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Physics explains biology - Action of nerves is based on sound pulses
What's Next | University of Copenhagen ^ | 3/7/07

Posted on 03/08/2007 9:40:58 AM PST by LibWhacker

Danish scientists challenge the accepted scientific views of how nerves function and of how anesthetics work. Their research suggests that action of nerves is based on sound pulses and that anesthetics inhibit their transmission.

Every medical and biological textbook says that nerves function by sending electrical impulses along their length. "But for us as physicists, this cannot be the explanation. The physical laws of thermodynamics tell us that electrical impulses must produce heat as they travel along the nerve, but experiments find that no such heat is produced," says associate professor Thomas Heimburg from the Niels Bohr Institute at Copenhagen University.


Image: shows a biological membrane at its melting point. The green molecules are liquid, and the red are solid. Molecules of anesthetic reduce the number of red areas so that the sound pulse can no longer transport its signal. The nerve is anesthetized.

He received his Ph.D. from the Max Planck Institute in Göttingen, Germany, where biologists and physicists often work together – at most institutions these disciplines are worlds apart. Thomas Heimburg is an expert in biophysics, and when he came to Copenhagen, he met professor Andrew D. Jackson, who is an expert in theoretical physics. They decided to work together in order to study the basic mechanisms which govern the way nerves work.

Physics explains biology

Nerves are 'wrapped' in a membrane composed of lipids and proteins. According to the traditional explanation of molecular biology, a pulse is sent from one end of the nerve to the other with the help of electrically charged salts that pass through ion channels in the membrane. It has taken many years to understand this complicated process, and a number of the scientists involved in the task have been awarded the Nobel Prize for their efforts. But – according to the physicists – the fact that the nerve pulse does not produce heat contradicts the molecular biological theory of an electrical impulse produced by chemical processes. Instead, nerve pulses can be explained much more simply as a mechanical pulse according to the two physicists. And such a pulse could be sound. Normally, sound propagates as a wave that spreads out and becomes weaker and weaker. If, however, the medium in which the sound propagates has the right properties, it is possible to create localized sound pulses, known as "solitons", which propagate without spreading and without changing their shape or losing their strength.

The membrane of the nerve is composed of lipids, a material that is similar to olive oil. This material can change its state from liquid to solid with temperature. The freezing point of water can be lowered by the addition of salt. Likewise, molecules that dissolve in membranes can lower the freezing point of membranes. The scientists found that the nerve membrane has a freezing point, which is precisely suited to the propagation of these concentrated sound pulses. Their theoretical calculations lead them to the same conclusion: Nerve pulses are sound pulses.

Anesthetized by sound

How can one anesthetize a nerve so that feel ceases and it is possible to operate on a patient without pain? It has been known for more than 100 years that substances like ether, laughing gas, chloroform, procaine and the noble gas xenon can serve as anesthetics. The molecules of these substances have very different sizes and chemical properties, but experience shows that their doses are strictly determined by their solubility in olive oil. Current expertise is so advanced that it is possible to calculate precisely how much of a given material is required for the patient. In spite of this, no one knows precisely how anesthetics work. How are the nerves "turned off"? Starting from their theory that nerve signals are sound pulses, Thomas Heimburg and Andrew D. Jackson turned their attention to anesthesia. The chemical properties of anesthetics are all so different, but their effects are all the same - curious!

But the curious turned out to be simple. If a nerve is to be able to transport sound pulses and send signals along the nerve, its membrane must have the property that its melting point is sufficiently close to body temperature and responds appropriately to changes in pressure. The effect of anesthetics is simply to change the melting point – and when the melting point has been changed, sound pulses cannot propagate. The nerve is put on stand-by, and neither nerve pulses nor sensations are transmitted. The patient is anesthetized and feels nothing.

Source: University of Copenhagen


TOPICS: Miscellaneous
KEYWORDS: anesthetics; biology; nerves; physics; pulses; sound
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To: Blueflag

No way. Math has no intrinsic units except numbers. Physics is about physical propertities and quantifying said physical properties. Math is physics' b*tch. ;-)


21 posted on 03/08/2007 10:52:28 AM PST by DungeonMaster (Render therefore to Caesar the things that are Caesar’s, and to God the things that are God’s.”)
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To: Right Wing Assault

I am a bass player.

Suddenly so many things make sense...


22 posted on 03/08/2007 10:54:58 AM PST by RobRoy (Islam is a greater threat to the world today than Nazism was in 1938.)
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To: LibWhacker

Absolutely. Once you understand how a thing works, you can design a weapon to destroy or at least make it non functional.

Maybe we really could create phasers that could set to stun!

Can you imagine a stun bomb set off in a "bad" neighborhood in Iraq before our guys move in?


23 posted on 03/08/2007 10:57:06 AM PST by RobRoy (Islam is a greater threat to the world today than Nazism was in 1938.)
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To: Leftism is Mentally Deranged

>>Doesn't he know that sound waves produce heat too as they travel through a substance?<<

That crossed my mind as well...


