Free Republic
Browse · Search
News/Activism
Topics · Post Article

Skip to comments.

Adult Stem Cells from Fat Tissue Offer Hope for MS Treatment
LifeSiteNews ^ | 4/24/09 | LifeSiteNews

Posted on 04/24/2009 1:36:48 PM PDT by wagglebee

April 24, 2009 (LifeSiteNews.com) - A preliminary study on the use of stem cells obtained from a patient's own adipose tissue in the treatment of multiple sclerosis (MS) has shown promising results.

The three case studies, described in BioMed Central's open access Journal of Translational Medicine support further clinical evaluation of what are known as stromal vascular fraction (SVF) cells in MS and other autoimmune conditions.

Thomas Ichim, from Medistem Inc., and Dr. Boris Minev, from the Division of Neurosurgery, University of California San Diego, worked with a team of researchers to demonstrate the possible effectiveness of SVF cells in MS treatment.

Minev said, "All three patients in our study showed dramatic improvement in their condition after the course of SVF therapy. While obviously no conclusions in terms of therapeutic efficacy can be drawn from these reports, this first clinical use of fat stem cells for treatment of MS supports further investigations into this very simple and easily-implementable treatment methodology".

MS is an autoimmune condition, in which the body's own defences attack nerve cells, resulting in loss of their fatty myelin sheath. The first symptoms usually occur in young adults, most commonly in women. It is believed that SVF cells, and other stem cells, may be able to treat the condition by limiting the immune reaction and promoting the growth of new myelin.

According to Minev, "None of the presently available MS treatments selectively inhibit the immune attack against the nervous system, nor do they stimulate regeneration of previously damaged tissue. We've shown that SVF cells may fill this therapeutic gap."

Minev and his colleagues provided the SVF treatment to three patients with MS. The first had suffered frequent painful seizures for the previous three years; after treatment he reported that the seizures had stopped completely and that he had seen significant improvements in his cognition and a reduction of spasticity in his arms and legs.

The second patient reported improvements in his sense of balance and coordination, as well as an improved energy level and mood. The final patient had been diagnosed with MS in 1993. After SVF treatment in 2008, his gait, balance and coordination improved dramatically over a period of several weeks. According to Minev, "His condition continued to improve over the next few months and he is currently reporting a continuing improvement and ability to jog, run and even bicycle."


TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: adiposetissue; adultstemcells; fatcells; multiplesclerosis; prolife
If they could do this and kill babies it would be on the front page of every paper in the country.
1 posted on 04/24/2009 1:36:48 PM PDT by wagglebee
[ Post Reply | Private Reply | View Replies]

To: cgk; Coleus; cpforlife.org; narses; Salvation; 8mmMauser

Pro-Life Ping


2 posted on 04/24/2009 1:37:09 PM PDT by wagglebee ("A political party cannot be all things to all people." -- Ronald Reagan, 3/1/75)
[ Post Reply | Private Reply | To 1 | View Replies]

To: cgk

MS Ping


3 posted on 04/24/2009 1:37:20 PM PDT by wagglebee ("A political party cannot be all things to all people." -- Ronald Reagan, 3/1/75)
[ Post Reply | Private Reply | To 1 | View Replies]

To: wagglebee; Joya

Joya ping.


4 posted on 04/24/2009 1:39:53 PM PDT by Quix (POL Ldrs quotes fm1900 2 presnt: http://www.freerepublic.com/focus/religion/2130557/posts?page=81#81)
[ Post Reply | Private Reply | To 1 | View Replies]

To: wagglebee

Woohoo! Something most Americans have an abundance of (myself included :) )


5 posted on 04/24/2009 1:55:25 PM PDT by rom (Obama '12 slogan: Let's keep on hopin'!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: rom

Ditto! How do you sign up for that research?


