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The Great DNA Hunt (Genetic archaeology)
Archaeological Institute of America ^ | Volume 49 Number 5, September/October 1996 | by Tabitha M. Powledge and Mark Rose

Posted on 02/25/2006 9:58:16 PM PST by restornu

DNA can be used to understand the evolution of modern humans, trace migrations of people, identify individuals, and determine the origins of domestic plants and animals. DNA analysis, as one scholar put it, is "the greatest archaeological excavation of all time." Because ancient DNA molecules are normally so few and fragmented, and preserved soft tissues so rare, scientists had little hope of finding and analyzing it. But two breakthroughs have made this possible: the polymerase chain reaction (PCR), a method for copying any fragment of DNA, and the successful recovery of DNA from preserved hard tissues, bones and teeth, that are durable and relatively abundant.

DNA analysis traced human ancestry back to an African "Eve," setting off debate about how modern humans evolved. While there was general agreement that Homo erectus dispersed from Africa across Asia between 1 and 2 million years ago, what happened next remained a question. The "out-of-Africa" hypothesis contended that modern humans developed in Africa and migrated from there recently, driving H. erectus into extinction. Proponents of a "multiregional" hypothesis held that H. erectus populations evolved into modern humans in many regions, and that these groups later bred with each other and with groups that emigrated from Africa. The Eve study examined mitochondrial DNA (mtDNA), which is passed only by mothers to their offspring. The researchers, Rebecca Cann, Mark Stoneking, and the late Allan Wilson, estimated that the ancestor of all surviving mt DNA types lived between 140,000 and 290,000 years ago. When did the migrations from Africa take place? They dated the oldest cluster of mtDNA types with no modern African representation to between 90,000 and 180,000 years ago. These populations might have left Africa at about that time, but the mtDNA data could not determine exactly when.

Geneticist Alan Templeton pointed out statistical and sampling flaws in the study. Its results, he argued, were in part dictated by the order in which the data were fed into the computer. Others questioned the reliability of "molecular clocks" and the rate of mutation in the human mtDNA used in calculating Eve's date. The genetic diversity of African populations was confirmed by later studies and is now generally accepted, but, according to Templeton, proponents of the out-of-Africa hypothesis assumed that genetic diversity reflected only the age of a population rather than population size. He contends that Africa has greater genetic diversity because its prehistoric population was probably larger than elsewhere. Recently John Relethford and Henry Harpending have argued that differences in ancient population size could mimic a recent African origin of modern humans. The data reflect population dynamics, they say, and do not support one model of modern human origins over another.

Scientists are also studying DNA from the Y chromosome, which is passed only from father to son and is not recombined with the mother's genes. Because changes in the Y chromosome are caused only by mutations, as in mtDNA, it may be used as a clock. Assuming that all living humans share a common male ancestor, it should be possible to estimate when he lived. According to geneticist Robert Dorit, the first modern human male lived some 270,000 years ago. The most recent research on modern human origins, by John Armour, examined nuclear DNA of populations from around the world. Armour and his colleagues conclude that the evidence fits with the development of modern humans in Africa and an emigration by a small number of them that became the basis for non-African populations. These observations, they say, are more difficult to reconcile with a multiregional model for the origin of modern humans.

New DNA studies by Bryan Sykes have challeneged the leading theory about the spread of agriculture into Europe. In 1984 Albert Ammerman and geneticist Luigi Luca Cavalli-Sforza of Stanford University proposed that it was people practicing agriculture who spread into Europe, rather than the idea of agriculture. They argued that agricultural productivity led to population growth, and that, as the population grew, early farmers gradually moved into new land inhabited by fewer hunter-gatherers. Thus the practitioners of agriculture spread from Anatolia, beginning about 7000 B.C., to Greece and across all of Europe, ending in Britain and Scandinavia about 4000 B.C. Using mtDNA analysis, Sykes claims that the ancestors of most modern Europeans arrived at least 20,000 years ago, long before the supposed arrival of Neolithic farmers. In analyzing mtDNA from more than 800 modern Europeans, Sykes and his colleagues identified at least five main groups. Four of the five groups date to well before the last glacial peak, with ages ranging from 35,000 to 25,000 years ago. The fifth group is much younger in Europe (6,000 to 10,000 years ago) and has clear affinities to Near Eastern mtDNA. Sykes and his colleagues accept this as the genetic echo of the spread of agriculture, but note that it is fairly weak. They conclude that, far from being overwhelmed by incoming farmers, the indigenous hunter-gatherer population remained intact and learned how to farm.

Documentation of the early presence of Caucasian people in northwestern China, and information about their affinities with either modern European or Indo-Iranian populations, could contribute to the debate about the spread of Indo-European languages. Chinese and Uyghur archaeologists have been excavating naturally mummified bodies there since the 1970s. Paolo Francalacci of the University of Sássari, Sardinia, took samples from several of the bodies, dated to 3,200 years ago DNA analysis for these mummies suggest a possible European origin, although further research is needed to identify them more precisely. As part of a larger project, Chinese geneticist Du Ruofu has been collected samples of mtDNA from modern Tarim Basin populations. Comparison will determine how much of the ancient genetic composition survives.

