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Vioxx. Celebrex. Now Aleve. What's a Patient to Think?
NY Times ^ | December 28, 2004 | ANAHAD O'CONNOR

Posted on 12/29/2004 12:38:09 PM PST by neverdem

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1 posted on 12/29/2004 12:38:09 PM PST by neverdem
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To: neverdem
Shut-up and take the pills! As directed. Don't take more than recommended. Don't take the maximum for years on end. Don't exceed the maximum by two, three, four times!

Or just live with the pain!

2 posted on 12/29/2004 12:39:57 PM PST by newzjunkey (Demand Mexico Turnover Fugitive Murderers: http://www.escapingjustice.com)
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To: neverdem
She flushed her Vioxx down the toilet in September, after it was withdrawn from the market, and switched to Celebrex. But when problems surfaced with Celebrex this month, she had to stop that, too.

My dad had to take a similar course of action.
He has had arthritis since he was my age (34).

Now he is in pain most of the time and doesn't know what he should take.

3 posted on 12/29/2004 12:40:24 PM PST by Constitution Day (Free presidio9!)
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To: neverdem

Your heart will explode, but you won't feel pain....


4 posted on 12/29/2004 12:41:09 PM PST by alloysteel ("Master of the painfully obvious.....")
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To: neverdem
Dunno 'bout anybody else, but I bought some naproxin sodium (Aleve) as soon as I head the news. That is great stuff and the side effects don't matter much.
5 posted on 12/29/2004 12:43:23 PM PST by Little Ray (I'm a reactionary, hirsute, gun-owning, knuckle dragging, Christian Neanderthal and proud of it!)
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To: Constitution Day

He should take vioxx (if he has any left), celebrex, or alleve at the lower-scale of the recommended doses.

Perhaps cycle them . .. 10 days one, 10 days the next.

IN ALL PROBABILITY, this is JUNK SCIENCE. The test are for SOME people at HIGH doses.

In sum, because .01% of the people have problems 99.99% will be in pain so the drug companies can (senisbly, from their persepctive) avoid lawsuits.


6 posted on 12/29/2004 12:46:26 PM PST by MeanWestTexan
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To: neverdem
What's a Patient to Think?

This patient thinks that the FDA/Pharma complex has become way too cozy.

FDA funding now comes directly from pharmaceutical companies, and they get no further funding from drugs that they do not approve.

When a drug company enrolls a new product for FDA approval, they also hand over $500,000 for oversight expenses, and they keep handing over more and more money until the drug is either approved or terminated.

The FDA is not an independent body. They routinely gag investigators who raise alarms about new products.

That is EXACTLY how the Vioxx episode occurred. The people in the FDA who were against its approval were ordered to shut up.

Abolish the FDA.

Trial lawyers are the scum of the earth, but at least they are independent of the pharmaceutical companies.

Sad to say, drug regulation by lawsuit is a lot more honest and effective than drug regulation by the FDA.

7 posted on 12/29/2004 12:47:19 PM PST by E. Pluribus Unum (Drug prohibition laws help fund terrorism.)
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To: neverdem

Holy Crap!


8 posted on 12/29/2004 12:47:24 PM PST by bedolido (I can forgive you for killing my sons, but I cannot forgive you for forcing me to kill your sons)
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To: Constitution Day

Convince your Dad to get back on Celebrex. Seriously. I mean, what's the big deal? An increased risk of heart attack---even though the risk remains low---versus constant pain. I'll tell you what I'd pick at his age.


9 posted on 12/29/2004 12:48:31 PM PST by mcg1969
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To: neverdem

bttt


10 posted on 12/29/2004 12:48:40 PM PST by malia (a cherished constitutional right -- the right to vote!)
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To: neverdem

Stick to a glass of wine and a couple of Advils.


11 posted on 12/29/2004 12:49:47 PM PST by 1Old Pro
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To: mcg1969

My dad is 59.
He lost his favorite brother a few years back to a massive heart attack, and heart disease runs in my family.
He hasn't mentioned it but I am sure that's his motivation for quitting both.

My mom has tried to convince him to stay on the Celebrex but he's quite stubborn, just like his son. ;)


12 posted on 12/29/2004 12:50:43 PM PST by Constitution Day (Free presidio9!)
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To: neverdem
It was the third painkiller in four months that Ms. Eisen, who has degenerative spine and disk disease, had quit abruptly because of studies linking the drugs to heart attacks. She flushed her Vioxx down the toilet in September, after it was withdrawn from the market, and switched to Celebrex. But when problems surfaced with Celebrex this month, she had to stop that, too.

Did she maybe talk to her doctor before she took such drastic measures?
13 posted on 12/29/2004 12:51:00 PM PST by Xenalyte (Who you tryin' to get crazy with, ese? Don't you know I'm loco?)
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To: newzjunkey

It isn't that simple. My father-in-law had been taking Vioxx and Celebrex for a about a year for pain, both at different times. Since his pain threshold was so high (he also took valium for pain at times that did not touch it) he was instructed to take higher doses by his doctors. He was a Marine who was a radio operator in Vietnam and who had endured more medical issues since then than most can imagine. He never complained, just did what the doctors told him to.

He passed away on December 2 from a massive heart attack. As painful as that has been, hearing about the dangers of these drugs after we had just buried this proud Marine hurt worse. Of course, he was doing just what the doctors told him to do. They were advising him based on the manufacturer's recommendations, which said higher doses were safe. Now we know differently.

BTW - The ONLY over the counter medication he ever took for anything pain related was Aleve, since his son, my brother-in-law, worked at Bayer where it was made.


14 posted on 12/29/2004 12:51:10 PM PST by Littlejon
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To: Littlejon

Oh yeah, my father-in-law was 59 years old. He was an athlete in his younger days, though with only one leg he was confined to a wheelchair the last 6 years. Overall, however, he was relatively healthy and his family has no history of heart problems.


15 posted on 12/29/2004 12:53:02 PM PST by Littlejon
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To: Constitution Day

Well, hey, we've all gotta make our own choices, I guess. All I know is that both Vioxx and Celebrex have been a godsend to many in severe pain. Seems the risk ought to be worth it for many, maybe even your dad.
All the best!


16 posted on 12/29/2004 12:54:16 PM PST by mcg1969
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To: Constitution Day
Now he is in pain most of the time and doesn't know what he should take.

Hmmm, my doctorate isn't in medicine (heh heh), however: live life in continous pain... or accept a slight risk of increased chance of heart attack?

I know what my choice would be, and it isn't the former. Or become long-term opiate user; studies have shown there is little overall risk with long-term moderate dose opiates, and the people taking it are perfectly functional (i.e., not off in lala-land).

17 posted on 12/29/2004 12:54:54 PM PST by IonImplantGuru (PhD, School of Hard Knocks)
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To: neverdem

Unfortunately many Americans do not realize (with their instant-gratification minds) that their is virtue in suffering.


18 posted on 12/29/2004 12:55:20 PM PST by Salvation (†With God all things are possible.†)
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To: neverdem
"What's a patient to think?"

THINK OPIATES!!

w00t w00t lol.


....then stop thinking all together lol.
19 posted on 12/29/2004 12:55:36 PM PST by KoRn
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To: Constitution Day
My doctor recommended I give my teenage son aspirin for his headaches. Aspirin works great on arthritis, too. If it bothers his stomach, he can take a coated or buffered brand.

No one touts aspirin anymore because it's old news and remarkably cheap. But, it still works.
20 posted on 12/29/2004 12:55:42 PM PST by keats5
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