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Vital drug for people with lupus running out after unproven Covid-19 link: Italy and France now prescribing hydroxychloroquine for coronavirus
The Guardian ^ | 03/28/2020 | Sarah Boseley

Posted on 03/28/2020 8:04:47 AM PDT by SeekAndFind

A stampede for an unproven “cure” for Covid-19 is clearing the pharmacy shelves of a medicine that is vital for up to 5 million people around the world suffering from lupus, as countries bow to populist pressure and abandon the trials that would show whether hydroxychloroquine works against coronavirus infection.

Both Italy and France have said doctors can now prescribe hydroxychloroquine – a less toxic version of the malaria drug chloroquine – even though there is no robust evidence to prove that it is effective against Covid-19.

Popular pressure for access to the drug has been ramped up by pronouncements from presidents Donald Trump in the US and Jair Bolsonaro in Brazil, both of whom have claimed it is a cure. An Australian businessman, the former politician Clive Palmer, has pledged to fund 1m doses “to ensure all Australians would have access to the drug as soon as possible”.

But the drug is already running out for people with lupus, a disorder of the immune system, who rely on it to stay well. Shortages are being reported from the UK to Thailand to France. India, which manufactures the raw ingredient, has banned all exports of the chemical to safeguard its own supplies and recommended all health workers to take the drug to protect themselves from the virus.

“We are incredibly concerned at the moment,” said Paul Howard of Lupus UK. “We started receiving inquiries from patients across the UK about a week ago. That’s been rapidly increasing – more and more people each day.”

For 90% of the more than 60,000 people in the UK with lupus, hydroxychloroquine is the mainstay of their treatment, preventing their immune system making too many antibodies, which can otherwise attack the body’s organs – mainly the kidneys and the skin,

(Excerpt) Read more at theguardian.com ...


TOPICS: Culture/Society; Foreign Affairs; News/Current Events
KEYWORDS: businessopportunity; coronavirus; hydroxychloroquine; lupus; sarahboseley; unfilledmarket; unitedkingdom
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To: the OlLine Rebel

Fortunately, this drug hasn’t been used for malaria in many years. Malaria became resistant to it years ago. Its use is deprecated for Malaria.

I took this drug or its cousins for Malaria prophylaxis a long time ago.

Still got Malaria.


41 posted on 03/28/2020 8:36:49 AM PDT by Black Agnes
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To: joe fonebone

I read an Israel company is sending us 6 million pills.


42 posted on 03/28/2020 8:37:33 AM PDT by proust (Justice delayed is injustice.)
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To: SeekAndFind; All

new yorker on hcq march 27

https://www.newyorker.com/news/news-desk/donald-trumps-dangerous-messaging-about-a-possible-coronavirus-treatment


43 posted on 03/28/2020 8:38:03 AM PDT by SteveH (intentionally blank)
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To: proust

https://www.thestreet.com/investing/teva-donates-malaria-pills-to-fight-coronavirus-in-us


44 posted on 03/28/2020 8:38:41 AM PDT by proust (Justice delayed is injustice.)
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To: the OlLine Rebel

That can only happen if nobody makes more.

I have noticed that the sheep who bleat the loudest about the short supply never want to get involved in expanding the supply.


45 posted on 03/28/2020 8:39:16 AM PDT by MrEdd (Caveat Emptor)
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To: chiller

Exactly, the pushback has been over the top.

As Trump says, a lot of people out there (about 48% of the US) want him to fail, which means this drug can’t be the cure.

We all know it works. The NY drug trial started last Wednesday, and by early this week, they won’t be able to stifle the stories of its success. They will try.”We need a controlled Phase 1, Phase 2, Phase 3 process.” BS - people are dying. Roll it out!

There are several manufacturers, hopefully they are in full production.

Trump gets this and will force their hands (and for God’s sake, get rid of Fauci. What a mush.)


46 posted on 03/28/2020 8:39:46 AM PDT by dan on the right
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To: SeekAndFind

It is not ‘helpful’ to progressives for hydroxychloroquine to work.
Seems they want/need piles of dead.
Almost ghoulish.


47 posted on 03/28/2020 8:39:57 AM PDT by glasseye ( If 50,000 people say a foolish thing, it is still a foolish thing. H. L. Mencken)
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To: SeekAndFind

“Both Italy and France have said doctors can now prescribe hydroxychloroquine – a less toxic version of the malaria drug chloroquine – even though there is no robust evidence to prove that it is effective against Covid-19.”

Media likes to say things like this about it because Trump.

Note how now they’re saying “no _robust_ evidence”. Now, not no evidence.

And what do they think? Brand new virus, there are zero clinical trials on any drug to treat this, or SARS or MERS.

