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Rabbits with brain injuries hop again after treatment with dendrimers. By tacking drugs onto molecules targeting rogue brain cells, researchers have alleviated symptoms in newborn rabbits that are similar to those of cerebral palsy in children. Cerebral palsy refers to a group of incurable disorders characterized by impairments in movement, posture and sensory abilities. In general, medicines tend to act broadly rather than influence certain sets of cells in the brain. “You don’t expect large molecules to enter the brain, and if they do, you don’t expect them to target specific cells, and immediately act therapeutically — but all of...

Enlarge Image Green light. Antibodies that bind to the transferrin receptor (green) can cross the blood-brain barrier and potentially help deliver therapies to neurons (red). Credit: Yu et al., Science Translational Medicine Any would-be cure for Alzheimer’s disease or other brain disorder faces a daunting obstacle: the blood-brain barrier. This nearly impenetrable lining in the capillaries of the brain keeps out viruses and other bad guys, but it also denies entry to many potential drugs and other treatments. Now researchers have devised a way to trick one of the gatekeepers in this cellular defense system into escorting a potentially...

New York Democratic Representative Anthony Weiner , a member of the House Subcommittee on Commerce, Trade and Consumer Protection, is using his public office to attack one of Glenn Beck’s key sponsors, Goldline, Inc. It seems that Goldline, Inc. has committed the heinous crime, according to Weiner, of exploiting Beck’s scaremongering about the collapsing economy to tout gold as a save haven and to overcharge for gold coins. Weiner is abusing the power of his office to intimidate Goldline into dropping its sponsorship of Beck, whom Weiner regards as a serious threat to his progressive agenda. Weiner wrote letters to...

http://www.youtube.com/watch?v=Vje2FtM_itw&feature=player_embedded

It was a mix of the old and the new Wednesday as the Denver/Boulder Better Business Bureau released its list of 2009’s Top 10 Scams and Ripoffs. The list includes both local and national activity. “While fraudulent checks, wire-transfer scams and vague free-trial offers continue to wreak havoc in the marketplace, other circumstances in 2009 made way for new schemes and unethical activity,” the BBB said in a news release. The bureau cited such events as Colorado’s storms, the H1N1 virus and the struggling economy as new areas for scammers. Dale Mingilton, president/CEO of the BBB, cautions consumers to: •...

For years, Better Business Bureau has educated consumers about not giving out personal information over the telephone or to anyone who shows up at their front door. With the U.S. Census process beginning, BBB advises people to be cooperative, but cautious, so as not to become a victim of fraud or identity theft. The first phase of the 2010 U.S. Census is under way as workers have begun verifying the addresses of households across the country. Eventually, more than 140,000 U.S. Census workers will count every person in the United States and will gather information about every person living at...

Fitch Cuts Russia's Sovereign Debt Rating 05 February 2009 By Nadia Popova / Staff Writer Fitch downgraded Russia's sovereign rating on Wednesday, prompting scorn from Russian investors over whether international agencies could offer credible ratings in view of their apparent miscalculations before the global crisis. Fitch lowered Russia's foreign and local currency ratings by a notch to BBB -- two rankings above junk -- over concerns about dwindling foreign exchange reserves, falling oil prices and corporate debt refinancing. It was the first time that Fitch has cut the country's rating since 1998, when Russia devalued the ruble and defaulted on...

Motorola Debt Downgraded to Junk Status ­Debt ratings agency, Standard and Poors (S&P) has dropped Motorola's long-term corporate credit rating to 'BB+' from 'BBB' - which is basically junk status - on the outlook for its mobile phone division. "The current rating action reflects continual operational challenges in the Mobile Devices unit, which are not likely to be reversed over the intermediate term, leading to depressed profitability and returns, adjusted debt leverage over 4x, and substantially diminished free cash flows." S&P also assigned a recovery rating of '3' to this debt, indicating the expectation for meaningful (50% to 70%) recovery...

'Billionaire Boys Club' member sought SAN FRANCISCO, April 21 (UPI) -- California authorities are looking for one of the "Billionaire Boys Club" members after the man failed to appear for a hearing on drug and other charges. Reza Eslaminia, 44, was to have reported to court regarding allegations of drug possession and driving with a suspended license.He also missed a March 29 court date. His attorney said he was unable to reach Eslaminia about the hearing but he expected him to surrender to authorities Friday, the San Francisco Chronicle reported. Superior Court of California Judge Stephen Hall issued a warrant...

Intro - " The Liberty League" www.libertyleague.com A friend called tonight and wanted an opinion regarding this new found company he is considering jumping into.I checked the site out, and could not discover what products were being sold, and when I clicked 'products' it asked for MY info. Out of curiosity, I then went to the BBB. The report was disturbing, so I posted it to my journal. Maybe this will save someone a little heartache." "The Better Business Bureau 4428 N. 12th Street Phoenix, AZ 85014-4585 602-264-1721 info@phoenix.bbb.org May Not Be Reproduced for Commercial or Sales Purposes LIBERTY LEAGUE...

WASHINGTON (Reuters) - Some Republican Party backers of abortion rights are upset with their party's new chairman, Ken Mehlman, for planning to host a salute next week to those who favor banning abortion. "This crosses the line," Ann Stone, national chair of Republicans for Choice, a political action group with about 100,000 members nationwide, said on Friday. Mehlman has scheduled an event on Monday to honor those who participate in the march that day against the 1973 U.S. Supreme Court decision that legalized abortion. our party's fight to protect the sanctity of life."

The Council of Better Business Bureaus has recommended that Apple Computer discontinue comparative performance claims regarding its Power Mac G5 desktop. Acting on a tip from Apple rival Dell, the council's National Advertising Division (NAD) "determined that the evidence provided by Apple did not provide a reasonable basis for its broad unqualified claims that its Power Mac G5 is 'the world's fastest, most powerful personal computer' and that it 'edged out the competition on integer.'"

[This is exactly as I received it by e-mail, seconds ago, from the Editor of the Redneck Republican Digest, sent to an affiliation of good folks (including some independents like me, and a few lapsed Democrats) that I have known for some six years now. The source URL is my own, because the form demands one and there is none for this message. But I can vouch for its accuracy.] I don't know if you guys are keeping up with O'Reilly. He complained about Ludicrous (a rap guy that gets pretty graphic I guess; let's just call him nasty to...

<p>WASHINGTON (AP) --  A national charity watchdog faulted the American Red Cross' Sept. 11 fund raising, saying solicitations it used to raise hundreds of million of dollars for victims of the terrorist attacks were misleading.</p> <p>In a report issued Thursday, the Better Business Bureau's Wise Giving Alliance said early Red Cross solicitations for the Sept. 11 Liberty Fund omitted the fact that the charity planned to use some of the donations for broad relief efforts. Later appeals that did disclose the Red Cross' plans for the money "did not do so in a clear and conspicuous manner that would be reasonably understood by potential donors given the circumstances of 9/11," the report found.</p>