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Helpful Bacteria May Hide in Appendix
NY Times ^ | June 17, 2008 | NICHOLAS BAKALAR

Posted on 06/18/2008 9:12:40 PM PDT by neverdem

Everyone is born with one, but no one knows what it’s for. The human appendix is a small dead-end tube connected to the cecum, or ascending colon, one section of the large intestine. Everyone lives happily with it until it becomes painfully inflamed, when the only treatment is to remove it surgically.

Then everyone lives happily without it. So why is it there in the first place?

Some experts have guessed that it is a vestige of the evolutionary development of some other organ, but there is little evidence for an appendix in our evolutionary ancestors. Few mammals have any appendix at all, and the appendices of those that do bears little resemblance to the human one.

Last December, researchers published a novel explanation in The Journal of Theoretical Biology. The appendix, they suggest, is a “safe house” for commensal bacteria, the symbiotic germs that aid digestion and help protect against disease-causing germs.

Structurally, the appendix is isolated from the rest of the gut, with an opening smaller than a pencil lead, protected from the fecal stream that might be carrying pathogens. In times of trouble like a diarrheal infection that flushes the system, these commensal bacteria could hide out there, ready to repopulate the gut when the coast is clear.

William Parker, the senior author of the study and an assistant professor of surgery at Duke, emphasized that this was a hypothesis, not experimental proof. “At this point,” Dr. Parker said, “this is a deduction based on a lot of information that we’ve had for many years and some key pieces of information that have only been uncovered recently by our lab and others. It does make sense.

“But an experiment to prove this theory would be very expensive...?”

(Excerpt) Read more at nytimes.com ...


TOPICS: Health/Medicine
KEYWORDS: appendix; commensals; darwinsapologists; godsgravesglyphs; health; medicine
Biofilms in the large bowel suggest an apparent function of the human vermiform appendix



1 posted on 06/18/2008 9:12:41 PM PDT by neverdem
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To: neverdem

What an interesting idea.


2 posted on 06/18/2008 9:18:10 PM PDT by Psycho_Bunny (Islam: Imagine a clown car.........with guns.)
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To: neverdem

btt


3 posted on 06/18/2008 10:19:54 PM PDT by Marie (Why is it that some people believe everything that happens is the will of G-d - except Israel?)
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4 posted on 06/19/2008 12:42:44 AM PDT by neverdem (I'm praying for a Divine Intervention.)
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To: neverdem

Darwin strikes out again...


5 posted on 06/19/2008 4:10:11 AM PDT by AmericaUnited
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To: neverdem

I hate it when they hide in the footnotes, though.


6 posted on 06/19/2008 5:17:19 AM PDT by Jagman
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To: blam; StayAt HomeMother; Ernest_at_the_Beach; 1ofmanyfree; 21twelve; 24Karet; 2ndDivisionVet; ...

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Thanks neverdem.
there is little evidence for an appendix in our evolutionary ancestors. Few mammals have any appendix at all, and the appendices of those that do bears little resemblance to the human one.
To all -- please ping me to other topics which are appropriate for the GGG list.
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7 posted on 06/19/2008 7:38:19 AM PDT by SunkenCiv (https://secure.freerepublic.com/donate/_________________________Profile updated Friday, May 30, 2008)
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To: AmericaUnited
Darwin strikes out again...

How so?

8 posted on 06/19/2008 7:51:02 AM PDT by null and void (every Muslim, the minute he can start differentiating, carries hate of Americans, Jews & Christians)
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To: neverdem

It would be rather easy to compare two groups; those with appendix and those that have removed them with respect to intestinal infections etc.


9 posted on 06/19/2008 7:55:23 AM PDT by AdmSmith
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To: neverdem

“Helpful Bacteria May Hide in Appendix”

Yeah, well, *I’m* not going in after them!


10 posted on 06/19/2008 8:00:32 AM PDT by BibChr ("...behold, they have rejected the word of the LORD, so what wisdom is in them?" [Jer. 8:9])
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To: neverdem

Yakult


11 posted on 06/19/2008 8:38:40 AM PDT by BunnySlippers
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To: null and void

“long thought vestigial”


12 posted on 06/19/2008 8:42:28 AM PDT by AmericaUnited
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To: AdmSmith
It would be rather easy to compare two groups; those with appendix and those that have removed them with respect to intestinal infections etc.

Yes. That's how they eventually figured out that the spleen actually does occasionally matter.

That took decades.

This might take longer, as societies with enough of an understanding of basic sanitation to allow people to survive an appendectomy also have much, much lower rates of bouts of severe diarrhea.

13 posted on 06/19/2008 8:44:19 AM PDT by null and void (every Muslim, the minute he can start differentiating, carries hate of Americans, Jews & Christians)
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To: AmericaUnited
That's a bit of a stretch.

The other end of that same stick is we still have appendices (well, maybe you do, I don't) because we still need them. If they were truly vestigial they would eventually go away especially since they do case often lethal problems.

For example, left untreated my appendicitis would have prevented me from passing on my genes. There must be some offsetting advantage to compensate for the losses caused by appendices, or the occasional freak born without one would take over the gene pool.

Die of appendicitis? Die of the after effects of diarrhea? Multiple bouts of diarrhea remains a very popular way for small children to die world wide, even with an appendix to repopulate the gut after the first mild case.

Like Perfect Creation, Evolution predicts that everything has a function. We may occasionally discover the function where it isn't glaringly obvious. This looks like one of those cases.

14 posted on 06/19/2008 8:59:02 AM PDT by null and void (every Muslim, the minute he can start differentiating, carries hate of Americans, Jews & Christians)
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To: AmericaUnited
My wife had her appendix out when she was young and then later had Irritable Bowel Syndrome. However the IBS cleared up after I married her and moved her away from her drama filled family. I wonder if with an appendix she might not have had the bouts of diarrhea?
15 posted on 06/19/2008 9:11:59 AM PDT by ME-262 (Nancy Pelosi is known to the state of CA to render Viagra ineffective causing reproductive harm.)
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To: ME-262; All

“An experiment to prove this would be very expensive.”

Perhaps it would be possible to check the infection rates of people with and without their appendix to see if having it removed causes an increase in various types and duration and frequency of illness after appendix removal.


16 posted on 06/19/2008 10:35:12 AM PDT by gleeaikin
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To: neverdem

Interesting. I have wondered what function the appendix performs. This theory, after it is studied, just might tell us what its function is.


17 posted on 06/19/2008 12:25:46 PM PDT by Dustbunny (Freedom prospers when religion is vibrant and the rule of law under God is acknowledged. The Gipper)
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