two years.

Yoda's cage mate, Princess Leia, is a much larger female who uses her body warmth to keep the dwarf mouse from freezing to death.

Researchers are studying the genetic mutants to determine how altered hormone levels can slow the aging process, with the hope of figuring out which methods, if any, eventually could be applied to humans.

___


TOPICS: Culture/Society; Front Page News; US: Michigan
KEYWORDS: aging; health; mice; sex
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One hundred and thirty-six and still having sex. I'll take it.
1 posted on 04/12/2004 6:08:00 PM PDT by Pharmboy
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To: Pharmboy
But I'd hate to give up height.
2 posted on 04/12/2004 6:11:46 PM PDT by Paleo Conservative (Do not remove this tag under penalty of law.)
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To: Pharmboy
136? They have to do better than that before I go along with any altering.
3 posted on 04/12/2004 6:16:55 PM PDT by Graymatter
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To: Pharmboy
When 900 years old we reach, be as active we will not!
Yoda and Princess Leia?!?!
At least they're the same species in RL. Thank God Lucas didn't go THERE!
4 posted on 04/12/2004 6:18:11 PM PDT by ClearBlueSky (Whenever someone says it's not about Islam...it's about Islam.)
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To: Pharmboy
I'm 87 and don't need Viagra....so what's the big deal?
5 posted on 04/12/2004 6:28:31 PM PDT by KnutCase
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To: Pharmboy
That beats Mickey Mouse.
6 posted on 04/12/2004 6:32:31 PM PDT by Mathlete
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To: Pharmboy
puny but potent?
7 posted on 04/12/2004 6:40:17 PM PDT by nuconvert ("America will never be intimidated by thugs and assassins." ( President Bush 3-20-04))
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To: Pharmboy
"and which left him a third smaller than an average mouse and very sensitive to cold.

On the other hand, at the human equivalent of about 136 years, Yoda is still mobile, sexually active and "looking good," said Dr. Richard A. Miller, associate director of research at the school's geriatrics center."

Sounds like Florida to me.
8 posted on 04/12/2004 6:41:06 PM PDT by Lokibob (All typos and spelling errors are mine and copyrighted!!!!)
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To: Pharmboy
To Princess Leia, size doesn't matter.
9 posted on 04/12/2004 6:41:27 PM PDT by nuconvert ("America will never be intimidated by thugs and assassins." ( President Bush 3-20-04))
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To: Pharmboy
I don't know about "sexually active," of course, but I think our waitress tonight was 130.

There's just something wrong about a lady of that age waiting tables...I felt guilty, like I was supposed to get up and help Grandma with that tray....
10 posted on 04/12/2004 6:48:09 PM PDT by Triple Word Score (Meretriciousness Everywhere.)
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To: ClearBlueSky
Look at me, judge me, by size do you?

And well you should not, for my ally is reduced insulin production and genetic changes to my pituitary and thyroid glands. ANd a powerful ally it is.

11 posted on 04/12/2004 6:51:11 PM PDT by Skywalk
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To: Pharmboy; Graymatter
Too late to make that choice. You have already been born and your genetic make up is pretty much set in stone.
12 posted on 04/12/2004 6:52:45 PM PDT by Pontiac (Ignorance of the law is no excuse, ignorance of your rights can be fatal.)
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To: Pharmboy
Altered Mouse Turns 136 in Human Years

Demands Medical, Prescription and Cheese benefits

13 posted on 04/12/2004 6:53:42 PM PDT by freedumb2003 (If your cat has babies in the oven you don't call them biscuits!)
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To: Pharmboy

Mr. Jingles

14 posted on 04/12/2004 6:56:33 PM PDT by Merdoug
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To: Pharmboy
"Yoda Kerry"? What an unusual name for a mouse that wears an athletic supporter.

Oh, sensitive to cold, so never mind. Wrong mouse.
15 posted on 04/12/2004 6:58:00 PM PDT by SwyChron 101 (The Smoker You Drink, the Player You Get)
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To: Pharmboy
... a third smaller than an average mouse"

For YEARS I've maintained that shorter people are more energy efficient!!!

HA! I win!

We short folks use less natural resources to sustain the same size soul as you tall folks.

Less food to feed us...
Less material to clothe us...
Less air and water to sustain us...
..and think how much less material it would make to make houses a couple of feet shorter!

:.) I'm so right.

16 posted on 04/12/2004 7:09:34 PM PDT by bannie (The government which robs Peter to pay Paul can always depend upon the support of Paul.)
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To: Pharmboy

Here's the lovely couple. Yoda is on the left.

17 posted on 04/12/2004 7:09:35 PM PDT by Slings and Arrows (Am Yisrael Chai!)
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To: All
P.S. I could be wrong, but doesn't it look like Yoda's gotten Princess Leia in a family way?
18 posted on 04/12/2004 7:13:00 PM PDT by Slings and Arrows (Am Yisrael Chai!)
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To: Slings and Arrows
She has a startled look on her face...
19 posted on 04/12/2004 7:42:45 PM PDT by Pharmboy (History's greatest agent for freedom: The US Armed Forces)
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To: Slings and Arrows
Active....you mean a "little" active.

He has VERY little paws, too.

20 posted on 04/12/2004 7:46:28 PM PDT by Sacajaweau (God Bless Our Troops!!)
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