Most scholars believe that people from the Asian continent came to the Japanese archipelago in two migrations. An early wave brought the Jomon culture--hunter-gatherers who made pottery--to Japan more than 10,000 years ago. A second migration began about 2,300 years ago, when the Yayoi people, entering from the Korean Peninsula, brought weaving, metalworking, and rice culture to Japan. First appearing on the southwestern island of Kyushu, by ca. A.D. 300 Yayoi culture had spread throughout most of Japan, altering all local cultures south of Hokkaido, the northernmost island. Michael F. Hammer and Satoshi Horai are examining the extent to which the Jomon did or did not contribute genetically to the modern Japanese. Current hypotheses can be classified as replacement, hybridization, or transformation. In the first, Yayoi immigrants replaced the Jomon people. Hybridization theories claim that modern Japanese are descended from both groups, in which case they should have genes deriving from both the Jomon and Yayoi people. Transformation theories posit that modern Japanese people gradually evolved from the Jomon. Hammer and Horai, based on their study of the Y chromosome, conclude that hybridization, a mixing of Jomon and Yayoi stocks, is the most likely explanation for the origin of modern Japanese.

Nonhuman DNA has great potential for shedding light on cultural practices. Recent work by Daniel Bradley is a case in point. Before now it was assumed that cattle were first domesticated in the Near East. African, European, and Indian cattle were all thought to be descended from a domesticated Near Eastern progenitor, and to have developed into characteristic breeds afterward. Bradley and his colleagues have determined that Indian cattle broke off from an ancestral lineage between 117,000 and 275,000 years ago. The lineage split again about 22,000 to 26,000 years ago into groups that gave rise to modern African and European cattle. These are startling results because cattle in the Near East were not domesticated until about 9,000 years ago, and cattle in India and Africa were genetically distinct before then. The latter two could not possibly be descended from domesticated Near Eastern cattle, as was thought, but must have been domesticated independently.

Geneticist Terence A. Brown and his colleagues have devised a way to identify types of wheat using DNA analysis. This will make it possible to determine whether primitive wheats or modern varieties were grown at a site. The higher productivity of modern varieties means that a larger population could be supported, and fewer people had to be involved in farming. This may have been a factor that sustained the rise of classical civilizations. Brown also hopes to use similarities and differences in wheat DNA to investigate the relationships between Celts and Romans in Britain. Did the Romans bring their own wheat, or did they rely on indigenous agriculture to support the Roman community?

This is the first in a two-part series on genetic archaeology. Our second installment, in the November/December issue, focuses on DNA investigations that challenge the most widely accepted model of how the New World was colonized.

Genealogy of New Kingdom Pharaohs and Queens by Scott Woodward

Egyptologists have struggled with the genealogy of New Kingdom (1570-1070 B.C.) pharaohs for more than a century. Many royal mummies from this period have been identified, either by modern scholars or 20th Dynasty priests who rescued some of them from the depredations of tomb robbers. But we cannot always trust these identifications. The incomplete historical record is exacerbated by the fact that royal brothers and sisters, and even fathers and daughters, intermarried. Uncertainty abounds: How was a particular pharaoh related to his successor? Which of a pharaoh's wives was the mother of his heir? There are also many unidentified mummies. Could one of them be Hatshepsut or Akhenaten? Were the two fetuses found in Tutankhamun's tomb carried by his wife Ankhensenpaaten? Since 1993 microbiologist Scott Woodward has been analyzing DNA from the mummified remains of these pharaohs and queens, in cooperation with Nasry Iskander, chief curator of the royal mummies at the Egyptian Museum in Cairo.


TOPICS: Culture/Society
KEYWORDS: africanhistory; ancestry; crevolist; dna; godsgravesglyphs; hatshepsut; helixmakemineadouble
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1 posted on 02/25/2006 9:58:20 PM PST by restornu
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To: SunkenCiv; blam; RadioAstronomer

Genetic archaeology zooms in on the origins of modern humans.


2 posted on 02/25/2006 9:59:45 PM PST by restornu (words of Zenock to be crucified, of Neum to be buried in a sepulcher,of Zenos three days of darknes)
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To: restornu

bookmark


3 posted on 02/25/2006 10:03:46 PM PST by sageb1 (This is the Final Crusade. There are only 2 sides. Pick one.)
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To: restornu

ping


4 posted on 02/25/2006 10:04:52 PM PST by kinsman redeemer (The real enemy seeks to devour what is good.)
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To: restornu
Egyptologists have struggled with the genealogy of New Kingdom (1570-1070 B.C.) pharaohs for more than a century.

Many royal mummies from this period have been identified, either by modern scholars or 20th Dynasty priests who rescued some of them from the depredations of tomb robbers.

But we cannot always trust these identifications. The incomplete historical record is exacerbated by the fact that royal brothers and sisters, and even fathers and daughters, intermarried. Uncertainty abounds:

How was a particular pharaoh related to his successor?