6 posted on 04/24/2009 2:53:30 PM PDT by Ellendra (Can't starve us out, and you can't make us run...Country folks CAN survive!!! -Hank Jr.)
[ Post Reply | Private Reply | To 5 | View Replies]

To: wagglebee

Michael J. Fox should be required to wait until a cure is made from embryonic stem cells. Put his life where his mouth (and heart) is.


7 posted on 04/24/2009 2:58:19 PM PDT by TigersEye (Cloward-Piven Strategy)
[ Post Reply | Private Reply | To 1 | View Replies]

To: HonestConservative

pint


8 posted on 04/24/2009 3:44:13 PM PDT by balls (US trashing in progress - You can't take the ghetto out of 0dumbo)
[ Post Reply | Private Reply | To 1 | View Replies]

To: wagglebee; 2ndClassCitizen; algtx; bajabaja; balls; Beth; Born Conservative; cva66snipe; dawn53; ...
Thank you for the ping, wagglebee! :)

MS PING!


9 posted on 04/24/2009 8:32:05 PM PDT by cgk (I don't see myself as a conservative. I see myself as a religious, right-wing, wacko extremist.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: wagglebee

See!! God always gives us another way to accomplish something without resorting to evil.


10 posted on 04/24/2009 8:53:06 PM PDT by NellieMae (Here...... common sense,common sense,common sense,where'd ya go... common sense......)
[ Post Reply | Private Reply | To 1 | View Replies]

To: cgk
It sounds real promising. The best news yet in these type of disorders. If it does what the say then it should work on similar auto-immune disorders effecting or destroying the myelin sheath like Transverse Myelitis I hope.
11 posted on 04/24/2009 9:15:48 PM PDT by cva66snipe (Two Choices left for U.S. One Nation Under GOD or One Nation Under Judgement? Which one say ye?)
[ Post Reply | Private Reply | To 9 | View Replies]

To: wagglebee; Coleus; Peach; airborne; Asphalt; Dr. Scarpetta; I'm ALL Right!; StAnDeliver; ovrtaxt; ..
Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis

The stromal vascular fraction (SVF) of adipose tissue is known to contain mesenchymal stem cells (MSC), T regulatory cells, endothelial precursor cells, preadipocytes, as well as anti-inflammatory M2 macrophages. Safety of autologous adipose tissue implantation is supported by extensive use of this procedure in cosmetic surgery, as well as by ongoing studies using in vitro expanded adipose derived MSC. Equine and canine studies demonstrating anti-inflammatory and regenerative effects of non-expanded SVF cells have yielded promising results. Although non-expanded SVF cells have been used successfully in accelerating healing of Crohn's fistulas, to our knowledge clinical use of these cells for systemic immune modulation has not been reported. In this communication we discuss the rationale for use of autologous SVF in treatment of multiple sclerosis and describe our experiences with three patients. Based on this rationale and initial experiences, we propose controlled trials of autologous SVF in various inflammatory conditions.

You can access a pdf link at the source, apparently.

12 posted on 04/24/2009 9:19:55 PM PDT by neverdem (Xin loi minh oi)
[ Post Reply | Private Reply | To 2 | View Replies]

To: Ellendra

http://clinicaltrials.gov/


13 posted on 04/24/2009 9:22:31 PM PDT by neverdem (Xin loi minh oi)
[ Post Reply | Private Reply | To 6 | View Replies]

To: cgk

Thanks for the ping.

Lord knows, I have plenty of adipose tissue...in fact I have more than enough for myself...I could be a donor! :)


14 posted on 04/25/2009 3:52:47 AM PDT by dawn53
[ Post Reply | Private Reply | To 9 | View Replies]

To: wagglebee

funny that the disease predominantly effects women yet they say the three test subjects were men.


15 posted on 04/25/2009 3:57:16 AM PDT by Puddleglum (Obama's just another word for nothin' left to lose)
[ Post Reply | Private Reply | To 1 | View Replies]

To: neverdem

BTTT


16 posted on 04/26/2009 6:02:42 PM PDT by Dr. Scarpetta
[ Post Reply | Private Reply | To 12 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
News/Activism
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson