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Stem Cells May Offer New Way to Treat Blocked Arteries (Adult Stem Cells)
HealthDay via Yahoo ^ | May 19, 2009 | Ed Edelson

Posted on 05/19/2009 4:14:38 PM PDT by neverdem

TUESDAY, (HealthDay News) -- Injecting bone marrow cells into the heart's muscular wall restored blood flow to hearts with blocked arteries for which conventional treatments had proven ineffective, Dutch physicians have reported.

"I think this is very good news for patients who are at the end of the line and have no options left," said Dr. Douwe E. Atsma, an interventional cardiologist at Leiden University Medical Center and an author of the study, which appears in the May 20 issue of the Journal of the American Medical Association.

The 50 people in the study, 43 of them men, were experiencing angina, or severe chest pain, because of blockages in their heart arteries. All had undergone several artery-opening procedures, such as angioplasty or bypass surgery, to restore blood flow, but such measures would no longer help them, Atsma said.

Half of the participants received injections of cells taken from their own bone marrow, and the others received inactive cell injections. After three months, the responses were varied, with some participants reporting complete relief and others with partial benefits.

"The most important thing is that the amount of ischemia [artery blockage] was halved" in those given the marrow cells, Atsma said. "The amount of tissue with ischemia was reduced, heart function improved significantly in a small way and their grades of quality of life were higher."

Two earlier and smaller trials of bone marrow cell therapy for heart disease had produced conflicting results, Atsma said. "We are the largest trial to date and the first to demonstrate a decrease in ischemia," he said.

The results were so good, Atsma said, that the participants who had gotten the dummy injections have since been given bone marrow cell therapy, and "we now consider it an option for patients in the same condition," he said...

(Excerpt) Read more at news.yahoo.com ...


TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: adultstemcells; cad; chd; stemcells
Intramyocardial Bone Marrow Cell Injection for Chronic Myocardial Ischemia
1 posted on 05/19/2009 4:14:38 PM PDT by neverdem
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To: Coleus; Peach; airborne; Asphalt; Dr. Scarpetta; I'm ALL Right!; StAnDeliver; ovrtaxt; ...

Stem Cell/Regenerative Medicine Ping


2 posted on 05/19/2009 4:18:46 PM PDT by neverdem (Xin loi minh oi)
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To: neverdem

I thought if your bone marrow got into your bloodstream, you died. Where’d I get that idea?


3 posted on 05/19/2009 4:22:53 PM PDT by mamelukesabre (Si Vis Pacem Para Bellum (If you want peace prepare for war))
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Bone marrow = stem cells


4 posted on 05/19/2009 4:26:37 PM PDT by ak267
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To: mamelukesabre
The cells are injected into the muscle tissue, not directly into blood vessels. In young heart injury patients, it is not uncommon to see the body make new blood vessels to bring blood to o2 starved muscle tissue.
5 posted on 05/19/2009 4:33:07 PM PDT by MHGinTN (Believing they cannot be deceived, they cannot be convinced when they are deceived.)
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To: ak267

Its my understanding that research with adult stem cells have been much more successful than embryonic in many instances. For example the Brazilian adult stem cell study that “cured” patients of diabetes.


6 posted on 05/19/2009 4:47:53 PM PDT by brwnsuga (Proud, BLACK, Beautiful, Conservative!!!)
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To: mamelukesabre
Maybe you were thinking of a fat embolism?When a major bone is fractured,it can release a fat particle that can cause an embolism.
7 posted on 05/19/2009 5:01:37 PM PDT by nomad
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To: neverdem
Didn`t Barky cut off federal funding for IPS cell research?
8 posted on 05/19/2009 5:04:25 PM PDT by nomad
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To: neverdem

They always put this stuff out here; and then we never hear about it again.


9 posted on 05/19/2009 5:10:02 PM PDT by freekitty (Give me back my conservative vote.)
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To: nomad

Maybe. Does that cause a fever?


10 posted on 05/19/2009 5:18:43 PM PDT by mamelukesabre (Si Vis Pacem Para Bellum (If you want peace prepare for war))
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To: brwnsuga

That’s why they need so many embryonic stem cells - they haven’t been successful yet. Maybe God doesn’t WANT them to be successful with something that kills babies.


11 posted on 05/19/2009 5:39:48 PM PDT by RebelTXRose
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To: brwnsuga
Its my understanding that research with adult stem cells have been much more successful than embryonic in many instances.

...so far, in ALL instances. That is why it is so important that the left keeps people ignorant of the difference between embryonic stem cells and all other stem cells, usually called adult, which is also misleading. Many people think that those of us who are opposed to embryonic stem cell research are opposed to all stem cell research. The left, dems and DBM, have a vested interest in keeping this misinformation going.

12 posted on 05/19/2009 5:46:53 PM PDT by Freee-dame
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To: nomad
Didn`t Barky cut off federal funding for IPS cell research?

NIH policy loosening stem cell research restrictions disappoints both sides in debate

I didn't see any thing about adult stem cell research or induced pluripotent stem cells besides banning their use in human/animal hybrids, aka chimeras.

13 posted on 05/19/2009 5:49:33 PM PDT by neverdem (Xin loi minh oi)
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To: mamelukesabre
That I don`t know.An embolism is a free moving particle in the circulatory system,when it`s stationary or gets stuck,its a thrombus.Thats usually the cause of a blockage or ischemia,like in a heart attack.
14 posted on 05/19/2009 6:14:54 PM PDT by nomad
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To: neverdem
I could swear I read an article posted hear, back when he reinstated the federal funds for embryonic research, that said he also cut funding for adult or IPS research.
15 posted on 05/19/2009 6:19:46 PM PDT by nomad
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To: nomad

Meant to say “here”,my bad.


16 posted on 05/19/2009 6:22:54 PM PDT by nomad
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To: neverdem

Very interesting...


17 posted on 05/19/2009 7:20:57 PM PDT by Dr. Scarpetta
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To: brwnsuga

You can also add at least two eye diseases, MS and a few others. Embyonic has been one, big zero so far.


18 posted on 05/19/2009 8:26:56 PM PDT by ak267
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You can also add type 1 and type 2 diabetes (promising results!!!!)


19 posted on 05/19/2009 8:32:10 PM PDT by ak267
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To: ak267

emryonic stem cell research is big business for Planned Parenthood and their ilk. This is why people don’t know the real data.


20 posted on 05/20/2009 4:58:30 AM PDT by brwnsuga (Proud, BLACK, Beautiful, Conservative!!!)
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To: neverdem
As the Scriptures say, we are fearfully, wonderfully made.

God gave us the means by which we can treat diseases, by using the very cells which make up our own bodies.

21 posted on 05/20/2009 8:45:57 AM PDT by SuziQ
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To: nomad
I could swear I read an article posted hear, back when he reinstated the federal funds for embryonic research, that said he also cut funding for adult or IPS research.

He may have cut off FEDERAL funding, but I believe that companies can still do the research on their own dimes. The biggest difference here is that research using embryonic stem cells has not shown any promise, therefore companies didn't want to take the financial risk. Adult stem cells, on the other hand, HAVE shown great promise, and I'm thinking that companies, looking to score big in patents, etc, would be willing to use their own money to fund this research.

22 posted on 05/20/2009 8:57:14 AM PDT by SuziQ
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