24 posted on 03/08/2007 10:57:50 AM PST by RobRoy (Islam is a greater threat to the world today than Nazism was in 1938.)
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To: ModelBreaker

No. It's not.


25 posted on 03/08/2007 11:21:22 AM PST by Psycho_Bunny (I'm holding out hope that at least the DEMOCRATS might accidentally nominate a conservative.)
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To: LibWhacker

Ahh. That explains why EEGs don't work. Acustics instead of electricity, therefore no electro-magnetic waves to pick up.

Do I need a sarc tag?


26 posted on 03/08/2007 11:34:54 AM PST by rbookward (When 900 years old you are, type as well you will not!)
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To: DungeonMaster
All science is physics.

Good point. The fuzzy "sciences" come into play only when the physics isn't well understood.

27 posted on 03/08/2007 11:48:16 AM PST by 3niner (War is one game where the home team always loses.)
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To: LibWhacker
"But for us as physicists, this cannot be the explanation. The physical laws of thermodynamics tell us that electrical impulses must produce heat as they travel along the nerve, but experiments find that no such heat is produced,"

Do these "physicists" understand that a nerve impulse is not a simple electrical current? That a spontaneous reaction need not generate heat? According to their calculations, how much heat should a nerve cell produce when it fires? And how did they measure the heat produced by a nerve cell with enough precision to rule it out? If they get this far they will have a major scientific breakthrough.

Whether they do or not, the stuff about sound might have some scientific value too. But it fails the random sentence test, so I won't bother with it until/unless they clean it up.
28 posted on 03/08/2007 11:52:12 AM PST by xenophiles
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To: LibWhacker
...The membrane of the nerve is composed of lipids, a material that is similar to olive oil. This material can change its state from liquid to solid with temperature. The freezing point of water can be lowered by the addition of salt. Likewise, molecules that dissolve in membranes can lower the freezing point of membranes. The scientists found that the nerve membrane has a freezing point, which is precisely suited to the propagation of these concentrated sound pulses. Their theoretical calculations lead them to the same conclusion: Nerve pulses are sound pulses...

Oy.

With regards to the bolded text: so can every other material.

Either the author of this article didn't have a clue about the subject as it was explained to him, or it's just a load of theoretical BS. It definitely lost something in translation.

29 posted on 03/08/2007 11:54:32 AM PST by Ranxerox
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To: LibWhacker

A scientific "consensus" that was wrong??? Can't be!


30 posted on 03/08/2007 11:58:16 AM PST by colorado tanker
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To: LibWhacker

What is the difference between an extraordinary proof and a proof? If I can prove something with a simple proof, why do they demand an extraordinary proof.

Also, "proof" is a poor word to choose for scientific use. Math does proofs. Science does experiments that either support (to varying degrees) or do not support hypotheses.


31 posted on 03/08/2007 12:09:06 PM PST by Right Wing Assault ("..this administration is planning a 'Right Wing Assault' on values and ideals.." - John Kerry)
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To: rbookward

It may eventually be shown that both theories are correct; i.e. that nerve signals consist of sound waves which are triggered by electrical impulses. Then EEGs would still work :-)


32 posted on 03/08/2007 12:15:32 PM PST by GovernmentShrinker
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To: Psycho_Bunny
No. It's not.

Ah. So you have a VERY strong prior in this one. No?

33 posted on 03/08/2007 12:19:31 PM PST by ModelBreaker
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To: LibWhacker
So does this mean that they need to re-jig the reasons why the machines enslaved us in "The Matrix"?

They have to rework that scene:

Morpheus: What is the Matrix? Control. The Matrix is a computer-generated dream world built to keep us under control in order to change a human being into this:

[holds up a Duracell battery]

[holds up an iPod]

34 posted on 03/08/2007 12:19:53 PM PST by Malsua
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To: LibWhacker
Maybe something like this could prove useful against the enemy in battle?

Check out "The Shout" by Robert Graves

35 posted on 03/08/2007 12:31:34 PM PST by Pietro
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To: ModelBreaker
Go back and read what you wrote and ask yourself if you're someone you'd respond to.

You took what I said out of context and flew off the handle about what you imagined I was saying.

I didn't even finish reading what you wrote because it was so breathlessly self-important.

36 posted on 03/08/2007 1:22:13 PM PST by Psycho_Bunny (I'm holding out hope that at least the DEMOCRATS might accidentally nominate a conservative.)
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To: RobRoy
I am a bass player.

I'm learning to play rainbow trout. ;-P

37 posted on 03/08/2007 1:34:54 PM PST by MortMan (Good health is merely the slowest possible rate at which one can die.)
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To: MortMan

>>I'm learning to play rainbow trout. ;-P<<

I can't get past the bones... ;)


38 posted on 03/08/2007 2:05:30 PM PST by RobRoy (Islam is a greater threat to the world today than Nazism was in 1938.)
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To: DungeonMaster

sure.

try physics w/o your calculator, your integrals, or your Excel macro, or SASS or ...


;-p


physics is all mechanical w/o math.


39 posted on 03/08/2007 2:42:18 PM PST by Blueflag (Res ipsa loquitor)
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