This headline or argument about “no evidence” in clinical would be true for anything anyone tries to use.

But they only harp on chloroquine.

They don’t harp on azithromycin. Only chloroquine.


48 posted on 03/28/2020 8:41:11 AM PDT by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: Hugh the Scot

I do not know it all, and i am not in a panic... i do know about manufacturing processes and the time involved. I know this because i fed my family with this knowledge.

It is painfully obvious that you, sir, cannot present a knowledgeable argument for or against what I have stated.

I will not piss off...
You, however, are free to do so


49 posted on 03/28/2020 8:42:02 AM PDT by joe fonebone (Communists Need To Be Eliminated)
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To: MrEdd

We no longer even make the equipment to make the equipment to do so.

Hopefully someone is beginning to do so in a hurry. We can’t afford to let this kind of stuff be outsourced outside our borders.


50 posted on 03/28/2020 8:42:14 AM PDT by Black Agnes
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To: redgolum

It’s already happening.

https://www.pharmtech.com/suppliers-plan-chloroquine-capacity


51 posted on 03/28/2020 8:42:19 AM PDT by Hugh the Scot ("Jesus was a fundamentalist".- BipolarBob)
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To: pelican001

RE:They a massively ramping up production of ventilators, but why not chloroquine?

But they are ramping up production of chloroquine

See here:

https://www.fiercepharma.com/pharma/bayer-preps-u-s-donation-malaria-med-chloroquine-to-help-covid-19-fight-report

Bayer donates millions of tablets of chloroquine to help in COVID-19 fight

https://www.fiercepharma.com/pharma/new-commitments-mylan-and-teva-move-to-supply-tens-millions-hydroxychloroquine-tablets-to

Novartis, Mylan and Teva to supply tens of millions of chloroquine tablets to fight COVID-19


52 posted on 03/28/2020 8:43:21 AM PDT by SeekAndFind (look at Michigan, it will)
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To: SeekAndFind

It’s not “unproven.”


53 posted on 03/28/2020 8:44:03 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: dmet
"Most times a Rx will only provide you with a 30 day or 60 day supply for a patient that will have to take it everyday of their life. "

And for this used as a curative you only need a two-week dose time. You might need a longer use time if used as prophylaxis, but that use really "is" unproven.

54 posted on 03/28/2020 8:44:14 AM PDT by Wonder Warthog (The Hog of Steel and NRA Life Member)
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To: pelican001

MORE here:

https://www.pharmtech.com/suppliers-plan-chloroquine-capacity

Following reports that hydroxychloroquine and chloroquine are under evaluation in clinical trials as a potential treatment of COVID-19, drug companies are donating doses and planning for ramping up supply.


55 posted on 03/28/2020 8:44:55 AM PDT by SeekAndFind (look at Michigan, it will)
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To: SeekAndFind

Where are those donated tablets produced?


56 posted on 03/28/2020 8:46:50 AM PDT by Black Agnes
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To: joe fonebone
"Do we take the drug away from the people who have used and needed it for years?

For Lupus and RA users, doing without a couple of weeks dose isn't likely to be terminal....for someone in a hospital with COV it quite likely is....the answer, IMO, is YES.

"The supply is very limited. What is the solution?"

We have no idea what the total supply in the US is, as we don't know how much the DOD has in stock...which now, thanks to Trump, can be released for civilian use due to his activation of emergency powers.

57 posted on 03/28/2020 8:48:57 AM PDT by Wonder Warthog (The Hog of Steel and NRA Life Member)
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To: stinkerpot65

I am hopeful about this drug, so why aren’t any Red state governors making it available? I keep reading about Blue state governors banning it, like it’s some kind of plot to kill people to hurt Trump..... That would make sense of every governor was a Democrat, but that’s not the case.... This whole thing is very strange


58 posted on 03/28/2020 8:50:36 AM PDT by The Fop (God Bless Donald Trump, Frank Sinatra, Joan Rivers, and the Fightin' Rat Pack Wing of the GOP)
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To: FreedomPoster

If the real objective was to make sure that lupus and arthritis patients continue to get theirs, then a simple directive to pharmacies, saying to fill long term users before flu patients, would accomplish that.

But that’s not their real objective. A cheap and effective treatment would undermine Big Pharma.


59 posted on 03/28/2020 8:51:03 AM PDT by SauronOfMordor (A Leftist can't enjoy life unless they are controlling, hurting, or destroying others)
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To: joe fonebone
"A drug that is not widely used is not widely produced."

Except that hydroxychloroquine IS both widely used and widely produced, plus being stockpiled by the military.

60 posted on 03/28/2020 8:51:16 AM PDT by Wonder Warthog (The Hog of Steel and NRA Life Member)
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