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Discovery in Neuroscience Could Help Re-Wire Appetite Control
ScienceDaily ^ | Apr. 5, 2013 | NA

Posted on 04/06/2013 9:05:01 PM PDT by neverdem

Researchers at the University of East Anglia (UEA) have made a discovery in neuroscience that could offer a long-lasting solution to eating disorders such as obesity.

It was previously thought that the nerve cells in the brain associated with appetite regulation were generated entirely during an embryo's development in the womb and therefore their numbers were fixed for life.

But research published today in the Journal of Neuroscience has identified a population of stem cells capable of generating new appetite-regulating neurons in the brains of young and adult rodents.

Obesity has reached epidemic proportions globally. More than 1.4 billion adults worldwide are overweight and more than half a billion are obese. Associated health problems include type 2 diabetes, heart disease, arthritis and cancer. And at least 2.8 million people die each year as a result of being overweight or obese.

The economic burden on the NHS in the UK is estimated to be more than £5 billion annually. In the US, the healthcare cost tops $60 billion.

Scientists at UEA investigated the hypothalamus section of the brain -- which regulates sleep and wake cycles, energy expenditure, appetite, thirst, hormone release and many other critical biological functions. The study looked specifically at the nerve cells that regulate appetite.

The researchers used 'genetic fate mapping' techniques to make their discovery -- a method that tracks the development of stem cells and cells derived from them, at desired time points during the life of an animal.

They established that a population of brain cells called 'tanycytes' behave like stem cells and add new neurons to the appetite-regulating circuitry of the mouse brain after birth and into adulthood.

Lead researcher Dr Mohammad K. Hajihosseini, from UEA's school of Biological Sciences, said: "Unlike dieting, translation of this discovery could eventually offer a permanent solution for...

(Excerpt) Read more at sciencedaily.com ...


TOPICS: Culture/Society; News/Current Events; Testing
KEYWORDS: adultstemcells; appetite; leptin; neuropeptidey; obesity; stemcells; tanycytes; type2diabetes

1 posted on 04/06/2013 9:05:01 PM PDT by neverdem
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To: neverdem
Researchers at the University of East Anglia

I see East Anglia and I think FRAUD. I stop reading.

2 posted on 04/06/2013 9:13:32 PM PDT by FatherofFive (Islam is evil and must be eradicated)
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To: neverdem
Lead researcher Dr Mohammad K. Hajihosseini, from UEA's school of Biological Sciences, said: "Unlike dieting, translation of this discovery could eventually offer a permanent solution for...

"Could eventually" usually means never when it comes to these PR releases.

3 posted on 04/06/2013 9:16:56 PM PDT by Moonman62 (The US has become a government with a country, rather than a country with a government.)
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To: Moonman62; FatherofFive
"Could eventually" usually means never when it comes to these press releases

Did you read the abstract? It's linked at the end of the press release. It mentions leptin and Neuropeptide-Y. The former is involved with satiety, and the latter is involved with food and sleep deprivation.

A few clowns at the University of East Anglia shouldn't tarnish all scientists.

4 posted on 04/06/2013 9:41:47 PM PDT by neverdem ( Xin loi min oi)
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To: neverdem

It would have been better if neuroscience had found a lasting cure for neuropathy.


5 posted on 04/06/2013 9:43:07 PM PDT by 353FMG ( I do not indicate whether I am serious or sarcastic -- I respect FReepers too much.)
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To: Coleus; Peach; airborne; Asphalt; Dr. Scarpetta; I'm ALL Right!; StAnDeliver; ovrtaxt; ...
Droplet printing assembles soft networks Think of biological scaffolds.

FReepmail me if you want on or off my stem cell/regenerative medicine ping list.

6 posted on 04/06/2013 10:00:31 PM PDT by neverdem ( Xin loi min oi)
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To: 353FMG
It would have been better if neuroscience had found a lasting cure for neuropathy.

You might have to regrow peripheral nerves that are damaged beyond repair. While this pertains to the central nervous system, they're are constant surprises in science. We don't know what we don't know.

7 posted on 04/06/2013 10:08:56 PM PDT by neverdem ( Xin loi min oi)
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To: neverdem
Still working on mind control--out in the daylight--for 'our own good', of course.

P$: $end grant$....

8 posted on 04/07/2013 12:45:07 AM PDT by Smokin' Joe (How often God must weep at humans' folly. Stand fast. God knows what He is doing)
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To: neverdem
Interesting, but I wonder how narrow this solution would be. Most obese people I know suffer from some form of depression. They eat comfort foods to excess and are sedentary in their pastimes. It's a neurological problem for certain.

OTOH, who in human history would have thought we'd ever have a problem with delivering too many calories. The entire history of humanity is one of near starvation and subsistence living. Thank capitalism, free markets and America's century of small government. Yet, you'll not hear a thing about it in any government school, documentary or MSM outlet. Go figure.

9 posted on 04/07/2013 5:11:04 AM PDT by 1010RD (First, Do No Harm)
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To: neverdem

appetite control


10 posted on 04/07/2013 5:11:31 AM PDT by quintr
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To: quintr

what could possibly go wrong??


11 posted on 04/07/2013 6:28:58 AM PDT by jonno (Having an opinion is not the same as having the answer...)
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