Which of a pharaoh's wives was the mother of his heir?

There are also many unidentified mummies.

Could one of them be Hatshepsut or Akhenaten?

Were the two fetuses found in Tutankhamun's tomb carried by his wife Ankhensenpaaten?

Since 1993 microbiologist Scott Woodward has been analyzing DNA from the mummified remains of these pharaohs and queens, in cooperation with Nasry Iskander, chief curator of the royal mummies at the Egyptian Museum in Cairo.

5 posted on 02/25/2006 10:05:10 PM PST by restornu (words of Zenock to be crucified, of Neum to be buried in a sepulcher,of Zenos three days of darknes)
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For later ===> Placemarker <===
6 posted on 02/25/2006 10:06:54 PM PST by Coyoteman (I love the sound of beta decay in the morning!)
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To: restornu

YEC INTREP


7 posted on 02/25/2006 10:22:01 PM PST by LiteKeeper (Beware the secularization of America; the Islamization of Eurabia)
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To: restornu

ping


8 posted on 02/25/2006 10:29:47 PM PST by RedCell
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To: restornu

You mean it thinks its zooming in on the origins of modern humans? So far, alot of the more controversial pronouncements are being proven wrong just a few years later. Reminds me of peking man and alot of other so called early humanoids, which have been proven fake at a later date.


9 posted on 02/26/2006 2:33:41 AM PST by son of caesar
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To: Junior

Archive?


10 posted on 02/26/2006 4:16:26 AM PST by PatrickHenry (Virtual Ignore for trolls, lunatics, dotards, scolds, & incurable ignoramuses.)
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To: son of caesar
Reminds me of peking man and alot of other so called early humanoids, which have been proven fake at a later date.

You need to do some research. Peking Man was not a fake.

Near as I can remember, the closest to a fake was the Piltdown Man hoax.

Can you support your contention?

(Hint: Don't rely on the creationist websites, as they are full of mis-information on this topic.)

11 posted on 02/26/2006 7:17:44 AM PST by Coyoteman (I love the sound of beta decay in the morning!)
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To: son of caesar
So far, alot of the more controversial pronouncements are being proven wrong just a few years later.

That's how science advances.

In fact, that how everything advances,

two steps forward, one step back

two steps forward, two steps back,

three step forward, and so on.

The kind of advance in knowledge you are looking for will not occur in this life.

12 posted on 02/26/2006 7:51:02 AM PST by Balding_Eagle (REAL men vote Republican)
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To: restornu

I thought the creationists had established the last common male ancestor as Noah. That's a bit shy of 270,000 years.


13 posted on 02/26/2006 7:56:00 AM PST by js1138
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To: PatrickHenry

Mais oui.


14 posted on 02/26/2006 10:48:53 AM PST by Junior (Identical fecal matter, alternate diurnal period)
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To: restornu

Molecular Clockwork And Related Theories
Athena Review
Posted on 02/25/2006 5:40:40 PM EST by blam
http://www.freerepublic.com/focus/f-news/1585561/posts


15 posted on 02/26/2006 6:46:54 PM PST by SunkenCiv (My Sunday Feeling is that Nothing is easy. Goes for the rest of the week too.)
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To: restornu
Thanks restornu.

Just adding this to the GGG catalog, not sending a general distribution.

To all -- please ping me to other topics which are appropriate for the GGG list. Thanks.
Please FREEPMAIL me if you want on or off the
"Gods, Graves, Glyphs" PING list or GGG weekly digest
-- Archaeology/Anthropology/Ancient Cultures/Artifacts/Antiquities, etc.
Gods, Graves, Glyphs (alpha order)

16 posted on 02/26/2006 6:47:34 PM PST by SunkenCiv (My Sunday Feeling is that Nothing is easy. Goes for the rest of the week too.)
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To: Balding_Eagle

Perhaps I was not clear on my post vis a vis the other posts I was responding too. When I said that great scientific pronouncements regarding DNA in the particular arena of the evolutionists are generally proven wrong just a few years later, that is precisely what I mean. Of course, science has starts and stops, but in no other area of science is it so polluted with a particular relgion. That relgion would be the anti God relgion.


17 posted on 02/27/2006 1:08:23 AM PST by son of caesar
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To: son of caesar
So far, alot of the more controversial pronouncements are being proven wrong just a few years later.

That's rather an overstatement. It's more accurate to say that it has been shown that the full picture is more complicated than the one narrow "slice" of the picture that various prior studies have produced.

18 posted on 02/27/2006 1:13:09 AM PST by Ichneumon
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To: Ichneumon

You know what? The anti God folks abound with uber overstatements, so I choose to use some of their own ammo right back at em. Now tell me about the Peking man thing and the overstatements used by that crowd.


19 posted on 02/27/2006 1:22:18 AM PST by son of caesar
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To: Balding_Eagle

...two steps back, one step forward.


20 posted on 02/28/2006 5:51:37 AM PST by kinsman redeemer (The real enemy seeks to devour what is good.)
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